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85,013 comparisons from ClinicalTrials.gov.

85,013 comparisons

Most participants first33,758 with no events in either group come last4,201 to 4,220 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
Gepotidacin vs Nitrofurantoin: Number of Participants With Treatment-emergent Adverse Events (TEAEs)266 of 766

165 of 760

13.0 points

8.5 to 17.4

1,526NCT04020341

A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)

Gepotidacin vs Nitrofurantoin: Number of Participants With Serious Adverse Events (SAEs)2 of 766

3 of 760

-0.1 points

-0.9 to 0.6

1,526NCT04020341

A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)

Gepotidacin vs Nitrofurantoin: serious adverse events2 of 766

3 of 760

-0.1 points

-0.9 to 0.6

1,526NCT04020341

A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: Incidence of Protocol-defined Serious or Severe Hypersensitivity Reactions3 of 1,019

0 of 506

0.3 points

-0.5 to 0.9

1,525NCT02940860

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for Treatment of Iron Deficiency Anemia in Non-Dialysis-Dependent Chronic Kidney Disease

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: Composite Cardiovascular Adverse Events (AEs)42 of 1,019

35 of 506

-2.8 points

-5.6 to -0.4

1,525NCT02940860

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for Treatment of Iron Deficiency Anemia in Non-Dialysis-Dependent Chronic Kidney Disease

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: deaths from any cause3 of 1,019

3 of 506

-0.3 points

-1.5 to 0.4

1,525NCT02940860

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for Treatment of Iron Deficiency Anemia in Non-Dialysis-Dependent Chronic Kidney Disease

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: serious adverse events83 of 1,019

50 of 506

-1.7 points

-5.0 to 1.2

1,525NCT02940860

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for Treatment of Iron Deficiency Anemia in Non-Dialysis-Dependent Chronic Kidney Disease

Remote Blood Pressure Monitoring (rBPM) vs Standard of Care (SOC): deaths from any cause0 of 728

1 of 797

-0.1 points

-0.7 to 0.4

1,525NCT05236725

Monitoring and Testing of Blood Pressure in Postpartum Women

Remote Blood Pressure Monitoring (rBPM) vs Standard of Care (SOC): serious adverse events34 of 728

26 of 797

1.4 points

-0.6 to 3.5

1,525NCT05236725

Monitoring and Testing of Blood Pressure in Postpartum Women

Roflumilast vs Placebo: serious adverse events144 of 769

153 of 755

-1.5 points

-5.5 to 2.4

1,524NCT00297102

Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (COPD): The AURA Study (BY217/M2-124)

Fluid Restriction Group vs Standard-care: Number of Participants With One or More Serious Adverse Events (SAEs) in the ICU221 of 751

238 of 772

-1.4 points

-6.0 to 3.2

1,523NCT03668236

The Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care Trial

Ketamine vs Saline: Number of Participants Who Experienced ICU Transfer44 of 770

22 of 752

2.8 points

0.7 to 4.9

1,522NCT04625283

The Impact of Perioperative Ketamine Infusion on Surgical Recovery

Ketamine vs Saline: Number of Participants With Ileus71 of 770

37 of 752

4.3 points

1.7 to 6.9

1,522NCT04625283

The Impact of Perioperative Ketamine Infusion on Surgical Recovery

Ketamine vs Saline: Number of Participants Who Encounter Rapid Response Team Activation39 of 770

26 of 752

1.6 points

-0.4 to 3.7

1,522NCT04625283

The Impact of Perioperative Ketamine Infusion on Surgical Recovery

Ketamine vs Saline: deaths from any cause1 of 770

0 of 752

0.1 points

-0.4 to 0.7

1,522NCT04625283

The Impact of Perioperative Ketamine Infusion on Surgical Recovery

Ketamine vs Saline: serious adverse events0 of 770

1 of 752

-0.1 points

-0.7 to 0.4

1,522NCT04625283

The Impact of Perioperative Ketamine Infusion on Surgical Recovery

cSBA - New England, USA vs Control - New England, USA: Any Risky Riding or Driving at 12 Months - New England, USA125 of 765

