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85,013 comparisons from ClinicalTrials.gov. Counted 2026-11-10.
Most participants first33,758 with no events in either group come last1,261 to 1,280 of 85,013
| Comparison | With the outcome | Risk difference, 95% interval | Participants | Trial |
|---|---|---|---|---|
| Denosumab 60 mg Q6M vs Placebo: Number of Participants With New Vertebral Fractures | 86 of 3,702 264 of 3,691 | -4.8 points -5.8 to -3.9 | 7,393 | NCT00089791 A Study to Evaluate Denosumab in the Treatment of Postmenopausal Osteoporosis |
| Tiotropium vs Salmeterol: serious adverse events | 545 of 3,707 606 of 3,669 | -1.8 points -3.5 to -0.2 | 7,376 | NCT00563381 Tiotropium Once Daily 18 Mcg Versus Salmeterol Twice Daily 50 Mcg on Time to First Exacerbation in COPD Patients. |
| Finerenone vs Placebo: The First Occurrence of the Composite Endpoint of Onset of Kidney Failure, a Sustained Decrease of eGFR ≥40% From Baseline Over at Least 4 Weeks, or Renal Death. | 350 of 3,686 395 of 3,666 | -1.3 points -2.7 to 0.1 | 7,352 | NCT02545049 Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease |
| Finerenone vs Placebo: All-cause Hospitalization | 1,573 of 3,686 1,605 of 3,666 | -1.1 points -3.4 to 1.2 | 7,352 | NCT02545049 Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease |
| Finerenone vs Placebo: deaths from any cause | 339 of 3,686 383 of 3,666 | -1.3 points -2.6 to 0.1 | 7,352 | NCT02545049 Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease |
| Finerenone vs Placebo: All-cause Mortality | 333 of 3,686 370 of 3,666 | -1.1 points -2.4 to 0.3 | 7,352 | NCT02545049 Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease |
| Finerenone vs Placebo: The First Occurrence of the Composite Endpoint of Onset of Kidney Failure, a Sustained Decrease in eGFR of ≥57% From Baseline Over at Least 4 Weeks, or Renal Death | 108 of 3,686 139 of 3,666 | -0.9 points -1.7 to -0.0 | 7,352 | NCT02545049 Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease |
| Finerenone vs Placebo: The First Occurrence of the Composite Endpoint of Cardiovascular Death, Non-fatal Myocardial Infarction, Non Fatal Stroke, or Hospitalization for Heart Failure. | 458 of 3,686 519 of 3,666 | -1.7 points -3.3 to -0.2 | 7,352 | NCT02545049 Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease |
| Finerenone vs Placebo: serious adverse events | 1,158 of 3,683 1,215 of 3,658 | -1.8 points -3.9 to 0.4 | 7,341 | NCT02545049 Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diabetic Kidney Disease |
| Apixaban 5 mg BID vs Placebo BID: serious adverse events | 894 of 3,672 884 of 3,643 | 0.1 points -1.9 to 2.0 | 7,315 | NCT00831441 Phase III Acute Coronary Syndrome |
| Intensive Glycemic Control vs Standard Glycemic Control: Number of Participants With at Least One Non-vertebral Fracture | 198 of 3,655 189 of 3,632 | 0.2 points -0.8 to 1.2 | 7,287 | NCT00324350 Intensive Glycemic Control and Skeletal Health Study |
| Comfort Talk® Training OSU vs Control OSU: No-shows in Q1FY16 (OSU) | 215 of 4,030 214 of 3,246 | -1.3 points -2.4 to -0.2 | 7,276 | NCT02427737 Comfort Talk and Economic Outcomes in MRI |
| Intervention Period vs Control Period: Viral Suppression | 2,880 of 3,165 3,849 of 4,085 | -3.2 points -4.5 to -2.0 | 7,250 | NCT02907944 Working With HIV Clinics to Adopt Addiction Treatments Using Implementation Facilitation |
| BIVA Studies vs Healthy Controls: deaths from any cause | 50 of 5,957 0 of 1,290 | 0.8 points 0.5 to 1.1 | 7,247 | NCT03502993 Personalised Risk Assessment in Febrile Illness to Optimise Real-life Management Across the European Union (PERFORM) |
| BIVA Studies vs Healthy Controls: serious adverse events | 120 of 5,957 0 of 1,290 | 2.0 points 1.6 to 2.4 | 7,247 | NCT03502993 Personalised Risk Assessment in Febrile Illness to Optimise Real-life Management Across the European Union (PERFORM) |
| VCIV vs Placebo: deaths from any cause | 2 of 3,623 0 of 3,620 | 0.1 points -0.1 to 0.2 | 7,243 | NCT00800605 Immunogenicity Study of an Inactivated Influenza Vaccine (Split Virus, Vero Cell Derived) to Prevent Culture Confirmed Influenza Infection |
| VCIV vs Placebo: serious adverse events | 29 of 3,623 27 of 3,620 | 0.1 points -0.4 to 0.5 | 7,243 | NCT00800605 Immunogenicity Study of an Inactivated Influenza Vaccine (Split Virus, Vero Cell Derived) to Prevent Culture Confirmed Influenza Infection |
| Derivation Cohort vs Validation Cohort: Very Late Stent Thrombosis | 92 of 5,185 35 of 2,058 | 0.1 points -0.7 to 0.7 | 7,243 | NCT03491891 Factors Contribute to Very Late Stent Thrombosis After New Generation DES Implantation in China |
| BIVA Studies vs Controls for BIVA Studies: Number of Participants With Clinically-assigned Retrospective Phenotype | 655 of 5,952 0 of 1,290 | 11.0 points 10.2 to 11.8 | 7,242 | NCT03502993 Personalised Risk Assessment in Febrile Illness to Optimise Real-life Management Across the European Union (PERFORM) |
| Evaluation Period vs Control Period: Viral Suppression | 2,830 of 3,138 3,849 of 4,085 | -4.0 points -5.3 to -2.8 | 7,223 | NCT02907944 Working With HIV Clinics to Adopt Addiction Treatments Using Implementation Facilitation |
Response
The first 2 of this page's 20 results. GET /api/comparisons/v1?page=64
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"title": "Denosumab 60 mg Q6M vs Placebo: Number of Participants With New Vertebral Fractures",
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"trial_title": "A Study to Evaluate Denosumab in the Treatment of Postmenopausal Osteoporosis"
},
{
"id": "NCT00563381-sae",
"title": "Tiotropium vs Salmeterol: serious adverse events",
"summary": "545 of 3707 against 606 of 3669; risk difference -1.8 points, 95% interval -3.5 to -0.2; NCT00563381, Tiotropium Once Daily 18 Mcg Versus Salmeterol Twice Daily 50 Mcg on Time to First Exacerbation in COPD Patients.",
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"terms": [
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}ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
NCBI Gene
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Every answer on this page is also JSON, under /api/comparisons/v1. No key.
GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome
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