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85,013 comparisons from ClinicalTrials.gov.
Most participants first33,758 with no events in either group come last2,321 to 2,340 of 85,013
| Comparison | With the outcome | Risk difference, 95% interval | Participants | Trial |
|---|---|---|---|---|
| Right Ventricle Lead-Related Complications vs Summary of System and/or Procedure Related Complications Not Related to the RV Lead.: serious adverse events | 58 of 1,735 134 of 1,735 | -4.4 points -5.9 to -2.9 | 3,470 | NCT02235545 Optisure Lead Post Approval Study |
| Telmisartan (TRANSCEND) vs Placebo (TRANSCEND): TRANSCEND. Newly Diagnosed Diabetes | 124 of 1,710 165 of 1,751 | -2.2 points -4.0 to -0.3 | 3,461 | NCT00153101 Effectiveness and Safety of Ramipril Alone Compared With Telmisartan Alone and in Combination With Ramipril in Patients at High Risk for Cardiovascular Events. Patients Intolerant to Ramipril Were Entered in TRANSCEND, Telmisartan Compared to Placebo. |
| Group 1: Ad26.RSV.preF and RSV preF Protein vs Group 2: Placebo: Number of Participants With Solicited Systemic AEs up to 7 Days After Vaccination | 1,018 of 2,305 236 of 1,155 | 23.7 points 20.6 to 26.7 | 3,460 | NCT04908683 A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease in Adults Aged 60 Years and Older |
| Group 1: Ad26.RSV.preF and RSV preF Protein vs Group 2: Placebo: Number of Participants With Solicited Local Adverse Events (AEs) up to 7 Days After Vaccination | 1,076 of 2,305 169 of 1,155 | 32.0 points 29.1 to 34.9 | 3,460 | NCT04908683 A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease in Adults Aged 60 Years and Older |
| Spironolactone vs Placebo: serious adverse events | 835 of 1,722 855 of 1,723 | -1.1 points -4.5 to 2.2 | 3,445 | NCT00094302 Aldosterone Antagonist Therapy for Adults With Heart Failure and Preserved Systolic Function |
| IndIndacaterol vs Tiotropium: serious adverse events | 263 of 1,721 255 of 1,718 | 0.4 points -2.0 to 2.8 | 3,439 | NCT00845728 Exacerbation Study |
| Rivaroxaban (Xarelto, BAY59-7939) vs Enoxaparin/VKA: serious adverse events | 222 of 1,718 252 of 1,711 | -1.8 points -4.1 to 0.5 | 3,429 | NCT00440193 Oral Direct Factor Xa Inhibitor Rivaroxaban in Patients With Acute Symptomatic Deep Vein Thrombosis - The EINSTEIN DVT Study |
| Empagliflozin-treated Patients vs Non-SGLT2i-treated Patients: Hospitalizations Due to Heart-failure in the Past 6 Months Before Baseline | 284 of 3,320 6 of 104 | 2.8 points -3.5 to 6.0 | 3,424 | NCT05350202 Emp-Activity: Empagliflozin Functional Capacity |
| Staphylococcus Aureus 4-antigen (SA4Ag) vs Placebo: Number of Participants With Newly Diagnosed Chronic Medical Disorders From First Postoperative Evaluation on Day 42 Until Last Postoperative Evaluation on Day 180 | 29 of 1,708 41 of 1,709 | -0.7 points -1.7 to 0.3 | 3,417 | NCT02388165 Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation |
| Staphylococcus Aureus 4-antigen (SA4Ag) vs Placebo: Number of Participants With Adverse Events (AEs) From The Day of Surgery (Day 1) Until First Postoperative Evaluation on Day 42 | 1,136 of 1,708 1,167 of 1,709 | -1.8 points -4.9 to 1.4 | 3,417 | NCT02388165 Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation |
| Staphylococcus Aureus 4-antigen (SA4Ag) vs Placebo: Number of Participants With Adverse Events (AEs) From Vaccination Until First Postoperative Evaluation on Day 42 | 1,198 of 1,708 1,213 of 1,709 | -0.8 points -3.9 to 2.2 | 3,417 | NCT02388165 Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation |
| Staphylococcus Aureus 4-antigen (SA4Ag) vs Placebo: Number of Participants With Serious Adverse Events (SAEs) From Vaccination Until Day of Surgery (Day 1) | 27 of 1,708 26 of 1,709 | 0.1 points -0.8 to 0.9 | 3,417 | NCT02388165 Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation |
| Staphylococcus Aureus 4-antigen (SA4Ag) vs Placebo: Number of Participants With Serious Adverse Events (SAEs) From The Day of Surgery (Day 1) Until Last Postoperative Evaluation on Day 180 | 384 of 1,708 401 of 1,709 | -1.0 points -3.8 to 1.8 | 3,417 | NCT02388165 Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation |
| Staphylococcus Aureus 4-antigen (SA4Ag) vs Placebo: Number of Participants With Serious Adverse Events (SAEs) From Vaccination Until Last Postoperative Evaluation on Day 180 | 403 of 1,708 424 of 1,709 | -1.2 points -4.1 to 1.7 | 3,417 | NCT02388165 Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation |
