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One gene with its proteins, patents, drugs, trials, grants and papers.
85,013 comparisons from ClinicalTrials.gov.
Most participants first33,758 with no events in either group come last4,381 to 4,400 of 85,013
| Comparison | With the outcome | Risk difference, 95% interval | Participants | Trial |
|---|---|---|---|---|
| Home Monitoring vs Conventional: serious adverse events | 124 of 977 74 of 473 | -3.0 points -7.0 to 0.8 | 1,450 | NCT00336284 TRUST: Lumos-T Safely RedUceS RouTine Office Device Follow-up |
| Sodium Hyaluronate vs Vehicle: serious adverse events | 1 of 723 1 of 727 | 0.0 points -0.6 to 0.7 | 1,450 | NCT01382225 Sodium Hyaluronate Ophthalmic Solution, 0.18% for Treatment of Dry Eye Syndrome |
| Cohort 1 vs Cohort 2: Number of Participants With Tacrolimus-related Neurotoxicities | 10 of 819 1 of 631 | 1.1 points 0.1 to 2.1 | 1,450 | NCT03083769 Functional Genetic Variants Affecting Tacrolimus Trough Levels and Side Effects in Chinese Renal Transplantation. |
| Cohort 1 vs Cohort 2: Number of Participants With Acute Rejection | 256 of 819 37 of 631 | 25.4 points 21.7 to 29.0 | 1,450 | NCT03083769 Functional Genetic Variants Affecting Tacrolimus Trough Levels and Side Effects in Chinese Renal Transplantation. |
| Cohort 1 vs Cohort 2: Number of Participants With Tacrolimus-related Nephrotoxicities | 26 of 819 2 of 631 | 2.9 points 1.6 to 4.3 | 1,450 | NCT03083769 Functional Genetic Variants Affecting Tacrolimus Trough Levels and Side Effects in Chinese Renal Transplantation. |
| Cohort 1 vs Cohort 2: serious adverse events | 256 of 819 37 of 631 | 25.4 points 21.7 to 29.0 | 1,450 | NCT03083769 Functional Genetic Variants Affecting Tacrolimus Trough Levels and Side Effects in Chinese Renal Transplantation. |
| Telmisartan 40mg and Amlodipine 10mg vs Telmisartan 80mg and Amlodipine 10mg: serious adverse events | 4 of 838 13 of 611 | -1.7 points -3.2 to -0.5 | 1,449 | NCT00624052 26-week Open Study of telmisartan40mg+amlodipine10mg or telmisartan80mg+amlodipine10 mg in Hypertension |
| Placebo: IPs vs Baloxavir Marboxil: IPs: Number of IPs With Serious Adverse Events (SAEs) | 2 of 726 1 of 723 | 0.1 points -0.5 to 0.9 | 1,449 | NCT03969212 Study to Assess the Efficacy of Baloxavir Marboxil Versus Placebo to Reduce Onward Transmission of Influenza A or B in Households |
| Placebo: IPs vs Baloxavir Marboxil: IPs: Number of IPs With Adverse Events (AEs) | 51 of 726 33 of 723 | 2.5 points 0.0 to 4.9 | 1,449 | NCT03969212 Study to Assess the Efficacy of Baloxavir Marboxil Versus Placebo to Reduce Onward Transmission of Influenza A or B in Households |
| Placebo: IPs vs Baloxavir Marboxil: IPs: serious adverse events | 2 of 726 1 of 723 | 0.1 points -0.5 to 0.9 | 1,449 | NCT03969212 Study to Assess the Efficacy of Baloxavir Marboxil Versus Placebo to Reduce Onward Transmission of Influenza A or B in Households |
| Combination of ARB and ACEI vs Monotherapy ARB: A Composite Endpoint of Reduction in Estimated GFR of 30ml/Min/1.73m*m in Individuals w/a Baseline Estimated GFR >= 60 ml/Min/1.73m*m, Reduction in Estimated GFR >50% in Individuals w/ Baseline Estimated GFR <60ml/Min/1.73m*m; ESRD or Death | 132 of 724 152 of 724 | -2.8 points -6.8 to 1.3 | 1,448 | NCT00555217 VA NEPHRON-D: Diabetes iN Nephropathy Study |
| Combination of ARB and ACEI vs Monotherapy ARB: A Renal Composite Endpoint, Defined as; Reduction in Estimated GFR of >50% (for Individuals With Baseline GFR <60) or Reduction in GFR of >30 (for Individuals With Baseline GFR >= GFR 60) or ESRD. | 77 of 724 101 of 724 | -3.3 points -6.7 to 0.1 | 1,448 | NCT00555217 VA NEPHRON-D: Diabetes iN Nephropathy Study |
| Combination of ARB and ACEI vs Monotherapy ARB: serious adverse events | 416 of 724 380 of 724 | 5.0 points -0.2 to 10.1 | 1,448 | NCT00555217 VA NEPHRON-D: Diabetes iN Nephropathy Study |
| EP2006: Any CIN/FN-related Chemotherapy Disturbance vs EP2006: no CIN/FN-related Chemotherapy Disturbance: Number of Participants With All-cause Mortality by CIN/FN-related Chemotherapy Disturbance | 3 of 138 53 of 1,309 | -1.9 points -3.7 to 2.3 | 1,447 | NCT01459653 Multi-level Evaluation of Chemotherapy-induced Febrile Neutropenia Prophylaxis, Outcomes, and Determinants With Granulocyte-colony Stimulating Factor |
