ConductScience.org, home

85,013 comparisons from ClinicalTrials.gov. Counted 2026-11-10.

85,013 comparisons

Most participants first33,758 with no events in either group come last1,101 to 1,120 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
Prioritized Clinical Decision Support vs Usual Care: serious adverse events722 of 4,550

763 of 4,387

-1.5 points

-3.1 to 0.0

8,937NCT02451670

Reducing Cardiovascular Risk in Adults With Serious Mental Illness

NB32 vs Placebo: Percentage of Participants With a Confirmed Occurrence of Myocardial Infarction (Nonfatal or Fatal)55 of 4,455

57 of 4,450

-0.0 points

-0.5 to 0.4

8,905NCT01601704

Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)

NB32 vs Placebo: Percentage of Participants With a Confirmed Occurrence of Cardiovascular Death (Including Fatal Myocardial Infarction, Fatal Stroke)17 of 4,455

34 of 4,450

-0.4 points

-0.7 to -0.1

8,905NCT01601704

Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)

NB32 vs Placebo: Percentage of Participants With a Confirmed Occurrence of Major Adverse Cardiovascular Event (MACE)90 of 4,455

102 of 4,450

-0.3 points

-0.9 to 0.3

8,905NCT01601704

Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)

NB32 vs Placebo: Percentage of Participants With a Confirmed Occurrence of Stroke (Nonfatal or Fatal)22 of 4,455

21 of 4,450

0.0 points

-0.3 to 0.3

8,905NCT01601704

Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)

NB32 vs Placebo: Percentage of Participants With a Confirmed Occurrence of Cardiovascular Death, Nonfatal Myocardial Infarction, Nonfatal Stroke, or Nonfatal Unstable Angina Requiring Hospitalization133 of 4,455

142 of 4,450

-0.2 points

-0.9 to 0.5

8,905NCT01601704

Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)

NB32 vs Placebo: serious adverse events463 of 4,455

386 of 4,450

1.7 points

0.5 to 2.9

8,905NCT01601704

Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)

LABA-LAMA-ICS vs LABA-LAMA: Number of Participants Hospitalised With Severe Exacerbation3,074 of 6,921

630 of 1,932

11.8 points

9.4 to 14.2

8,853NCT03724877

Effectiveness of Triple Therapy in COPD

LABA-LAMA-ICS vs LABA-LAMA: Number of Participants Hospitalised With Community-acquired Pneumonia (Serious Pneumonia)3,099 of 6,921

634 of 1,932

12.0 points

9.5 to 14.3

8,853NCT03724877

Effectiveness of Triple Therapy in COPD

LABA-LAMA-ICS vs LABA-LAMA: Number of Participants Hospitalised With Moderate Exacerbation2,487 of 6,921

542 of 1,932

7.9 points

5.5 to 10.1

8,853NCT03724877

Effectiveness of Triple Therapy in COPD

Brief Clinician Education vs Clinical Decision Support Nudges and Brief Clinician Education: Urine Testing for Non-specific Reasons1,127 of 4,535

1,032 of 4,264

0.6 points

-1.2 to 2.4

8,799NCT04289753

Behavioral Economics Applications to Geriatrics Leveraging EHRs R33 Trial

Cangrelor Arm vs Clopidogrel Arm: Incidence of Thrombolysis in Myocardial Infarction (TIMI) Major Bleeding19 of 4,374

14 of 4,365

0.1 points

-0.2 to 0.4

8,739NCT00305162

A Clinical Trial to Demonstrate the Efficacy of Cangrelor

Cangrelor Arm vs Clopidogrel Arm: Incidence of GUSTO Severe / Life-threatening Bleeding10 of 4,374

11 of 4,365

-0.0 points

-0.2 to 0.2

8,739NCT00305162

A Clinical Trial to Demonstrate the Efficacy of Cangrelor

Cangrelor Arm vs Clopidogrel Arm: Incidence of ACUITY Major Bleeding151 of 4,374

120 of 4,365

0.7 points

-0.0 to 1.4

8,739NCT00305162

A Clinical Trial to Demonstrate the Efficacy of Cangrelor

Cangrelor Arm vs Clopidogrel Arm: Incidence of ACUITY Major Bleeding (Without Hematoma >/= 5 cm)78 of 4,374

65 of 4,365

0.3 points

-0.2 to 0.8

8,739NCT00305162

A Clinical Trial to Demonstrate the Efficacy of Cangrelor

Cangrelor Arm vs Clopidogrel Arm: serious adverse events125 of 4,374

127 of 4,365

-0.1 points

-0.8 to 0.7

8,739NCT00305162

A Clinical Trial to Demonstrate the Efficacy of Cangrelor

E-ZES vs C-SES: To Compare Overall Definite or Probable Stent Thrombosis Rate of the Endeavor® Zotarolimus Eluting Coronary Stent System Versus the Cypher® Sirolimus-eluting Coronary Stent in a Patient Population Requiring Stent Implantation61 of 4,357

