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85,013 comparisons from ClinicalTrials.gov.

85,013 comparisons

Most participants first33,758 with no events in either group come last4,301 to 4,320 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
Trastuzumab vs Trastuzumab Emtansine: deaths from any cause126 of 743

94 of 743

4.3 points

0.7 to 7.9

1,486NCT01772472

A Study of Trastuzumab Emtansine Versus Trastuzumab as Adjuvant Therapy in Patients With HER2-Positive Breast Cancer Who Have Residual Tumor in the Breast or Axillary Lymph Nodes Following Preoperative Therapy (KATHERINE)

Edoxaban Regimen vs Vitamin K Antagonist Regimen: deaths from any cause46 of 746

37 of 740

1.2 points

-1.2 to 3.5

1,486NCT02866175

Edoxaban Treatment Versus Vitamin K Antagonist in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention

Edoxaban Regimen vs Vitamin K Antagonist Regimen: serious adverse events176 of 746

175 of 740

-0.1 points

-4.4 to 4.3

1,486NCT02866175

Edoxaban Treatment Versus Vitamin K Antagonist in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention

NB32/48 vs Placebo: serious adverse events21 of 992

7 of 492

0.7 points

-1.0 to 2.0

1,484NCT00567255

A Safety and Efficacy Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects

FMX101, 4% Minocycline Foam vs Vehicle Foam: serious adverse events1 of 737

4 of 747

-0.4 points

-1.2 to 0.3

1,484NCT03271021

A Study to Evaluate the Efficacy and Safety of Topical Administration of FMX101 in the Treatment of Moderate-to-Severe Acne Vulgaris

Phase 3 Cohort 1 (1.2g IV) >= 18 vs Phase 3 Cohort 1 (Placebo) >=18: Proportion of Participants With ≥1 COVID-19-related Hospitalization, Emergency Room Visit, or All-cause Death (Ph3 Cohort 1) - Placebo vs. 1.2g IV20 of 736

51 of 748

-4.1 points

-6.3 to -2.0

1,484NCT04425629

Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for the Treatment of Ambulatory Adult and Pediatric Patients With COVID-19

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: Incidence of Protocol-defined Serious or Severe Hypersensitivity Reactions3 of 989

2 of 494

-0.1 points

-1.2 to 0.6

1,483NCT02940886

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for the Treatment of Iron Deficiency Anemia (IDA)

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: S-phosphate <2 mg/dL at Any Time From Baseline to Week 1, 2, 4, and 838 of 989

11 of 494

1.6 points

-0.4 to 3.3

1,483NCT02940886

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for the Treatment of Iron Deficiency Anemia (IDA)

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: Composite Cardiovascular Adverse Events (AEs)8 of 989

6 of 494

-0.4 points

-1.9 to 0.6

1,483NCT02940886

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for the Treatment of Iron Deficiency Anemia (IDA)

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: deaths from any cause1 of 989

0 of 494

0.1 points

-0.7 to 0.6

1,483NCT02940886

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for the Treatment of Iron Deficiency Anemia (IDA)

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose: serious adverse events21 of 989

13 of 494

-0.5 points

-2.5 to 1.0

1,483NCT02940886

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for the Treatment of Iron Deficiency Anemia (IDA)

Phase 3 Cohort 1 (1.2g IV) >= 18 vs Phase 3 Cohort 1 (Placebo) >=18: Proportion of Participants With ≥1 COVID-19-related Hospitalization or All-cause Death From Day 4 Through Day 29 (Ph3 Cohort 1 - 1.2g vs. Placebo)18 of 748

5 of 735

1.7 points

0.5 to 3.1

1,483NCT04425629

Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for the Treatment of Ambulatory Adult and Pediatric Patients With COVID-19

TAS x 8 Weeks vs TAS x 28 Weeks: serious adverse events121 of 747

109 of 735

1.4 points

-2.3 to 5.1

1,482NCT00005044

Hormone Therapy and Radiation Therapy in Treating Patients With Prostate Cancer

70.2 Gy vs 79.2 Gy: serious adverse events30 of 744

43 of 737

-1.8 points

-4.1 to 0.4

1,481NCT00033631

Radiation Therapy in Treating Patients With Stage II Prostate Cancer

MK-8237 vs Placebo: Number of Participants Who Discontinue Study Drug Due to an AE73 of 743

19 of 738

7.3 points

4.9 to 9.8

1,481NCT01700192

Efficacy and Safety Study of SCH 900237/MK-8237 in Children and Adults With House Dust Mite-Induced Allergic Rhinitis/Rhinoconjunctivitis (P05607)

MK-8237 vs Placebo: Number of Participants Who Experience At Least One Adverse Event (AE)676 of 743

