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85,013 comparisons from ClinicalTrials.gov.

85,013 comparisons

Most participants first33,758 with no events in either group come last4,381 to 4,400 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
Home Monitoring vs Conventional: serious adverse events124 of 977

74 of 473

-3.0 points

-7.0 to 0.8

1,450NCT00336284

TRUST: Lumos-T Safely RedUceS RouTine Office Device Follow-up

Sodium Hyaluronate vs Vehicle: serious adverse events1 of 723

1 of 727

0.0 points

-0.6 to 0.7

1,450NCT01382225

Sodium Hyaluronate Ophthalmic Solution, 0.18% for Treatment of Dry Eye Syndrome

Cohort 1 vs Cohort 2: Number of Participants With Tacrolimus-related Neurotoxicities10 of 819

1 of 631

1.1 points

0.1 to 2.1

1,450NCT03083769

Functional Genetic Variants Affecting Tacrolimus Trough Levels and Side Effects in Chinese Renal Transplantation.

Cohort 1 vs Cohort 2: Number of Participants With Acute Rejection256 of 819

37 of 631

25.4 points

21.7 to 29.0

1,450NCT03083769

Functional Genetic Variants Affecting Tacrolimus Trough Levels and Side Effects in Chinese Renal Transplantation.

Cohort 1 vs Cohort 2: Number of Participants With Tacrolimus-related Nephrotoxicities26 of 819

2 of 631

2.9 points

1.6 to 4.3

1,450NCT03083769

Functional Genetic Variants Affecting Tacrolimus Trough Levels and Side Effects in Chinese Renal Transplantation.

Cohort 1 vs Cohort 2: serious adverse events256 of 819

37 of 631

25.4 points

21.7 to 29.0

1,450NCT03083769

Functional Genetic Variants Affecting Tacrolimus Trough Levels and Side Effects in Chinese Renal Transplantation.

Telmisartan 40mg and Amlodipine 10mg vs Telmisartan 80mg and Amlodipine 10mg: serious adverse events4 of 838

13 of 611

-1.7 points

-3.2 to -0.5

1,449NCT00624052

26-week Open Study of telmisartan40mg+amlodipine10mg or telmisartan80mg+amlodipine10 mg in Hypertension

Placebo: IPs vs Baloxavir Marboxil: IPs: Number of IPs With Serious Adverse Events (SAEs)2 of 726

1 of 723

0.1 points

-0.5 to 0.9

1,449NCT03969212

Study to Assess the Efficacy of Baloxavir Marboxil Versus Placebo to Reduce Onward Transmission of Influenza A or B in Households

Placebo: IPs vs Baloxavir Marboxil: IPs: Number of IPs With Adverse Events (AEs)51 of 726

33 of 723

2.5 points

0.0 to 4.9

1,449NCT03969212

Study to Assess the Efficacy of Baloxavir Marboxil Versus Placebo to Reduce Onward Transmission of Influenza A or B in Households

Placebo: IPs vs Baloxavir Marboxil: IPs: serious adverse events2 of 726

1 of 723

0.1 points

-0.5 to 0.9

1,449NCT03969212

Study to Assess the Efficacy of Baloxavir Marboxil Versus Placebo to Reduce Onward Transmission of Influenza A or B in Households

Combination of ARB and ACEI vs Monotherapy ARB: A Composite Endpoint of Reduction in Estimated GFR of 30ml/Min/1.73m*m in Individuals w/a Baseline Estimated GFR >= 60 ml/Min/1.73m*m, Reduction in Estimated GFR >50% in Individuals w/ Baseline Estimated GFR <60ml/Min/1.73m*m; ESRD or Death132 of 724

152 of 724

-2.8 points

-6.8 to 1.3

1,448NCT00555217

VA NEPHRON-D: Diabetes iN Nephropathy Study

Combination of ARB and ACEI vs Monotherapy ARB: A Renal Composite Endpoint, Defined as; Reduction in Estimated GFR of >50% (for Individuals With Baseline GFR <60) or Reduction in GFR of >30 (for Individuals With Baseline GFR >= GFR 60) or ESRD.77 of 724

101 of 724

-3.3 points

-6.7 to 0.1

1,448NCT00555217

VA NEPHRON-D: Diabetes iN Nephropathy Study

Combination of ARB and ACEI vs Monotherapy ARB: serious adverse events416 of 724

380 of 724

5.0 points

-0.2 to 10.1

1,448NCT00555217

VA NEPHRON-D: Diabetes iN Nephropathy Study

EP2006: Any CIN/FN-related Chemotherapy Disturbance vs EP2006: no CIN/FN-related Chemotherapy Disturbance: Number of Participants With All-cause Mortality by CIN/FN-related Chemotherapy Disturbance3 of 138

53 of 1,309

-1.9 points

-3.7 to 2.3

1,447NCT01459653

Multi-level Evaluation of Chemotherapy-induced Febrile Neutropenia Prophylaxis, Outcomes, and Determinants With Granulocyte-colony Stimulating Factor

