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85,013 comparisons from ClinicalTrials.gov.
Most participants first33,758 with no events in either group come last4,301 to 4,320 of 85,013
| Comparison | With the outcome | Risk difference, 95% interval | Participants | Trial |
|---|---|---|---|---|
| Trastuzumab vs Trastuzumab Emtansine: deaths from any cause | 126 of 743 94 of 743 | 4.3 points 0.7 to 7.9 | 1,486 | NCT01772472 A Study of Trastuzumab Emtansine Versus Trastuzumab as Adjuvant Therapy in Patients With HER2-Positive Breast Cancer Who Have Residual Tumor in the Breast or Axillary Lymph Nodes Following Preoperative Therapy (KATHERINE) |
| Edoxaban Regimen vs Vitamin K Antagonist Regimen: deaths from any cause | 46 of 746 37 of 740 | 1.2 points -1.2 to 3.5 | 1,486 | NCT02866175 Edoxaban Treatment Versus Vitamin K Antagonist in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention |
| Edoxaban Regimen vs Vitamin K Antagonist Regimen: serious adverse events | 176 of 746 175 of 740 | -0.1 points -4.4 to 4.3 | 1,486 | NCT02866175 Edoxaban Treatment Versus Vitamin K Antagonist in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention |
| NB32/48 vs Placebo: serious adverse events | 21 of 992 7 of 492 | 0.7 points -1.0 to 2.0 | 1,484 | NCT00567255 A Safety and Efficacy Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects |
| FMX101, 4% Minocycline Foam vs Vehicle Foam: serious adverse events | 1 of 737 4 of 747 | -0.4 points -1.2 to 0.3 | 1,484 | NCT03271021 A Study to Evaluate the Efficacy and Safety of Topical Administration of FMX101 in the Treatment of Moderate-to-Severe Acne Vulgaris |
| Phase 3 Cohort 1 (1.2g IV) >= 18 vs Phase 3 Cohort 1 (Placebo) >=18: Proportion of Participants With ≥1 COVID-19-related Hospitalization, Emergency Room Visit, or All-cause Death (Ph3 Cohort 1) - Placebo vs. 1.2g IV | 20 of 736 51 of 748 | -4.1 points -6.3 to -2.0 | 1,484 | NCT04425629 Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for the Treatment of Ambulatory Adult and Pediatric Patients With COVID-19 |
| Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: Incidence of Protocol-defined Serious or Severe Hypersensitivity Reactions | 3 of 989 2 of 494 | -0.1 points -1.2 to 0.6 | 1,483 | NCT02940886 Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for the Treatment of Iron Deficiency Anemia (IDA) |
| Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: S-phosphate <2 mg/dL at Any Time From Baseline to Week 1, 2, 4, and 8 | 38 of 989 11 of 494 | 1.6 points -0.4 to 3.3 | 1,483 | NCT02940886 Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for the Treatment of Iron Deficiency Anemia (IDA) |
| Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: Composite Cardiovascular Adverse Events (AEs) | 8 of 989 6 of 494 | -0.4 points -1.9 to 0.6 | 1,483 | NCT02940886 Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for the Treatment of Iron Deficiency Anemia (IDA) |
| Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: deaths from any cause | 1 of 989 0 of 494 | 0.1 points -0.7 to 0.6 | 1,483 | NCT02940886 Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for the Treatment of Iron Deficiency Anemia (IDA) |
| Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: serious adverse events | 21 of 989 13 of 494 | -0.5 points -2.5 to 1.0 | 1,483 | NCT02940886 Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for the Treatment of Iron Deficiency Anemia (IDA) |
| Phase 3 Cohort 1 (1.2g IV) >= 18 vs Phase 3 Cohort 1 (Placebo) >=18: Proportion of Participants With ≥1 COVID-19-related Hospitalization or All-cause Death From Day 4 Through Day 29 (Ph3 Cohort 1 - 1.2g vs. Placebo) | 18 of 748 5 of 735 | 1.7 points 0.5 to 3.1 | 1,483 | NCT04425629 Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for the Treatment of Ambulatory Adult and Pediatric Patients With COVID-19 |
| TAS x 8 Weeks vs TAS x 28 Weeks: serious adverse events | 121 of 747 109 of 735 | 1.4 points -2.3 to 5.1 | 1,482 | NCT00005044 Hormone Therapy and Radiation Therapy in Treating Patients With Prostate Cancer |
| 70.2 Gy vs 79.2 Gy: serious adverse events | 30 of 744 43 of 737 | -1.8 points -4.1 to 0.4 | 1,481 | NCT00033631 Radiation Therapy in Treating Patients With Stage II Prostate Cancer |
| MK-8237 vs Placebo: Number of Participants Who Discontinue Study Drug Due to an AE | 73 of 743 19 of 738 | 7.3 points 4.9 to 9.8 | 1,481 | NCT01700192 Efficacy and Safety Study of SCH 900237/MK-8237 in Children and Adults With House Dust Mite-Induced Allergic Rhinitis/Rhinoconjunctivitis (P05607) |