539 of 738

17.9 points

14.1 to 21.7

1,481NCT01700192

Efficacy and Safety Study of SCH 900237/MK-8237 in Children and Adults With House Dust Mite-Induced Allergic Rhinitis/Rhinoconjunctivitis (P05607)

MK-8237 12 DU vs Placebo: serious adverse events11 of 743

7 of 738

0.5 points

-0.7 to 1.8

1,481NCT01700192

Efficacy and Safety Study of SCH 900237/MK-8237 in Children and Adults With House Dust Mite-Induced Allergic Rhinitis/Rhinoconjunctivitis (P05607)

TAC (Docetaxel) vs FAC (5-fluorouracil): serious adverse events267 of 744

67 of 736

26.8 points

22.7 to 30.8

1,480NCT00688740

Docetaxel in Node Positive Adjuvant Breast Cancer

Retrospective vs Prospective: Diagnosis of Pulmonary Hypertension Diagnosis0 of 991

1 of 489

-0.2 points

-1.1 to 0.2

1,480NCT03426124

An International Pulmonary Embolism Registry Using EKOS

Retrospective vs Prospective: All-cause Mortality During First 12 Months Post-procedure.50 of 991

15 of 489

2.0 points

-0.3 to 3.9

1,480NCT03426124

An International Pulmonary Embolism Registry Using EKOS

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

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Code

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curl "https://conductscience.org/api/comparisons/v1?page=216"

Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=216

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT01772472-deaths",
        "title": "Trastuzumab vs Trastuzumab Emtansine: deaths from any cause",
        "summary": "126 of 743 against 94 of 743; risk difference 4.3 points, 95% interval 0.7 to 7.9; NCT01772472, A Study of Trastuzumab Emtansine Versus Trastuzumab as Adjuvant Therapy in Patients With HER2-Positive Breast Cancer Who Have Residual Tumor in the Breast or Axillary Lymph Nodes Following Preoperative Therapy (KATHERINE)",
        "record": "/library/comparisons/NCT01772472-deaths",
        "nct_id": "NCT01772472",
        "kind": "deaths",
        "participants": 1486,
        "risk_difference": {
          "value": 0.04306864064602961,
          "lower": 0.006927949834620084,
          "upper": 0.07920283408365097
        },
        "group_1": "126 of 743",
        "group_2": "94 of 743",
        "difference": "4.3 points",
        "interval": "0.7 to 7.9",
        "trial_title": "A Study of Trastuzumab Emtansine Versus Trastuzumab as Adjuvant Therapy in Patients With HER2-Positive Breast Cancer Who Have Residual Tumor in the Breast or Axillary Lymph Nodes Following Preoperative Therapy (KATHERINE)"
      },
      {
        "id": "NCT02866175-deaths",
        "title": "Edoxaban Regimen vs Vitamin K Antagonist Regimen: deaths from any cause",
        "summary": "46 of 746 against 37 of 740; risk difference 1.2 points, 95% interval -1.2 to 3.5; NCT02866175, Edoxaban Treatment Versus Vitamin K Antagonist in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention",
        "record": "/library/comparisons/NCT02866175-deaths",
        "nct_id": "NCT02866175",
        "kind": "deaths",
        "participants": 1486,
        "risk_difference": {
          "value": 0.011662198391420908,
          "lower": -0.011964616657909561,
          "upper": 0.03547391470628197
        },
        "group_1": "46 of 746",
        "group_2": "37 of 740",
        "difference": "1.2 points",
        "interval": "-1.2 to 3.5",
        "trial_title": "Edoxaban Treatment Versus Vitamin K Antagonist in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention"
      }
    ],
    "no_events": 33758,
    "columns": [
      {
        "key": "title",
        "label": "Comparison"
      },
      {
        "key": "group_1",
        "label": "With the outcome",
        "under": "group_2"
      },
      {
        "key": "difference",
        "label": "Risk difference, 95% interval",
        "under": "interval"
      },
      {
        "key": "participants",
        "label": "Participants"
      },
      {
        "key": "nct_id",
        "label": "Trial",
        "under": "trial_title"
      }
    ],
    "order": "Most participants first",
    "kinds": {
      "all": 85013,
      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
    }
  },
  "release": "trial-comparisons-2026-03-23-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "No license stated"
    }
  ],
  "next": "/api/comparisons/v1?page=217",
  "request_id": "XI_h9KIBxUFMan6f"
}

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About this data
Holds
85,013 comparisons
From ClinicalTrials.gov. Counted 10 Nov 2026.
Release
23 Mar 2026
trial-comparisons-2026-03-23-0.1.0
Checked
20 of 20 review comparisons traced to ClinicalTrials.gov, and all 510,078 numbers calculated again apart from the builder agree
Access
Open
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Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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