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Disease · EFO_0007248

egg allergy

6 sourcesdiseases-2026-09-18-0.1.0

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ConductScience Library. egg allergy. Diseases, record EFO_0007248. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/EFO_0007248

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Disease

Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.

Name
egg allergy
Open Targets
Open Targets ID
EFO_0007248
Open Targets
Other names
Allergy to eggs (disorder), Egg Hypersensitivity
Open Targets
Disease Ontology
DOID:4377
Disease Ontology
MeSH
D021181
MeSH
Highest stage of its drugs
Phase 3, for 1 of its 4 drugs, from ClinicalTrials.gov
Open Targets

Drugs4

The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DrugChEMBL IDTypeOpen Targets' stageStage reported byReportsOf them trialsTrials shown hereSource
OMALIZUMABCHEMBL1201589AntibodyPhase 3ClinicalTrials.gov333Drugs and targets
INFLUENZA A VIRUS, SPLIT VIRIONCHEMBL6068363Vaccine componentUnknownClinicalTrials.gov110Drugs and targets
INFLUENZA VIRUS VACCINECHEMBL2109042Vaccine componentUnknownClinicalTrials.gov110Drugs and targets
SODIUM CHLORIDECHEMBL1200574Small moleculeUnknownClinicalTrials.gov111Drugs and targets

Targets1

The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.

TargetProteinIts drugs that act on itMechanismsHighest stage of those drugsGene in Genes
IGHEImmunoglobulin heavy constant epsilon1Ig epsilon chain C region inhibitorPhase 3https://conductscience.org/library/genes/3497

Trials4

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT03881696Omalizumab as Monotherapy and as Adjunct Therapy to Multi-Allergen OIT in Food Allergic ParticipantsPhase 34582024-06-04Peanut Allergy, Multi-food AllergyOMALIZUMABIts record names the diseaseClinicalTrials.gov
NCT03181009Multi OIT to Test Immune Markers After Minimum Maintenance DosePhase 2602019-09-20Food AllergyOMALIZUMABIts record names the diseaseClinicalTrials.gov
NCT01264601Safe Administration of Flu Vaccine to Egg Allergic ChildrenNot applicable312017-10-26Egg AllergySODIUM CHLORIDEIts record names the diseaseClinicalTrials.gov
NCT06103656E-B-FAHF-2, Multi OIT and Xolair for Food AllergyPhase 233Food AllergyOMALIZUMABOpen Targets' reading of its recordClinicalTrials.gov

Comparisons in its trials5

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Omalizumab vs Placebo for Omalizumab: deaths from any cause0 of 1200 of 60180NCT03881696Trial comparisons
Omalizumab vs Placebo for Omalizumab: serious adverse events4 of 1201 of 60180NCT03881696Trial comparisons
Group A (300 mg Maintenance Dose) vs Group B (1200 Maintenance Dose): deaths from any cause0 of 300 of 3060NCT03181009Trial comparisons
Group A (300 mg Maintenance Dose) vs Group B (1200 Maintenance Dose): serious adverse events0 of 300 of 3060NCT03181009Trial comparisons
Single Dose vs Graded Challenge: serious adverse events0 of 170 of 1431NCT01264601Trial comparisons

Papers from its trials4

The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
38407394RESULT1PubMed
37087097RESULT1PubMed
35014049RESULT1PubMed
41651410DERIVED1PubMed

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
Drug links and their checks, from Drugs and targets
2026-09-18
Drugs and targets
ClinicalTrials.gov, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
PubMed, for the checks
2026-11-06
PubMed
MeSH, for the checks
2026-11-10
MeSH

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this disease from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/diseases/v1/EFO_0007248

GET https://conductscience.org/api/diseases/v1/EFO_0007248/drugs