| MK-8237 vs Placebo: Number of Participants Who Experience At Least One Adverse Event (AE) | 676 of 743 539 of 738 | 17.9 points 14.1 to 21.7 | 1,481 | NCT01700192 Efficacy and Safety Study of SCH 900237/MK-8237 in Children and Adults With House Dust Mite-Induced Allergic Rhinitis/Rhinoconjunctivitis (P05607) |
| MK-8237 12 DU vs Placebo: serious adverse events | 11 of 743 7 of 738 | 0.5 points -0.7 to 1.8 | 1,481 | NCT01700192 Efficacy and Safety Study of SCH 900237/MK-8237 in Children and Adults With House Dust Mite-Induced Allergic Rhinitis/Rhinoconjunctivitis (P05607) |
| TAC (Docetaxel) vs FAC (5-fluorouracil): serious adverse events | 267 of 744 67 of 736 | 26.8 points 22.7 to 30.8 | 1,480 | NCT00688740 Docetaxel in Node Positive Adjuvant Breast Cancer |
| Retrospective vs Prospective: Diagnosis of Pulmonary Hypertension Diagnosis | 0 of 991 1 of 489 | -0.2 points -1.1 to 0.2 | 1,480 | NCT03426124 An International Pulmonary Embolism Registry Using EKOS |
| Retrospective vs Prospective: All-cause Mortality During First 12 Months Post-procedure. | 50 of 991 15 of 489 | 2.0 points -0.3 to 3.9 | 1,480 | NCT03426124 An International Pulmonary Embolism Registry Using EKOS |
Code
curl "https://conductscience.org/api/comparisons/v1?page=216"
Response
The first 2 of this page's 20 results. GET /api/comparisons/v1?page=216
{
"data": {
"total": 85013,
"results": [
{
"id": "NCT01772472-deaths",
"title": "Trastuzumab vs Trastuzumab Emtansine: deaths from any cause",
"summary": "126 of 743 against 94 of 743; risk difference 4.3 points, 95% interval 0.7 to 7.9; NCT01772472, A Study of Trastuzumab Emtansine Versus Trastuzumab as Adjuvant Therapy in Patients With HER2-Positive Breast Cancer Who Have Residual Tumor in the Breast or Axillary Lymph Nodes Following Preoperative Therapy (KATHERINE)",
"record": "/library/comparisons/NCT01772472-deaths",
"nct_id": "NCT01772472",
"kind": "deaths",
"participants": 1486,
"risk_difference": {
"value": 0.04306864064602961,
"lower": 0.006927949834620084,
"upper": 0.07920283408365097
},
"group_1": "126 of 743",
"group_2": "94 of 743",
"difference": "4.3 points",
"interval": "0.7 to 7.9",
"trial_title": "A Study of Trastuzumab Emtansine Versus Trastuzumab as Adjuvant Therapy in Patients With HER2-Positive Breast Cancer Who Have Residual Tumor in the Breast or Axillary Lymph Nodes Following Preoperative Therapy (KATHERINE)"
},
{
"id": "NCT02866175-deaths",
"title": "Edoxaban Regimen vs Vitamin K Antagonist Regimen: deaths from any cause",
"summary": "46 of 746 against 37 of 740; risk difference 1.2 points, 95% interval -1.2 to 3.5; NCT02866175, Edoxaban Treatment Versus Vitamin K Antagonist in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention",
"record": "/library/comparisons/NCT02866175-deaths",
"nct_id": "NCT02866175",
"kind": "deaths",
"participants": 1486,
"risk_difference": {
"value": 0.011662198391420908,
"lower": -0.011964616657909561,
"upper": 0.03547391470628197
},
"group_1": "46 of 746",
"group_2": "37 of 740",
"difference": "1.2 points",
"interval": "-1.2 to 3.5",
"trial_title": "Edoxaban Treatment Versus Vitamin K Antagonist in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention"
}
],
"no_events": 33758,
"columns": [
{
"key": "title",
"label": "Comparison"
},
{
"key": "group_1",
"label": "With the outcome",
"under": "group_2"
},
{
"key": "difference",
"label": "Risk difference, 95% interval",
"under": "interval"
},
{
"key": "participants",
"label": "Participants"
},
{
"key": "nct_id",
"label": "Trial",
"under": "trial_title"
}
],
"order": "Most participants first",
"kinds": {
"all": 85013,
"outcome": 33568,
"serious-adverse-events": 31897,
"deaths": 19548
}
},
"release": "trial-comparisons-2026-03-23-0.1.0",
"terms": [
{
"source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
"license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "Freely available. Acknowledgement requested"
},
{
"source": "ClinicalTrials.gov",
"license": "none stated",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "No license stated"
}
],
"next": "/api/comparisons/v1?page=217",
"request_id": "XI_h9KIBxUFMan6f"
}Ask about these results. The first 10 go in the prompt.
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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