EP2006: Primary Prophylaxis vs EP2006: Secondary Prophylaxis: Number of Participants With Any CIN/FN-related Chemotherapy Disturbance by Prophylaxis Type78 of 1,046

60 of 401

-7.5 points

-11.6 to -3.9

1,447NCT01459653

Multi-level Evaluation of Chemotherapy-induced Febrile Neutropenia Prophylaxis, Outcomes, and Determinants With Granulocyte-colony Stimulating Factor

EP2006: Any Grade 4 CIN/FN vs EP2006: No Grade 4 CIN/FN: Number of Participants With All-cause Mortality by Any/no Grade 4 CIN and/or FN10 of 221

46 of 1,226

0.8 points

-1.6 to 4.5

1,447NCT01459653

Multi-level Evaluation of Chemotherapy-induced Febrile Neutropenia Prophylaxis, Outcomes, and Determinants With Granulocyte-colony Stimulating Factor

MEDI8897 50 mg vs Placebo: deaths from any cause2 of 968

3 of 479

-0.4 points

-1.6 to 0.3

1,447NCT02878330

A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended RSV LRTI in Healthy Preterm Infants.

MEDI8897 50 mg vs Placebo: serious adverse events108 of 968

81 of 479

-5.8 points

-9.8 to -2.0

1,447NCT02878330

A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended RSV LRTI in Healthy Preterm Infants.

Regional Anesthesia vs General Anesthesia: Death or Inability to Walk 10 Feet or Across a Room Without Human Assistance132 of 712

132 of 733

0.5 points

-3.5 to 4.5

1,445NCT02507505

Regional Versus General Anesthesia for Promoting Independence After Hip Fracture

Tolvaptan vs Placebo: serious adverse events177 of 961

95 of 483

-1.3 points

-5.7 to 2.9

1,444NCT00428948

Tolvaptan Phase 3 Efficacy and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

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curl "https://conductscience.org/api/comparisons/v1?page=220"

Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=220

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT00336284-sae",
        "title": "Home Monitoring vs Conventional: serious adverse events",
        "summary": "124 of 977 against 74 of 473; risk difference -3.0 points, 95% interval -7.0 to 0.8; NCT00336284, TRUST: Lumos-T Safely RedUceS RouTine Office Device Follow-up",
        "record": "/library/comparisons/NCT00336284-sae",
        "nct_id": "NCT00336284",
        "kind": "serious-adverse-events",
        "participants": 1450,
        "risk_difference": {
          "value": -0.02952906273465175,
          "lower": -0.06998720274690237,
          "upper": 0.007842667473756178
        },
        "group_1": "124 of 977",
        "group_2": "74 of 473",
        "difference": "-3.0 points",
        "interval": "-7.0 to 0.8",
        "trial_title": "TRUST: Lumos-T Safely RedUceS RouTine Office Device Follow-up"
      },
      {
        "id": "NCT01382225-sae",
        "title": "Sodium Hyaluronate vs Vehicle: serious adverse events",
        "summary": "1 of 723 against 1 of 727; risk difference 0.0 points, 95% interval -0.6 to 0.7; NCT01382225, Sodium Hyaluronate Ophthalmic Solution, 0.18% for Treatment of Dry Eye Syndrome",
        "record": "/library/comparisons/NCT01382225-sae",
        "nct_id": "NCT01382225",
        "kind": "serious-adverse-events",
        "participants": 1450,
        "risk_difference": {
          "value": 0.000007610046021753374,
          "lower": -0.00646775365287758,
          "upper": 0.006516369677479039
        },
        "group_1": "1 of 723",
        "group_2": "1 of 727",
        "difference": "0.0 points",
        "interval": "-0.6 to 0.7",
        "trial_title": "Sodium Hyaluronate Ophthalmic Solution, 0.18% for Treatment of Dry Eye Syndrome"
      }
    ],
    "no_events": 33758,
    "columns": [
      {
        "key": "title",
        "label": "Comparison"
      },
      {
        "key": "group_1",
        "label": "With the outcome",
        "under": "group_2"
      },
      {
        "key": "difference",
        "label": "Risk difference, 95% interval",
        "under": "interval"
      },
      {
        "key": "participants",
        "label": "Participants"
      },
      {
        "key": "nct_id",
        "label": "Trial",
        "under": "trial_title"
      }
    ],
    "order": "Most participants first",
    "kinds": {
      "all": 85013,
      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
    }
  },
  "release": "trial-comparisons-2026-03-23-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "No license stated"
    }
  ],
  "next": "/api/comparisons/v1?page=221",
  "request_id": "IseCeZiRRmT7eCL1"
}

Ask about these results. The first 10 go in the prompt.

About this data
Holds
85,013 comparisons
From ClinicalTrials.gov. Counted 10 Nov 2026.
Release
23 Mar 2026
trial-comparisons-2026-03-23-0.1.0
Checked
20 of 20 review comparisons traced to ClinicalTrials.gov, and all 510,078 numbers calculated again apart from the builder agree
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Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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