| Staphylococcus Aureus 4-antigen (SA4Ag) vs Placebo: Number of Participants With Adverse Events (AEs) From Vaccination Until The Day of Surgery (Day 1) | 213 of 1,708 178 of 1,709 | 2.1 points -0.1 to 4.2 | 3,417 | NCT02388165 Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation |
| Staphylococcus Aureus 4-antigen (SA4Ag) vs Placebo: deaths from any cause | 13 of 1,708 10 of 1,709 | 0.2 points -0.4 to 0.8 | 3,417 | NCT02388165 Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation |
| Staphylococcus Aureus 4-antigen (SA4Ag) vs Placebo: serious adverse events | 403 of 1,708 424 of 1,709 | -1.2 points -4.1 to 1.7 | 3,417 | NCT02388165 Safety and Efficacy of SA4Ag Vaccine in Adults Having Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation |
| Screening Group vs No Screening: deaths from any cause | 21 of 1,723 25 of 1,693 | -0.3 points -1.1 to 0.5 | 3,416 | NCT01699503 Indiana University Dementia Screening Trial |
| Screening Group vs No Screening: serious adverse events | 52 of 1,723 47 of 1,693 | 0.2 points -0.9 to 1.4 | 3,416 | NCT01699503 Indiana University Dementia Screening Trial |
| Arm B: Anastrozol - 1 mg Per Day for 5 Years vs Arm A: Anastrozol - 1 mg Per Day for 2 Years: serious adverse events | 687 of 1,710 452 of 1,705 | 13.7 points 10.5 to 16.8 | 3,415 | NCT00295620 Secondary Adjuvant Long Term Study With Arimidex |
Code
curl "https://conductscience.org/api/comparisons/v1?page=117"
Response
The first 2 of this page's 20 results. GET /api/comparisons/v1?page=117
{
"data": {
"total": 85013,
"results": [
{
"id": "NCT02235545-sae",
"title": "Right Ventricle Lead-Related Complications vs Summary of System and/or Procedure Related Complications Not Related to the RV Lead.: serious adverse events",
"summary": "58 of 1735 against 134 of 1735; risk difference -4.4 points, 95% interval -5.9 to -2.9; NCT02235545, Optisure Lead Post Approval Study",
"record": "/library/comparisons/NCT02235545-sae",
"nct_id": "NCT02235545",
"kind": "serious-adverse-events",
"participants": 3470,
"risk_difference": {
"value": -0.04380403458213256,
"lower": -0.05925255409388122,
"upper": -0.028746056541267884
},
"group_1": "58 of 1,735",
"group_2": "134 of 1,735",
"difference": "-4.4 points",
"interval": "-5.9 to -2.9",
"trial_title": "Optisure Lead Post Approval Study"
},
{
"id": "NCT00153101-fea57cf6",
"title": "Telmisartan (TRANSCEND) vs Placebo (TRANSCEND): TRANSCEND. Newly Diagnosed Diabetes",
"summary": "124 of 1710 against 165 of 1751; risk difference -2.2 points, 95% interval -4.0 to -0.3; NCT00153101, Effectiveness and Safety of Ramipril Alone Compared With Telmisartan Alone and in Combination With Ramipril in Patients at High Risk for Cardiovascular Events. Patients Intolerant to Ramipril Were Entered in TRANSCEND, Telmisartan Compared to Placebo.",
"record": "/library/comparisons/NCT00153101-fea57cf6",
"nct_id": "NCT00153101",
"kind": "outcome",
"participants": 3461,
"risk_difference": {
"value": -0.02171724762124233,
"lower": -0.04020344455886146,
"upper": -0.003270775442302771
},
"group_1": "124 of 1,710",
"group_2": "165 of 1,751",
"difference": "-2.2 points",
"interval": "-4.0 to -0.3",
"trial_title": "Effectiveness and Safety of Ramipril Alone Compared With Telmisartan Alone and in Combination With Ramipril in Patients at High Risk for Cardiovascular Events. Patients Intolerant to Ramipril Were Entered in TRANSCEND, Telmisartan Compared to Placebo."
}
],
"no_events": 33758,
"columns": [
{
"key": "title",
"label": "Comparison"
},
{
"key": "group_1",
"label": "With the outcome",
"under": "group_2"
},
{
"key": "difference",
"label": "Risk difference, 95% interval",
"under": "interval"
},
{
"key": "participants",
"label": "Participants"
},
{
"key": "nct_id",
"label": "Trial",
"under": "trial_title"
}
],
"order": "Most participants first",
"kinds": {
"all": 85013,
"outcome": 33568,
"serious-adverse-events": 31897,
"deaths": 19548
}
},
"release": "trial-comparisons-2026-03-23-0.1.0",
"terms": [
{
"source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
"license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "Freely available. Acknowledgement requested"
},
{
"source": "ClinicalTrials.gov",
"license": "none stated",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "No license stated"
}
],
"next": "/api/comparisons/v1?page=118",
"request_id": "JjE_DTKAAVmhR2p-"
}Ask about these results. The first 10 go in the prompt.
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
NCBI Gene
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For software
Every answer on this page is also JSON, under /api/comparisons/v1. No key.
GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome
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