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85,013 comparisons from ClinicalTrials.gov. Counted 2026-11-10.
Most participants first33,758 with no events in either group come last1,681 to 1,700 of 85,013
| Comparison | With the outcome | Risk difference, 95% interval | Participants | Trial |
|---|---|---|---|---|
| Opt-in vs Opt-out: serious adverse events | 1 of 3,909 4 of 1,267 | -0.3 points -0.8 to -0.1 | 5,176 | NCT04536038 Framing Clinical Trial Enrollment for Patients With Peripheral Artery Disease |
| AZD7442 vs Placebo: The Incidence of SARS-CoV-2 RT-PCR-positive Severe or Critical Symptomatic Illness Occurring After Dosing With IMP | 2 of 3,441 11 of 1,731 | -0.6 points -1.1 to -0.3 | 5,172 | NCT04625725 Phase III Double-blind, Placebo-controlled Study of AZD7442 for Pre-exposure Prophylaxis of COVID-19 in Adult. |
| AZD7442 vs Placebo: The Incidence of COVID-19-related Emergency Department Visits Occurring After Dosing With IMP | 8 of 3,441 8 of 1,731 | -0.2 points -0.7 to 0.1 | 5,172 | NCT04625725 Phase III Double-blind, Placebo-controlled Study of AZD7442 for Pre-exposure Prophylaxis of COVID-19 in Adult. |
| FluLaval® Quadrivalent Group vs Havrix Group: serious adverse events | 36 of 2,584 24 of 2,584 | 0.5 points -0.1 to 1.1 | 5,168 | NCT01218308 A Study to Evaluate the Efficacy of GSK Biologicals' Influenza Vaccine in Children |
| Treatment - Participation in Nurse Family Partnership Nurse-Family Partnership vs Control: Number of Participants Experiencing Severe Acute Maternal Morbidity | 56 of 3,464 23 of 1,694 | 0.3 points -0.5 to 0.9 | 5,158 | NCT03360539 Nurse-Family Partnership Impact Evaluation in South Carolina |
| Placebo (Core+SE I+SE II) vs Bazedoxifene 20 mg (SE II): Number of Participants With Worsening Vertebral Fractures Through Month 84 | 1 of 1,741 7 of 3,410 | -0.1 points -0.4 to 0.1 | 5,151 | NCT00205777 Study Evaluating Bazedoxifene Acetate In Osteoporosis In Postmenopausal Women |
| Lifestyle Intervention vs Diabetes Support and Education: First Occurrence of Major Clinical Events | 577 of 2,570 600 of 2,575 | -0.8 points -3.1 to 1.4 | 5,145 | NCT00017953 Look AHEAD: Action for Health in Diabetes |
| Lifestyle Intervention vs Diabetes Support and Education: First Occurrence of Death, Myocardial Infarction, or Hospitalized Angina | 496 of 2,570 529 of 2,575 | -1.2 points -3.4 to 0.9 | 5,145 | NCT00017953 Look AHEAD: Action for Health in Diabetes |
| Lifestyle Intervention vs Diabetes Support and Education: First Occurrence of a Severe Cardiovascular Event | 403 of 2,570 418 of 2,575 | -0.6 points -2.6 to 1.5 | 5,145 | NCT00017953 Look AHEAD: Action for Health in Diabetes |
| Lifestyle Intervention vs Diabetes Support and Education: deaths from any cause | 174 of 2,570 202 of 2,575 | -1.1 points -2.5 to 0.4 | 5,145 | NCT00017953 Look AHEAD: Action for Health in Diabetes |
| Lifestyle Intervention vs Diabetes Support and Education: First Occurrence of Cardiovascular Death, Myocardial Infarction, or Stroke | 267 of 2,570 283 of 2,575 | -0.6 points -2.3 to 1.1 | 5,145 | NCT00017953 Look AHEAD: Action for Health in Diabetes |
| Lifestyle Intervention vs Diabetes Support and Education: serious adverse events | 639 of 2,570 596 of 2,575 | 1.7 points -0.6 to 4.1 | 5,145 | NCT00017953 Look AHEAD: Action for Health in Diabetes |
| RSV MAT Group - Infant vs Placebo Group - Infant: Number of Infant Participants With RSV-associated Hospitalizations From Birth to Day 181 Post-birth | 14 of 3,426 14 of 1,711 | -0.4 points -1.0 to 0.0 | 5,137 | NCT04605159 A Phase III, Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers |
| RSV MAT Group - Infant vs Placebo Group - Infant: Number of Infant Participants With All-cause LRTIs With Hospitalization From Birth to Day 181 Post-birth | 30 of 3,426 22 of 1,711 | -0.4 points -1.1 to 0.2 | 5,137 | NCT04605159 A Phase III, Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers |
| RSV MAT Group - Infant vs Placebo Group - Infant: Number of Infant Participants With Medically Assessed, RSV-associated LRTIs of Any Severity From Birth to Day 121 Post-birth | 9 of 3,426 15 of 1,711 | -0.6 points -1.2 to -0.2 | 5,137 | NCT04605159 A Phase III, Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers |
