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85,013 comparisons from ClinicalTrials.gov. Counted 2026-11-10.

85,013 comparisons

Most participants first33,758 with no events in either group come last1,681 to 1,700 of 85,013

Show the results as
ComparisonWith the outcomeRisk difference, 95% intervalParticipantsTrial
Opt-in vs Opt-out: serious adverse events1 of 3,909

4 of 1,267

-0.3 points

-0.8 to -0.1

5,176NCT04536038

Framing Clinical Trial Enrollment for Patients With Peripheral Artery Disease

AZD7442 vs Placebo: The Incidence of SARS-CoV-2 RT-PCR-positive Severe or Critical Symptomatic Illness Occurring After Dosing With IMP2 of 3,441

11 of 1,731

-0.6 points

-1.1 to -0.3

5,172NCT04625725

Phase III Double-blind, Placebo-controlled Study of AZD7442 for Pre-exposure Prophylaxis of COVID-19 in Adult.

AZD7442 vs Placebo: The Incidence of COVID-19-related Emergency Department Visits Occurring After Dosing With IMP8 of 3,441

8 of 1,731

-0.2 points

-0.7 to 0.1

5,172NCT04625725

Phase III Double-blind, Placebo-controlled Study of AZD7442 for Pre-exposure Prophylaxis of COVID-19 in Adult.

FluLaval® Quadrivalent Group vs Havrix Group: serious adverse events36 of 2,584

24 of 2,584

0.5 points

-0.1 to 1.1

5,168NCT01218308

A Study to Evaluate the Efficacy of GSK Biologicals' Influenza Vaccine in Children

Treatment - Participation in Nurse Family Partnership Nurse-Family Partnership vs Control: Number of Participants Experiencing Severe Acute Maternal Morbidity56 of 3,464

23 of 1,694

0.3 points

-0.5 to 0.9

5,158NCT03360539

Nurse-Family Partnership Impact Evaluation in South Carolina

Placebo (Core+SE I+SE II) vs Bazedoxifene 20 mg (SE II): Number of Participants With Worsening Vertebral Fractures Through Month 841 of 1,741

7 of 3,410

-0.1 points

-0.4 to 0.1

5,151NCT00205777

Study Evaluating Bazedoxifene Acetate In Osteoporosis In Postmenopausal Women

Lifestyle Intervention vs Diabetes Support and Education: First Occurrence of Major Clinical Events577 of 2,570

600 of 2,575

-0.8 points

-3.1 to 1.4

5,145NCT00017953

Look AHEAD: Action for Health in Diabetes

Lifestyle Intervention vs Diabetes Support and Education: First Occurrence of Death, Myocardial Infarction, or Hospitalized Angina496 of 2,570

529 of 2,575

-1.2 points

-3.4 to 0.9

5,145NCT00017953

Look AHEAD: Action for Health in Diabetes

Lifestyle Intervention vs Diabetes Support and Education: First Occurrence of a Severe Cardiovascular Event403 of 2,570

418 of 2,575

-0.6 points

-2.6 to 1.5

5,145NCT00017953

Look AHEAD: Action for Health in Diabetes

Lifestyle Intervention vs Diabetes Support and Education: deaths from any cause174 of 2,570

202 of 2,575

-1.1 points

-2.5 to 0.4

5,145NCT00017953

Look AHEAD: Action for Health in Diabetes

Lifestyle Intervention vs Diabetes Support and Education: First Occurrence of Cardiovascular Death, Myocardial Infarction, or Stroke267 of 2,570

283 of 2,575

-0.6 points

-2.3 to 1.1

5,145NCT00017953

Look AHEAD: Action for Health in Diabetes

Lifestyle Intervention vs Diabetes Support and Education: serious adverse events639 of 2,570

596 of 2,575

1.7 points

-0.6 to 4.1

5,145NCT00017953

Look AHEAD: Action for Health in Diabetes

RSV MAT Group - Infant vs Placebo Group - Infant: Number of Infant Participants With RSV-associated Hospitalizations From Birth to Day 181 Post-birth14 of 3,426

14 of 1,711

-0.4 points

-1.0 to 0.0

5,137NCT04605159

A Phase III, Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers

RSV MAT Group - Infant vs Placebo Group - Infant: Number of Infant Participants With All-cause LRTIs With Hospitalization From Birth to Day 181 Post-birth30 of 3,426

