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85,013 comparisons from ClinicalTrials.gov.

85,013 comparisons

Most participants first33,758 with no events in either group come last2,321 to 2,340 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
Right Ventricle Lead-Related Complications vs Summary of System and/or Procedure Related Complications Not Related to the RV Lead.: serious adverse events58 of 1,735

134 of 1,735

-4.4 points

-5.9 to -2.9

3,470NCT02235545

Optisure Lead Post Approval Study

Telmisartan (TRANSCEND) vs Placebo (TRANSCEND): TRANSCEND. Newly Diagnosed Diabetes124 of 1,710

165 of 1,751

-2.2 points

-4.0 to -0.3

3,461NCT00153101

Effectiveness and Safety of Ramipril Alone Compared With Telmisartan Alone and in Combination With Ramipril in Patients at High Risk for Cardiovascular Events. Patients Intolerant to Ramipril Were Entered in TRANSCEND, Telmisartan Compared to Placebo.

Group 1: Ad26.RSV.preF and RSV preF Protein vs Group 2: Placebo: Number of Participants With Solicited Systemic AEs up to 7 Days After Vaccination1,018 of 2,305

236 of 1,155

23.7 points

20.6 to 26.7

3,460NCT04908683

A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease in Adults Aged 60 Years and Older

Group 1: Ad26.RSV.preF and RSV preF Protein vs Group 2: Placebo: Number of Participants With Solicited Local Adverse Events (AEs) up to 7 Days After Vaccination1,076 of 2,305

169 of 1,155

32.0 points

29.1 to 34.9

3,460NCT04908683

A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease in Adults Aged 60 Years and Older

Spironolactone vs Placebo: serious adverse events835 of 1,722

855 of 1,723

-1.1 points

-4.5 to 2.2

3,445NCT00094302

Aldosterone Antagonist Therapy for Adults With Heart Failure and Preserved Systolic Function

IndIndacaterol vs Tiotropium: serious adverse events263 of 1,721

255 of 1,718

0.4 points

-2.0 to 2.8

3,439NCT00845728

Exacerbation Study

Rivaroxaban (Xarelto, BAY59-7939) vs Enoxaparin/VKA: serious adverse events222 of 1,718

252 of 1,711

-1.8 points

-4.1 to 0.5

3,429NCT00440193

Oral Direct Factor Xa Inhibitor Rivaroxaban in Patients With Acute Symptomatic Deep Vein Thrombosis - The EINSTEIN DVT Study

Empagliflozin-treated Patients vs Non-SGLT2i-treated Patients: Hospitalizations Due to Heart-failure in the Past 6 Months Before Baseline284 of 3,320

6 of 104

2.8 points

-3.5 to 6.0

3,424NCT05350202

Emp-Activity: Empagliflozin Functional Capacity

Staphylococcus Aureus 4-antigen (SA4Ag) vs Placebo: Number of Participants With Newly Diagnosed Chronic Medical Disorders From First Postoperative Evaluation on Day 42 Until Last Postoperative Evaluation on Day 18029 of 1,708

41 of 1,709

-0.7 points

-1.7 to 0.3

3,417NCT02388165

Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation

Staphylococcus Aureus 4-antigen (SA4Ag) vs Placebo: Number of Participants With Adverse Events (AEs) From The Day of Surgery (Day 1) Until First Postoperative Evaluation on Day 421,136 of 1,708

1,167 of 1,709

-1.8 points

-4.9 to 1.4

3,417NCT02388165

Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation

Staphylococcus Aureus 4-antigen (SA4Ag) vs Placebo: Number of Participants With Adverse Events (AEs) From Vaccination Until First Postoperative Evaluation on Day 421,198 of 1,708

1,213 of 1,709

-0.8 points

-3.9 to 2.2

3,417NCT02388165

Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation

Staphylococcus Aureus 4-antigen (SA4Ag) vs Placebo: Number of Participants With Serious Adverse Events (SAEs) From Vaccination Until Day of Surgery (Day 1)27 of 1,708

26 of 1,709

0.1 points

-0.8 to 0.9

3,417NCT02388165

Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation

Staphylococcus Aureus 4-antigen (SA4Ag) vs Placebo: Number of Participants With Serious Adverse Events (SAEs) From The Day of Surgery (Day 1) Until Last Postoperative Evaluation on Day 180384 of 1,708

401 of 1,709

-1.0 points

-3.8 to 1.8

3,417NCT02388165

Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation

Staphylococcus Aureus 4-antigen (SA4Ag) vs Placebo: Number of Participants With Serious Adverse Events (SAEs) From Vaccination Until Last Postoperative Evaluation on Day 180403 of 1,708

424 of 1,709

-1.2 points

-4.1 to 1.7

3,417NCT02388165

Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation

Staphylococcus Aureus 4-antigen (SA4Ag) vs Placebo: Number of Participants With Adverse Events (AEs) From Vaccination Until The Day of Surgery (Day 1)213 of 1,708