| RSV MAT Group - Infant vs Placebo Group - Infant: Number of Infant Participants With Medically Assessed, RSV-associated Severe LRTIs From Birth to Day 121 Post-birth | 6 of 3,426 9 of 1,711 | -0.4 points -0.8 to -0.0 | 5,137 | NCT04605159 A Phase III, Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers |
| RSV MAT Group - Infant vs Placebo Group - Infant: Number of Infant Participants With All-cause Pneumonia From Birth to Day 181 Post-birth | 36 of 3,426 17 of 1,711 | 0.1 points -0.6 to 0.6 | 5,137 | NCT04605159 A Phase III, Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers |
| RSV MAT Group - Infant vs Placebo Group - Infant: Number of Infant Participants With All-cause LRTIs From Birth to Day 181 Post-birth | 162 of 3,426 103 of 1,711 | -1.3 points -2.7 to -0.0 | 5,137 | NCT04605159 A Phase III, Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers |
| RSV MAT Group - Infant vs Placebo Group - Infant: Number of Infant Participants With Medically Assessed, RSV-associated Severe LRTIs From Birth to Day 366 Post-birth | 38 of 3,426 22 of 1,711 | -0.2 points -0.9 to 0.4 | 5,137 | NCT04605159 A Phase III, Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers |
| RSV MAT Group - Infant vs Placebo Group - Infant: Number of Infant Participants With Medically Assessed, RSV-associated LRTIs of Any Severity From Birth to Day 366 Post-birth | 67 of 3,426 43 of 1,711 | -0.6 points -1.5 to 0.3 | 5,137 | NCT04605159 A Phase III, Double-blind Study to Assess Safety and Efficacy of an RSV Maternal Unadjuvanted Vaccine, in Pregnant Women and Infants Born to Vaccinated Mothers |
Response
The first 2 of this page's 20 results. GET /api/comparisons/v1?page=85
{
"data": {
"total": 85013,
"results": [
{
"id": "NCT04536038-sae",
"title": "Opt-in vs Opt-out: serious adverse events",
"summary": "1 of 3909 against 4 of 1267; risk difference -0.3 points, 95% interval -0.8 to -0.1; NCT04536038, Framing Clinical Trial Enrollment for Patients With Peripheral Artery Disease",
"record": "/library/comparisons/NCT04536038-sae",
"nct_id": "NCT04536038",
"kind": "serious-adverse-events",
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"risk_difference": {
"value": -0.0029012440277561566,
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},
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"group_2": "4 of 1,267",
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"trial_title": "Framing Clinical Trial Enrollment for Patients With Peripheral Artery Disease"
},
{
"id": "NCT04625725-1e59c014",
"title": "AZD7442 vs Placebo: The Incidence of SARS-CoV-2 RT-PCR-positive Severe or Critical Symptomatic Illness Occurring After Dosing With IMP",
"summary": "2 of 3441 against 11 of 1731; risk difference -0.6 points, 95% interval -1.1 to -0.3; NCT04625725, Phase III Double-blind, Placebo-controlled Study of AZD7442 for Pre-exposure Prophylaxis of COVID-19 in Adult.",
"record": "/library/comparisons/NCT04625725-1e59c014",
"nct_id": "NCT04625725",
"kind": "outcome",
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},
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"difference": "-0.6 points",
"interval": "-1.1 to -0.3",
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}
],
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"columns": [
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"release": "trial-comparisons-2026-03-23-0.1.0",
"terms": [
{
"source": "ClinicalTrials.gov's posted results, through CTTI's AACT",
"license": "ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
"short": "Freely available. Acknowledgement requested"
},
{
"source": "ClinicalTrials.gov",
"license": "none stated",
"notice": "ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.",
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"next": "/api/comparisons/v1?page=86",
"request_id": "i0fb6f8OZ9zPxM-E"
}ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions. The measures are ConductScience's calculation from them.
NCBI Gene
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Every answer on this page is also JSON, under /api/comparisons/v1. No key.
GET https://conductscience.org/api/comparisons/v1?q=placebo%20heart%20failure&kind=outcome
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