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One gene with its proteins, patents, drugs, trials, grants and papers.
85,013 comparisons from ClinicalTrials.gov.
Most participants first33,758 with no events in either group come last4,201 to 4,220 of 85,013
| Comparison | With the outcome | Risk difference, 95% interval | Participants | Trial |
|---|---|---|---|---|
| Gepotidacin vs Nitrofurantoin: Number of Participants With Treatment-emergent Adverse Events (TEAEs) | 266 of 766 165 of 760 | 13.0 points 8.5 to 17.4 | 1,526 | NCT04020341 A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI) |
| Gepotidacin vs Nitrofurantoin: Number of Participants With Serious Adverse Events (SAEs) | 2 of 766 3 of 760 | -0.1 points -0.9 to 0.6 | 1,526 | NCT04020341 A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI) |
| Gepotidacin vs Nitrofurantoin: serious adverse events | 2 of 766 3 of 760 | -0.1 points -0.9 to 0.6 | 1,526 | NCT04020341 A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI) |
| Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: Incidence of Protocol-defined Serious or Severe Hypersensitivity Reactions | 3 of 1,019 0 of 506 | 0.3 points -0.5 to 0.9 | 1,525 | NCT02940860 Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for Treatment of Iron Deficiency Anemia in Non-Dialysis-Dependent Chronic Kidney Disease |
| Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: Composite Cardiovascular Adverse Events (AEs) | 42 of 1,019 35 of 506 | -2.8 points -5.6 to -0.4 | 1,525 | NCT02940860 Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for Treatment of Iron Deficiency Anemia in Non-Dialysis-Dependent Chronic Kidney Disease |
| Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: deaths from any cause | 3 of 1,019 3 of 506 | -0.3 points -1.5 to 0.4 | 1,525 | NCT02940860 Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for Treatment of Iron Deficiency Anemia in Non-Dialysis-Dependent Chronic Kidney Disease |
| Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: serious adverse events | 83 of 1,019 50 of 506 | -1.7 points -5.0 to 1.2 | 1,525 | NCT02940860 Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for Treatment of Iron Deficiency Anemia in Non-Dialysis-Dependent Chronic Kidney Disease |
| Remote Blood Pressure Monitoring (rBPM) vs Standard of Care (SOC): deaths from any cause | 0 of 728 1 of 797 | -0.1 points -0.7 to 0.4 | 1,525 | NCT05236725 Monitoring and Testing of Blood Pressure in Postpartum Women |
| Remote Blood Pressure Monitoring (rBPM) vs Standard of Care (SOC): serious adverse events | 34 of 728 26 of 797 | 1.4 points -0.6 to 3.5 | 1,525 | NCT05236725 Monitoring and Testing of Blood Pressure in Postpartum Women |
| Roflumilast vs Placebo: serious adverse events | 144 of 769 153 of 755 | -1.5 points -5.5 to 2.4 | 1,524 | NCT00297102 Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (COPD): The AURA Study (BY217/M2-124) |
| Fluid Restriction Group vs Standard-care: Number of Participants With One or More Serious Adverse Events (SAEs) in the ICU | 221 of 751 238 of 772 | -1.4 points -6.0 to 3.2 | 1,523 | NCT03668236 The Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care Trial |
| Ketamine vs Saline: Number of Participants Who Experienced ICU Transfer | 44 of 770 22 of 752 | 2.8 points 0.7 to 4.9 | 1,522 | NCT04625283 The Impact of Perioperative Ketamine Infusion on Surgical Recovery |
| Ketamine vs Saline: Number of Participants With Ileus | 71 of 770 37 of 752 | 4.3 points 1.7 to 6.9 | 1,522 | NCT04625283 The Impact of Perioperative Ketamine Infusion on Surgical Recovery |
| Ketamine vs Saline: Number of Participants Who Encounter Rapid Response Team Activation | 39 of 770 26 of 752 | 1.6 points -0.4 to 3.7 | 1,522 | NCT04625283 The Impact of Perioperative Ketamine Infusion on Surgical Recovery |
| Ketamine vs Saline: deaths from any cause | 1 of 770 0 of 752 | 0.1 points -0.4 to 0.7 | 1,522 | NCT04625283 The Impact of Perioperative Ketamine Infusion on Surgical Recovery |
| Ketamine vs Saline: serious adverse events | 0 of 770 1 of 752 | -0.1 points -0.7 to 0.4 | 1,522 | NCT04625283 The Impact of Perioperative Ketamine Infusion on Surgical Recovery |