178 of 1,709

2.1 points

-0.1 to 4.2

3,417NCT02388165

Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation

Staphylococcus Aureus 4-antigen (SA4Ag) vs Placebo: deaths from any cause13 of 1,708

10 of 1,709

0.2 points

-0.4 to 0.8

3,417NCT02388165

Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation

Staphylococcus Aureus 4-antigen (SA4Ag) vs Placebo: serious adverse events403 of 1,708

424 of 1,709

-1.2 points

-4.1 to 1.7

3,417NCT02388165

Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation

Screening Group vs No Screening: deaths from any cause21 of 1,723

25 of 1,693

-0.3 points

-1.1 to 0.5

3,416NCT01699503

Indiana University Dementia Screening Trial

Screening Group vs No Screening: serious adverse events52 of 1,723

47 of 1,693

0.2 points

-0.9 to 1.4

3,416NCT01699503

Indiana University Dementia Screening Trial

Arm B: Anastrozol - 1 mg Per Day for 5 Years vs Arm A: Anastrozol - 1 mg Per Day for 2 Years: serious adverse events687 of 1,710

452 of 1,705

13.7 points

10.5 to 16.8

3,415NCT00295620

Secondary Adjuvant Long Term Study With Arimidex

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

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Code

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curl "https://conductscience.org/api/comparisons/v1?page=117"

Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=117

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT02235545-sae",
        "title": "Right Ventricle Lead-Related Complications vs Summary of System and/or Procedure Related Complications Not Related to the RV Lead.: serious adverse events",
        "summary": "58 of 1735 against 134 of 1735; risk difference -4.4 points, 95% interval -5.9 to -2.9; NCT02235545, Optisure Lead Post Approval Study",
        "record": "/library/comparisons/NCT02235545-sae",
        "nct_id": "NCT02235545",
        "kind": "serious-adverse-events",
        "participants": 3470,
        "risk_difference": {
          "value": -0.04380403458213256,
          "lower": -0.05925255409388122,
          "upper": -0.028746056541267884
        },
        "group_1": "58 of 1,735",
        "group_2": "134 of 1,735",
        "difference": "-4.4 points",
        "interval": "-5.9 to -2.9",
        "trial_title": "Optisure Lead Post Approval Study"
      },
      {
        "id": "NCT00153101-fea57cf6",
        "title": "Telmisartan (TRANSCEND) vs Placebo (TRANSCEND): TRANSCEND. Newly Diagnosed Diabetes",
        "summary": "124 of 1710 against 165 of 1751; risk difference -2.2 points, 95% interval -4.0 to -0.3; NCT00153101, Effectiveness and Safety of Ramipril Alone Compared With Telmisartan Alone and in Combination With Ramipril in Patients at High Risk for Cardiovascular Events. Patients Intolerant to Ramipril Were Entered in TRANSCEND, Telmisartan Compared to Placebo.",
        "record": "/library/comparisons/NCT00153101-fea57cf6",
        "nct_id": "NCT00153101",
        "kind": "outcome",
        "participants": 3461,
        "risk_difference": {
          "value": -0.02171724762124233,
          "lower": -0.04020344455886146,
          "upper": -0.003270775442302771
        },
        "group_1": "124 of 1,710",
        "group_2": "165 of 1,751",
        "difference": "-2.2 points",
        "interval": "-4.0 to -0.3",
        "trial_title": "Effectiveness and Safety of Ramipril Alone Compared With Telmisartan Alone and in Combination With Ramipril in Patients at High Risk for Cardiovascular Events. Patients Intolerant to Ramipril Were Entered in TRANSCEND, Telmisartan Compared to Placebo."
      }
    ],
    "no_events": 33758,
    "columns": [
      {
        "key": "title",
        "label": "Comparison"
      },
      {
        "key": "group_1",
        "label": "With the outcome",
        "under": "group_2"
      },
      {
        "key": "difference",
        "label": "Risk difference, 95% interval",
        "under": "interval"
      },
      {
        "key": "participants",
        "label": "Participants"
      },
      {
        "key": "nct_id",
        "label": "Trial",
        "under": "trial_title"
      }
    ],
    "order": "Most participants first",
    "kinds": {
      "all": 85013,
      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
    }
  },
  "release": "trial-comparisons-2026-03-23-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "No license stated"
    }
  ],
  "next": "/api/comparisons/v1?page=118",
  "request_id": "JjE_DTKAAVmhR2p-"
}

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About this data
Holds
85,013 comparisons
From ClinicalTrials.gov. Counted 10 Nov 2026.
Release
23 Mar 2026
trial-comparisons-2026-03-23-0.1.0
Checked
20 of 20 review comparisons traced to ClinicalTrials.gov, and all 510,078 numbers calculated again apart from the builder agree
Access
Open
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Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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Every answer on this page is also JSON, under /api/comparisons/v1. No key.

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