75 of 4,352

-0.3 points

-0.9 to 0.2

8,709NCT00476957

Randomized Study Comparing Endeavor With Cypher Stents (PROTECT)

E-ZES vs C-SES: serious adverse events579 of 4,357

507 of 4,352

1.6 points

0.3 to 3.0

8,709NCT00476957

Randomized Study Comparing Endeavor With Cypher Stents (PROTECT)

Rotarix Group vs Placebo Group: serious adverse events10 of 4,359

11 of 4,328

-0.0 points

-0.3 to 0.2

8,687NCT00329745

Year 3 Extension for Efficacy Follow-up in Subjects Vaccinated in Studies Rota-028, 029 or 030 (NCT00197210)

Flublok Quadrivalent Influenza Vaccine vs Inactivated Influenza Vaccine: Number of Participants With Unsolicited Adverse Events1,345 of 4,328

1,355 of 4,344

-0.1 points

-2.1 to 1.8

8,672NCT02285998

Protective Efficacy of Flublok® Quadrivalent Versus Licensed Inactivated Influenza Vaccine in Adults ≥50 Years of Age

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

No key needed

Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=56

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT02451670-sae",
        "title": "Prioritized Clinical Decision Support vs Usual Care: serious adverse events",
        "summary": "722 of 4550 against 763 of 4387; risk difference -1.5 points, 95% interval -3.1 to 0.0; NCT02451670, Reducing Cardiovascular Risk in Adults With Serious Mental Illness",
        "record": "/library/comparisons/NCT02451670-sae",
        "nct_id": "NCT02451670",
        "kind": "serious-adverse-events",
        "participants": 8937,
        "risk_difference": {
          "value": -0.015241635501494183,
          "lower": -0.030698952429049672,
          "upper": 0.000197191903036905
        },
        "group_1": "722 of 4,550",
        "group_2": "763 of 4,387",
        "difference": "-1.5 points",
        "interval": "-3.1 to 0.0",
        "trial_title": "Reducing Cardiovascular Risk in Adults With Serious Mental Illness"
      },
      {
        "id": "NCT01601704-3292f305",
        "title": "NB32 vs Placebo: Percentage of Participants With a Confirmed Occurrence of Myocardial Infarction (Nonfatal or Fatal)",
        "summary": "55 of 4455 against 57 of 4450; risk difference -0.0 points, 95% interval -0.5 to 0.4; NCT01601704, Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)",
        "record": "/library/comparisons/NCT01601704-3292f305",
        "nct_id": "NCT01601704",
        "kind": "outcome",
        "participants": 8905,
        "risk_difference": {
          "value": -0.0004633097516992656,
          "lower": -0.005171709080444309,
          "upper": 0.004234116650856166
        },
        "group_1": "55 of 4,455",
        "group_2": "57 of 4,450",
        "difference": "-0.0 points",
        "interval": "-0.5 to 0.4",
        "trial_title": "Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)"
      }
    ],
    "no_events": 33758,
    "columns": [
      {
        "key": "title",
        "label": "Comparison"
      },
      {
        "key": "group_1",
        "label": "With the outcome",
        "under": "group_2"
      },
      {
        "key": "difference",
        "label": "Risk difference, 95% interval",
        "under": "interval"
      },
      {
        "key": "participants",
        "label": "Participants"
      },
      {
        "key": "nct_id",
        "label": "Trial",
        "under": "trial_title"
      }
    ],
    "order": "Most participants first",
    "kinds": {
      "all": 85013,
      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
    }
  },
  "release": "trial-comparisons-2026-03-23-0.1.0",
  "terms": [
    {
      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "Freely available. Acknowledgement requested"
    },
    {
      "source": "ClinicalTrials.gov",
      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "None stated"
    }
  ],
  "next": "/api/comparisons/v1?page=57",
  "request_id": "ORnCs0idxII2eS2-"
}
trial-comparisons-2026-03-23-0.1.0Next page

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

Genes

NCBI Gene

One gene with its proteins, patents, drugs, trials, grants and papers.

Open193,990 genes2026-11-11

Trials

ClinicalTrials.gov

Search clinical trials by condition, drug, outcome or NCT number, with the results each one posted.

Open611,552 trials2026-11-12

Sequences

Patent publications

Paste a sequence and see the patents that disclose it.

For invited accounts.

Opens sequences.conductscience.org

By invitation39,249,078 sequences2026-11-05

For software

Read Trial comparisons from software.

Every answer on this page is also JSON, under /api/comparisons/v1. No key.

GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome

Ask an assistant

  • In FOURIER, how did serious adverse events compare between evolocumab and placebo?
  • Which metformin trials reported deaths, and what was the risk difference?
  • What was the number needed to treat for HELIOS-B's composite outcome?
  • Which placebo-controlled heart failure trials had the most participants?