| cSBA - New England, USA vs Control - New England, USA: Any Risky Riding or Driving at 12 Months - New England, USA | 125 of 765 161 of 756 | -5.0 points -8.9 to -1.0 | 1,521 | NCT00227877 Screening and Brief Advice to Reduce Teen Substance Use |
| Boostrix Group vs Adacel Group: Number of Subjects With Anti-tetanus (Anti-T) Antibody Concentrations ≥ Protocol Specified Cut-off | 1,000 of 1,014 504 of 506 | -1.0 points -2.0 to 0.2 | 1,520 | NCT00489970 Persistence Study of GSK Biologicals' Tdap Vaccine 1, 3, 5 and 9 Years Following Administration as an Initial Single Dose in Healthy Young Adults and to Evaluate the Immunogenicity and Safety of Boostrix as a Second Dose of Tdap, When Administered at Year 9 |
| Nevirapine vs Placebo: serious adverse events | 152 of 758 141 of 761 | 1.5 points -2.4 to 5.5 | 1,519 | NCT00074412 Using Nevirapine to Prevent Mother-to-Child HIV Transmission During Breastfeeding |
| Dasatinib vs Placebo: serious adverse events | 381 of 761 317 of 757 | 8.2 points 3.2 to 13.1 | 1,518 | NCT00744497 Randomized Study Comparing Docetaxel Plus Dasatinib to Docetaxel Plus Placebo in Castration-resistant Prostate Cancer |
Code
curl "https://conductscience.org/api/comparisons/v1?page=211"
Response
The first 2 of this page's 20 results. GET /api/comparisons/v1?page=211
{
"data": {
"total": 85013,
"results": [
{
"id": "NCT04020341-6cb4949c",
"title": "Gepotidacin vs Nitrofurantoin: Number of Participants With Treatment-emergent Adverse Events (TEAEs)",
"summary": "266 of 766 against 165 of 760; risk difference 13.0 points, 95% interval 8.5 to 17.4; NCT04020341, A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)",
"record": "/library/comparisons/NCT04020341-6cb4949c",
"nct_id": "NCT04020341",
"kind": "outcome",
"participants": 1526,
"risk_difference": {
"value": 0.13015322248179195,
"lower": 0.08517439898124718,
"upper": 0.17441462179257505
},
"group_1": "266 of 766",
"group_2": "165 of 760",
"difference": "13.0 points",
"interval": "8.5 to 17.4",
"trial_title": "A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)"
},
{
"id": "NCT04020341-ca85f5ef",
"title": "Gepotidacin vs Nitrofurantoin: Number of Participants With Serious Adverse Events (SAEs)",
"summary": "2 of 766 against 3 of 760; risk difference -0.1 points, 95% interval -0.9 to 0.6; NCT04020341, A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)",
"record": "/library/comparisons/NCT04020341-ca85f5ef",
"nct_id": "NCT04020341",
"kind": "outcome",
"participants": 1526,
"risk_difference": {
"value": -0.0013364023636113784,
"lower": -0.009162648299922586,
"upper": 0.005999833245539605
},
"group_1": "2 of 766",
"group_2": "3 of 760",
"difference": "-0.1 points",
"interval": "-0.9 to 0.6",
"trial_title": "A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)"
}
],
"no_events": 33758,
"columns": [
{
"key": "title",
"label": "Comparison"
},
{
"key": "group_1",
"label": "With the outcome",
"under": "group_2"
},
{
"key": "difference",
"label": "Risk difference, 95% interval",
"under": "interval"
},
{
"key": "participants",
"label": "Participants"
},
{
"key": "nct_id",
"label": "Trial",
"under": "trial_title"
}
],
"order": "Most participants first",
"kinds": {
"all": 85013,
"outcome": 33568,
"serious-adverse-events": 31897,
"deaths": 19548
}
},
"release": "trial-comparisons-2026-03-23-0.1.0",
"terms": [
{
"source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
"license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "Freely available. Acknowledgement requested"
},
{
"source": "ClinicalTrials.gov",
"license": "none stated",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "No license stated"
}
],
"next": "/api/comparisons/v1?page=212",
"request_id": "El5OiJ1i4UIKgYZr"
}Ask about these results. The first 10 go in the prompt.
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
NCBI Gene
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For software
Every answer on this page is also JSON, under /api/comparisons/v1. No key.
GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome
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