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85,013 comparisons from ClinicalTrials.gov.

85,013 comparisons

Most participants first33,758 with no events in either group come last4,141 to 4,160 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
C31G Vaginal Gel vs Conceptrol® Vaginal Gel: Incidence of Adverse Events.617 of 932

434 of 633

-2.4 points

-7.0 to 2.4

1,565NCT00274261

Study of the Safety and Contraceptive Efficacy of C31G Compared to Conceptrol®

Idalopirdine 60 mg vs Idalopirdine 60 mg + Memantine: deaths from any cause11 of 1,462

0 of 101

0.8 points

-2.9 to 1.3

1,563NCT02079246

Long-term Safety and Tolerability of Idalopirdine (Lu AE58054) as Adjunctive Treatment to Donepezil in Patients With Mild-moderate Alzheimer's Disease

Idalopirdine 60 mg vs Idalopirdine 60 mg + Memantine: serious adverse events91 of 1,462

2 of 101

4.2 points

-0.8 to 6.2

1,563NCT02079246

Long-term Safety and Tolerability of Idalopirdine (Lu AE58054) as Adjunctive Treatment to Donepezil in Patients With Mild-moderate Alzheimer's Disease

Restrictive Fluids vs Liberal Fluids: serious adverse events18 of 782

19 of 781

-0.1 points

-1.7 to 1.4

1,563NCT03434028

Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis

Pagibaximab vs Placebo: serious adverse events284 of 784

273 of 778

1.1 points

-3.6 to 5.9

1,562NCT00646399

Safety and Efficacy of Pagibaximab Injection in Very Low Birth Weight Neonates for Prevention of Staphylococcal Sepsis

CATCH My Breath (CMB) Program for E-cigarette Prevention Among Adolescents vs Texas Education Agency Required Tobacco Prevention Program: Number of Students Who Are Susceptible to E-cigarette Use357 of 1,034

171 of 528

2.1 points

-2.9 to 7.0

1,562NCT04843501

Middle School Cluster Randomized Controlled Trial (RCT) to Evaluate E-Cigarette Prevention Program: CATCH My Breath

ADACEL® Vaccine Group vs DECAVAC® Vaccine Group: serious adverse events49 of 1,170

20 of 391

-0.9 points

-3.8 to 1.3

1,561NCT00457249

A Trial to Evaluate the Safety and Immunogenicity of ADACEL® Vaccine in Persons 65 Years of Age and Older

Original MMPR - Descending Dose Arm vs MAST MMPR - Escalating Dose Arm: Number of Participants Discharged From the Hospital With an Opioid Prescription527 of 787

476 of 774

5.5 points

0.7 to 10.2

1,561NCT03472469

MAST Trial: Multi-modal Analgesic Strategies in Trauma

Original MMPR - Descending Dose Arm vs MAST MMPR - Escalating Dose Arm: deaths from any cause29 of 787

36 of 774

-1.0 points

-3.0 to 1.0

1,561NCT03472469

MAST Trial: Multi-modal Analgesic Strategies in Trauma

Original MMPR - Descending Dose Arm vs MAST MMPR - Escalating Dose Arm: serious adverse events29 of 787

36 of 774

-1.0 points

-3.0 to 1.0

1,561NCT03472469

MAST Trial: Multi-modal Analgesic Strategies in Trauma

Navigated Care vs Survey of Care: deaths from any cause74 of 1,024

39 of 536

-0.0 points

-2.9 to 2.5

1,560NCT02213458

Care Ecosystem: Navigating Patients and Families Through Stages of Care

Navigated Care vs Survey of Care: serious adverse events269 of 1,024

143 of 536

-0.4 points

-5.1 to 4.1

1,560NCT02213458

Care Ecosystem: Navigating Patients and Families Through Stages of Care

EEG Guided vs Usual Care: deaths from any cause2 of 779

1 of 781

0.1 points

-0.5 to 0.8

1,560NCT03330236

EEG - Guided Anesthetic Care and Postoperative Delirium

IV Rt-PA Cohort vs Non-reperfusion Cohort: deaths from any cause308 of 780

303 of 780

0.6 points

-4.2 to 5.5

1,560NCT05401149

Alteplase Treatment in Elderly Acute Ischaemic Stroke (AIS) Patients

Inclisiran vs Saline Solution: deaths from any cause12 of 781

11 of 778

0.1 points

-1.2 to 1.4

1,559NCT03399370

Inclisiran for Participants With Atherosclerotic Cardiovascular Disease and Elevated Low-density Lipoprotein Cholesterol

