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85,013 comparisons from ClinicalTrials.gov. Counted 2026-11-10.

85,013 comparisons

Most participants first33,758 with no events in either group come last1,261 to 1,280 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
Denosumab 60 mg Q6M vs Placebo: Number of Participants With New Vertebral Fractures86 of 3,702

264 of 3,691

-4.8 points

-5.8 to -3.9

7,393NCT00089791

A Study to Evaluate Denosumab in the Treatment of Postmenopausal Osteoporosis

Tiotropium vs Salmeterol: serious adverse events545 of 3,707

606 of 3,669

-1.8 points

-3.5 to -0.2

7,376NCT00563381

Tiotropium Once Daily 18 Mcg Versus Salmeterol Twice Daily 50 Mcg on Time to First Exacerbation in COPD Patients.

Finerenone vs Placebo: The First Occurrence of the Composite Endpoint of Onset of Kidney Failure, a Sustained Decrease of eGFR ≥40% From Baseline Over at Least 4 Weeks, or Renal Death.350 of 3,686

395 of 3,666

-1.3 points

-2.7 to 0.1

7,352NCT02545049

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease

Finerenone vs Placebo: All-cause Hospitalization1,573 of 3,686

1,605 of 3,666

-1.1 points

-3.4 to 1.2

7,352NCT02545049

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease

Finerenone vs Placebo: deaths from any cause339 of 3,686

383 of 3,666

-1.3 points

-2.6 to 0.1

7,352NCT02545049

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease

Finerenone vs Placebo: All-cause Mortality333 of 3,686

370 of 3,666

-1.1 points

-2.4 to 0.3

7,352NCT02545049

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease

Finerenone vs Placebo: The First Occurrence of the Composite Endpoint of Onset of Kidney Failure, a Sustained Decrease in eGFR of ≥57% From Baseline Over at Least 4 Weeks, or Renal Death108 of 3,686

139 of 3,666

-0.9 points

-1.7 to -0.0

7,352NCT02545049

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease

Finerenone vs Placebo: The First Occurrence of the Composite Endpoint of Cardiovascular Death, Non-fatal Myocardial Infarction, Non Fatal Stroke, or Hospitalization for Heart Failure.458 of 3,686

519 of 3,666

-1.7 points

-3.3 to -0.2

7,352NCT02545049

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease

Finerenone vs Placebo: serious adverse events1,158 of 3,683

1,215 of 3,658

-1.8 points

-3.9 to 0.4

7,341NCT02545049

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease

Apixaban 5 mg BID vs Placebo BID: serious adverse events894 of 3,672

884 of 3,643

0.1 points

-1.9 to 2.0

7,315NCT00831441

Phase III Acute Coronary Syndrome

Intensive Glycemic Control vs Standard Glycemic Control: Number of Participants With at Least One Non-vertebral Fracture198 of 3,655

189 of 3,632

0.2 points

-0.8 to 1.2

7,287NCT00324350

Intensive Glycemic Control and Skeletal Health Study

Comfort Talk® Training OSU vs Control OSU: No-shows in Q1FY16 (OSU)215 of 4,030

214 of 3,246

-1.3 points

-2.4 to -0.2

7,276NCT02427737

Comfort Talk and Economic Outcomes in MRI

Intervention Period vs Control Period: Viral Suppression2,880 of 3,165

3,849 of 4,085

-3.2 points

-4.5 to -2.0

7,250NCT02907944

Working With HIV Clinics to Adopt Addiction Treatments Using Implementation Facilitation

BIVA Studies vs Healthy Controls: deaths from any cause50 of 5,957

0 of 1,290

0.8 points

0.5 to 1.1

7,247NCT03502993

Personalised Risk Assessment in Febrile Illness to Optimise Real-life Management Across the European Union (PERFORM)

BIVA Studies vs Healthy Controls: serious adverse events120 of 5,957

0 of 1,290

2.0 points

1.6 to 2.4

7,247NCT03502993

Personalised Risk Assessment in Febrile Illness to Optimise Real-life Management Across the European Union (PERFORM)

VCIV vs Placebo: deaths from any cause2 of 3,623

0 of 3,620

0.1 points

-0.1 to 0.2

7,243NCT00800605

Immunogenicity Study of an Inactivated Influenza Vaccine (Split Virus, Vero Cell Derived) to Prevent Culture Confirmed Influenza Infection

VCIV vs Placebo: serious adverse events29 of 3,623

27 of 3,620

0.1 points

-0.4 to 0.5

7,243NCT00800605

Immunogenicity Study of an Inactivated Influenza Vaccine (Split Virus, Vero Cell Derived) to Prevent Culture Confirmed Influenza Infection

Derivation Cohort vs Validation Cohort: Very Late Stent Thrombosis92 of 5,185

35 of 2,058

0.1 points

-0.7 to 0.7

7,243NCT03491891

Factors Contribute to Very Late Stent Thrombosis After New Generation DES Implantation in China

BIVA Studies vs Controls for BIVA Studies: Number of Participants With Clinically-assigned Retrospective Phenotype655 of 5,952

0 of 1,290

11.0 points

10.2 to 11.8

7,242NCT03502993

Personalised Risk Assessment in Febrile Illness to Optimise Real-life Management Across the European Union (PERFORM)

Evaluation Period vs Control Period: Viral Suppression2,830 of 3,138

3,849 of 4,085

-4.0 points

-5.3 to -2.8

7,223NCT02907944

Working With HIV Clinics to Adopt Addiction Treatments Using Implementation Facilitation

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

No key needed

Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=64

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT00089791-cc35e52b",
        "title": "Denosumab 60 mg Q6M vs Placebo: Number of Participants With New Vertebral Fractures",
        "summary": "86 of 3702 against 264 of 3691; risk difference -4.8 points, 95% interval -5.8 to -3.9; NCT00089791, A Study to Evaluate Denosumab in the Treatment of Postmenopausal Osteoporosis",
        "record": "/library/comparisons/NCT00089791-cc35e52b",
        "nct_id": "NCT00089791",
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        "group_1": "86 of 3,702",
        "group_2": "264 of 3,691",
        "difference": "-4.8 points",
        "interval": "-5.8 to -3.9",
        "trial_title": "A Study to Evaluate Denosumab in the Treatment of Postmenopausal Osteoporosis"
      },
      {
        "id": "NCT00563381-sae",
        "title": "Tiotropium vs Salmeterol: serious adverse events",
        "summary": "545 of 3707 against 606 of 3669; risk difference -1.8 points, 95% interval -3.5 to -0.2; NCT00563381, Tiotropium Once Daily 18 Mcg Versus Salmeterol Twice Daily 50 Mcg on Time to First Exacerbation in COPD Patients.",
        "record": "/library/comparisons/NCT00563381-sae",
        "nct_id": "NCT00563381",
        "kind": "serious-adverse-events",
        "participants": 7376,
        "risk_difference": {
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        "group_1": "545 of 3,707",
        "group_2": "606 of 3,669",
        "difference": "-1.8 points",
        "interval": "-3.5 to -0.2",
        "trial_title": "Tiotropium Once Daily 18 Mcg Versus Salmeterol Twice Daily 50 Mcg on Time to First Exacerbation in COPD Patients."
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      "outcome": 33568,
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      "deaths": 19548
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  "terms": [
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      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
      "short": "Freely available. Acknowledgement requested"
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      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
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trial-comparisons-2026-03-23-0.1.0Next page

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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