| EP2006: Primary Prophylaxis vs EP2006: Secondary Prophylaxis: Number of Participants With Any CIN/FN-related Chemotherapy Disturbance by Prophylaxis Type | 78 of 1,046 60 of 401 | -7.5 points -11.6 to -3.9 | 1,447 | NCT01459653 Multi-level Evaluation of Chemotherapy-induced Febrile Neutropenia Prophylaxis, Outcomes, and Determinants With Granulocyte-colony Stimulating Factor |
| EP2006: Any Grade 4 CIN/FN vs EP2006: No Grade 4 CIN/FN: Number of Participants With All-cause Mortality by Any/no Grade 4 CIN and/or FN | 10 of 221 46 of 1,226 | 0.8 points -1.6 to 4.5 | 1,447 | NCT01459653 Multi-level Evaluation of Chemotherapy-induced Febrile Neutropenia Prophylaxis, Outcomes, and Determinants With Granulocyte-colony Stimulating Factor |
| MEDI8897 50 mg vs Placebo: deaths from any cause | 2 of 968 3 of 479 | -0.4 points -1.6 to 0.3 | 1,447 | NCT02878330 A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended RSV LRTI in Healthy Preterm Infants. |
| MEDI8897 50 mg vs Placebo: serious adverse events | 108 of 968 81 of 479 | -5.8 points -9.8 to -2.0 | 1,447 | NCT02878330 A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended RSV LRTI in Healthy Preterm Infants. |
| Regional Anesthesia vs General Anesthesia: Death or Inability to Walk 10 Feet or Across a Room Without Human Assistance | 132 of 712 132 of 733 | 0.5 points -3.5 to 4.5 | 1,445 | NCT02507505 Regional Versus General Anesthesia for Promoting Independence After Hip Fracture |
| Tolvaptan vs Placebo: serious adverse events | 177 of 961 95 of 483 | -1.3 points -5.7 to 2.9 | 1,444 | NCT00428948 Tolvaptan Phase 3 Efficacy and Safety Study in Autosomal Dominant Polycystic Kidney Disease (ADPKD) |
Code
curl "https://conductscience.org/api/comparisons/v1?page=220"
Response
The first 2 of this page's 20 results. GET /api/comparisons/v1?page=220
{
"data": {
"total": 85013,
"results": [
{
"id": "NCT00336284-sae",
"title": "Home Monitoring vs Conventional: serious adverse events",
"summary": "124 of 977 against 74 of 473; risk difference -3.0 points, 95% interval -7.0 to 0.8; NCT00336284, TRUST: Lumos-T Safely RedUceS RouTine Office Device Follow-up",
"record": "/library/comparisons/NCT00336284-sae",
"nct_id": "NCT00336284",
"kind": "serious-adverse-events",
"participants": 1450,
"risk_difference": {
"value": -0.02952906273465175,
"lower": -0.06998720274690237,
"upper": 0.007842667473756178
},
"group_1": "124 of 977",
"group_2": "74 of 473",
"difference": "-3.0 points",
"interval": "-7.0 to 0.8",
"trial_title": "TRUST: Lumos-T Safely RedUceS RouTine Office Device Follow-up"
},
{
"id": "NCT01382225-sae",
"title": "Sodium Hyaluronate vs Vehicle: serious adverse events",
"summary": "1 of 723 against 1 of 727; risk difference 0.0 points, 95% interval -0.6 to 0.7; NCT01382225, Sodium Hyaluronate Ophthalmic Solution, 0.18% for Treatment of Dry Eye Syndrome",
"record": "/library/comparisons/NCT01382225-sae",
"nct_id": "NCT01382225",
"kind": "serious-adverse-events",
"participants": 1450,
"risk_difference": {
"value": 0.000007610046021753374,
"lower": -0.00646775365287758,
"upper": 0.006516369677479039
},
"group_1": "1 of 723",
"group_2": "1 of 727",
"difference": "0.0 points",
"interval": "-0.6 to 0.7",
"trial_title": "Sodium Hyaluronate Ophthalmic Solution, 0.18% for Treatment of Dry Eye Syndrome"
}
],
"no_events": 33758,
"columns": [
{
"key": "title",
"label": "Comparison"
},
{
"key": "group_1",
"label": "With the outcome",
"under": "group_2"
},
{
"key": "difference",
"label": "Risk difference, 95% interval",
"under": "interval"
},
{
"key": "participants",
"label": "Participants"
},
{
"key": "nct_id",
"label": "Trial",
"under": "trial_title"
}
],
"order": "Most participants first",
"kinds": {
"all": 85013,
"outcome": 33568,
"serious-adverse-events": 31897,
"deaths": 19548
}
},
"release": "trial-comparisons-2026-03-23-0.1.0",
"terms": [
{
"source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
"license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "Freely available. Acknowledgement requested"
},
{
"source": "ClinicalTrials.gov",
"license": "none stated",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "No license stated"
}
],
"next": "/api/comparisons/v1?page=221",
"request_id": "IseCeZiRRmT7eCL1"
}Ask about these results. The first 10 go in the prompt.
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
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GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome
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