Inclisiran vs Saline Solution: serious adverse events175 of 781

205 of 778

-3.9 points

-8.2 to 0.3

1,559NCT03399370

Inclisiran for Participants With Atherosclerotic Cardiovascular Disease and Elevated Low-density Lipoprotein Cholesterol

Restrictive Fluids vs Liberal Fluids: New Onset Atrial or Ventricular Arrhythmia59 of 779

67 of 778

-1.0 points

-3.8 to 1.7

1,557NCT03434028

Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis

Linaclotide (CC) vs Linaclotide (IBS-C): Number of Participants With at Least One Treatment-Emergent Adverse Events (TEAEs)399 of 523

748 of 1,032

3.8 points

-0.8 to 8.3

1,555NCT00765999

An Open-Label, Long-Term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation

Linaclotide (CC) vs Linaclotide (IBS-C): serious adverse events31 of 523

57 of 1,032

0.4 points

-1.9 to 3.1

1,555NCT00765999

An Open-Label, Long-Term Safety Study of Linaclotide in Patients With Chronic Constipation or Irritable Bowel Syndrome With Constipation

Technosphere® Insulin vs Usual Care: FEV1 Decrease of ≥ 15% From Baseline Value at Last Measurement for TI vs Usual Care42 of 730

27 of 824

2.5 points

0.4 to 4.7

1,554NCT00308737

Safety of Inhaled Insulin With Type 1 and Type 2 Diabetes

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

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curl "https://conductscience.org/api/comparisons/v1?page=208"

Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=208

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT00274261-1cfcf389",
        "title": "C31G Vaginal Gel vs Conceptrol® Vaginal Gel: Incidence of Adverse Events.",
        "summary": "617 of 932 against 434 of 633; risk difference -2.4 points, 95% interval -7.0 to 2.4; NCT00274261, Study of the Safety and Contraceptive Efficacy of C31G Compared to Conceptrol®",
        "record": "/library/comparisons/NCT00274261-1cfcf389",
        "nct_id": "NCT00274261",
        "kind": "outcome",
        "participants": 1565,
        "risk_difference": {
          "value": -0.023606845256256448,
          "lower": -0.07031391634254242,
          "upper": 0.023958727873519707
        },
        "group_1": "617 of 932",
        "group_2": "434 of 633",
        "difference": "-2.4 points",
        "interval": "-7.0 to 2.4",
        "trial_title": "Study of the Safety and Contraceptive Efficacy of C31G Compared to Conceptrol®"
      },
      {
        "id": "NCT02079246-deaths",
        "title": "Idalopirdine 60 mg vs Idalopirdine 60 mg + Memantine: deaths from any cause",
        "summary": "11 of 1462 against 0 of 101; risk difference 0.8 points, 95% interval -2.9 to 1.3; NCT02079246, Long-term Safety and Tolerability of Idalopirdine (Lu AE58054) as Adjunctive Treatment to Donepezil in Patients With Mild-moderate Alzheimer's Disease",
        "record": "/library/comparisons/NCT02079246-deaths",
        "nct_id": "NCT02079246",
        "kind": "deaths",
        "participants": 1563,
        "risk_difference": {
          "value": 0.007523939808481532,
          "lower": -0.029266588509199422,
          "upper": 0.013422685523653558
        },
        "group_1": "11 of 1,462",
        "group_2": "0 of 101",
        "difference": "0.8 points",
        "interval": "-2.9 to 1.3",
        "trial_title": "Long-term Safety and Tolerability of Idalopirdine (Lu AE58054) as Adjunctive Treatment to Donepezil in Patients With Mild-moderate Alzheimer's Disease"
      }
    ],
    "no_events": 33758,
    "columns": [
      {
        "key": "title",
        "label": "Comparison"
      },
      {
        "key": "group_1",
        "label": "With the outcome",
        "under": "group_2"
      },
      {
        "key": "difference",
        "label": "Risk difference, 95% interval",
        "under": "interval"
      },
      {
        "key": "participants",
        "label": "Participants"
      },
      {
        "key": "nct_id",
        "label": "Trial",
        "under": "trial_title"
      }
    ],
    "order": "Most participants first",
    "kinds": {
      "all": 85013,
      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
    }
  },
  "release": "trial-comparisons-2026-03-23-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "No license stated"
    }
  ],
  "next": "/api/comparisons/v1?page=209",
  "request_id": "AwtQLs1CgQf8mtEu"
}

Ask about these results. The first 10 go in the prompt.

About this data
Holds
85,013 comparisons
From ClinicalTrials.gov. Counted 10 Nov 2026.
Release
23 Mar 2026
trial-comparisons-2026-03-23-0.1.0
Checked
20 of 20 review comparisons traced to ClinicalTrials.gov, and all 510,078 numbers calculated again apart from the builder agree
Access
Open
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Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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