22 of 1,711

-0.4 points

-1.1 to 0.2

5,137NCT04605159

A Phase III, Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers

RSV MAT Group - Infant vs Placebo Group - Infant: Number of Infant Participants With Medically Assessed, RSV-associated LRTIs of Any Severity From Birth to Day 121 Post-birth9 of 3,426

15 of 1,711

-0.6 points

-1.2 to -0.2

5,137NCT04605159

A Phase III, Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers

RSV MAT Group - Infant vs Placebo Group - Infant: Number of Infant Participants With Medically Assessed, RSV-associated Severe LRTIs From Birth to Day 121 Post-birth6 of 3,426

9 of 1,711

-0.4 points

-0.8 to -0.0

5,137NCT04605159

A Phase III, Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers

RSV MAT Group - Infant vs Placebo Group - Infant: Number of Infant Participants With All-cause Pneumonia From Birth to Day 181 Post-birth36 of 3,426

17 of 1,711

0.1 points

-0.6 to 0.6

5,137NCT04605159

A Phase III, Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers

RSV MAT Group - Infant vs Placebo Group - Infant: Number of Infant Participants With All-cause LRTIs From Birth to Day 181 Post-birth162 of 3,426

103 of 1,711

-1.3 points

-2.7 to -0.0

5,137NCT04605159

A Phase III, Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers

RSV MAT Group - Infant vs Placebo Group - Infant: Number of Infant Participants With Medically Assessed, RSV-associated Severe LRTIs From Birth to Day 366 Post-birth38 of 3,426

22 of 1,711

-0.2 points

-0.9 to 0.4

5,137NCT04605159

A Phase III, Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers

RSV MAT Group - Infant vs Placebo Group - Infant: Number of Infant Participants With Medically Assessed, RSV-associated LRTIs of Any Severity From Birth to Day 366 Post-birth67 of 3,426

43 of 1,711

-0.6 points

-1.5 to 0.3

5,137NCT04605159

A Phase III, Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers

Request

GET /api/comparisons/v1

Words from a trial's title, conditions or interventions, its outcome or its groups, or an NCT number.

An outcome counted in participants, the serious adverse events, or the deaths from any cause.

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Response

The first 2 of this page's 20 results. GET /api/comparisons/v1?page=85

{
  "data": {
    "total": 85013,
    "results": [
      {
        "id": "NCT04536038-sae",
        "title": "Opt-in vs Opt-out: serious adverse events",
        "summary": "1 of 3909 against 4 of 1267; risk difference -0.3 points, 95% interval -0.8 to -0.1; NCT04536038, Framing Clinical Trial Enrollment for Patients With Peripheral Artery Disease",
        "record": "/library/comparisons/NCT04536038-sae",
        "nct_id": "NCT04536038",
        "kind": "serious-adverse-events",
        "participants": 5176,
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        },
        "group_1": "1 of 3,909",
        "group_2": "4 of 1,267",
        "difference": "-0.3 points",
        "interval": "-0.8 to -0.1",
        "trial_title": "Framing Clinical Trial Enrollment for Patients With Peripheral Artery Disease"
      },
      {
        "id": "NCT04625725-1e59c014",
        "title": "AZD7442 vs Placebo: The Incidence of SARS-CoV-2 RT-PCR-positive Severe or Critical Symptomatic Illness Occurring After Dosing With IMP",
        "summary": "2 of 3441 against 11 of 1731; risk difference -0.6 points, 95% interval -1.1 to -0.3; NCT04625725, Phase III Double-blind, Placebo-controlled Study of AZD7442 for Pre-exposure Prophylaxis of COVID-19 in Adult.",
        "record": "/library/comparisons/NCT04625725-1e59c014",
        "nct_id": "NCT04625725",
        "kind": "outcome",
        "participants": 5172,
        "risk_difference": {
          "value": -0.005773481873442739,
          "lower": -0.010780081266573573,
          "upper": -0.0025776978183783086
        },
        "group_1": "2 of 3,441",
        "group_2": "11 of 1,731",
        "difference": "-0.6 points",
        "interval": "-1.1 to -0.3",
        "trial_title": "Phase III Double-blind, Placebo-controlled Study of AZD7442 for Pre-exposure Prophylaxis of COVID-19 in Adult."
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    "no_events": 33758,
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      "all": 85013,
      "outcome": 33568,
      "serious-adverse-events": 31897,
      "deaths": 19548
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      "source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
      "license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
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      "license": "none stated",
      "notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
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trial-comparisons-2026-03-23-0.1.0Next page

Sources 2

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.

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