161 of 756

-5.0 points

-8.9 to -1.0

1,521NCT00227877

Screening and Brief Advice to Reduce Teen Substance Use

Boostrix Group vs Adacel Group: Number of Subjects With Anti-tetanus (Anti-T) Antibody Concentrations ≥ Protocol Specified Cut-off1,000 of 1,014

504 of 506

-1.0 points

-2.0 to 0.2

1,520NCT00489970

Persistence Study of GSK Biologicals' Tdap Vaccine 1, 3, 5 and 9 Years Following Administration as an Initial Single Dose in Healthy Young Adults and to Evaluate the Immunogenicity and Safety of Boostrix as a Second Dose of Tdap, When Administered at Year 9

Nevirapine vs Placebo: serious adverse events152 of 758

141 of 761

1.5 points

-2.4 to 5.5

1,519NCT00074412

Using Nevirapine to Prevent Mother-to-Child HIV Transmission During Breastfeeding

Dasatinib vs Placebo: serious adverse events381 of 761

317 of 757

8.2 points

3.2 to 13.1

1,518NCT00744497

Randomized Study Comparing Docetaxel Plus Dasatinib to Docetaxel Plus Placebo in Castration-resistant Prostate Cancer

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

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Code

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curl "https://conductscience.org/api/comparisons/v1?page=211"

Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=211

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT04020341-6cb4949c",
        "title": "Gepotidacin vs Nitrofurantoin: Number of Participants With Treatment-emergent Adverse Events (TEAEs)",
        "summary": "266 of 766 against 165 of 760; risk difference 13.0 points, 95% interval 8.5 to 17.4; NCT04020341, A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)",
        "record": "/library/comparisons/NCT04020341-6cb4949c",
        "nct_id": "NCT04020341",
        "kind": "outcome",
        "participants": 1526,
        "risk_difference": {
          "value": 0.13015322248179195,
          "lower": 0.08517439898124718,
          "upper": 0.17441462179257505
        },
        "group_1": "266 of 766",
        "group_2": "165 of 760",
        "difference": "13.0 points",
        "interval": "8.5 to 17.4",
        "trial_title": "A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)"
      },
      {
        "id": "NCT04020341-ca85f5ef",
        "title": "Gepotidacin vs Nitrofurantoin: Number of Participants With Serious Adverse Events (SAEs)",
        "summary": "2 of 766 against 3 of 760; risk difference -0.1 points, 95% interval -0.9 to 0.6; NCT04020341, A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)",
        "record": "/library/comparisons/NCT04020341-ca85f5ef",
        "nct_id": "NCT04020341",
        "kind": "outcome",
        "participants": 1526,
        "risk_difference": {
          "value": -0.0013364023636113784,
          "lower": -0.009162648299922586,
          "upper": 0.005999833245539605
        },
        "group_1": "2 of 766",
        "group_2": "3 of 760",
        "difference": "-0.1 points",
        "interval": "-0.9 to 0.6",
        "trial_title": "A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)"
      }
    ],
    "no_events": 33758,
    "columns": [
      {
        "key": "title",
        "label": "Comparison"
      },
      {
        "key": "group_1",
        "label": "With the outcome",
        "under": "group_2"
      },
      {
        "key": "difference",
        "label": "Risk difference, 95% interval",
        "under": "interval"
      },
      {
        "key": "participants",
        "label": "Participants"
      },
      {
        "key": "nct_id",
        "label": "Trial",
        "under": "trial_title"
      }
    ],
    "order": "Most participants first",
    "kinds": {
      "all": 85013,
      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
    }
  },
  "release": "trial-comparisons-2026-03-23-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "No license stated"
    }
  ],
  "next": "/api/comparisons/v1?page=212",
  "request_id": "El5OiJ1i4UIKgYZr"
}

Ask about these results. The first 10 go in the prompt.

About this data
Holds
85,013 comparisons
From ClinicalTrials.gov. Counted 10 Nov 2026.
Release
23 Mar 2026
trial-comparisons-2026-03-23-0.1.0
Checked
20 of 20 review comparisons traced to ClinicalTrials.gov, and all 510,078 numbers calculated again apart from the builder agree
Access
Open
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Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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