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Disease · MONDO_0001039

tonsillitis

6 sourcesdiseases-2026-09-18-0.1.0

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ConductScience Library. tonsillitis. Diseases, record MONDO_0001039. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/MONDO_0001039

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Disease

Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.

Name
tonsillitis
Open Targets
Open Targets ID
MONDO_0001039
Open Targets
Other names
chronic tonsillitis, inflammation of tonsil, tonsil inflammation, tonsilitis
Open Targets
Disease Ontology
DOID:10456
Disease Ontology
MeSH
D014069
MeSH
NCI Thesaurus
C116006
NCI Thesaurus
Highest stage of its drugs
Approval, for 4 of its 12 drugs, from PMDA
Open Targets

Drugs12

The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DrugChEMBL IDTypeOpen Targets' stageStage reported byReportsOf them trialsTrials shown hereSource
TELITHROMYCINCHEMBL1136Small moleculeApprovalEMA Human Drugs, at withdrawal311Drugs and targets
GARENOXACIN MESYLATECHEMBL3183451Small moleculeApprovalPMDA100Drugs and targets
LASCUFLOXACINCHEMBL6068006Small moleculeApprovalPMDA100Drugs and targets
SITAFLOXACINCHEMBL3989504Small moleculeApprovalPMDA100Drugs and targets
AZITHROMYCINCHEMBL529Small moleculePhase 3ClinicalTrials.gov222Drugs and targets
CLARITHROMYCINCHEMBL1741Small moleculePhase 3ClinicalTrials.gov111Drugs and targets
MIKAMYCINCHEMBL5314344Phase 3ClinicalTrials.gov110Drugs and targets
PENICILLIN VCHEMBL615Small moleculePhase 3ClinicalTrials.gov111Drugs and targets
AMOXICILLINCHEMBL1082Small moleculeUnknownClinicalTrials.gov111Drugs and targets
CLAVULANIC ACIDCHEMBL777Small moleculeUnknownClinicalTrials.gov111Drugs and targets

1 to 10 of 12

See all 12 drugs

Targets0

The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.

None in this release.

Trials7

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 1 more is not shown, since the checks do not confirm it.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT01919996PASS Study To Evaluate The Potential Of Zithromax To Cause Ocular Problems In Pediatric PatientsPhase 282016-07-06Pharyngitis, TonsillitisAZITHROMYCINIts record names the diseaseClinicalTrials.gov
NCT01690533Special Drug Use Investigation - Assessment of Efficacy and Safety in Treating Secondary Infection of Chronic Respiratory Disease497Anti-Infective AgentsMOXIFLOXACINIts record names the diseaseClinicalTrials.gov
NCT01406275Special Drug Use Investigation for CLAVAMOX® (Amoxicillin/Clavulanate) Pediatrics Dry Syrup (Every Indication Excluded Otitis Media)363Otitis MaediaAMOXICILLIN, CLAVULANIC ACIDIts record names the diseaseClinicalTrials.gov
NCT04215770Comparison of Intravenous Co-amoxiclav Versus Benzyl PenicillinNot applicable310Tonsillitis StreptococcalPENICILLIN GIts record names the diseaseClinicalTrials.gov
NCT04016051Acceptance of Clarithromycin in a Straw Compared to Syrup in Children With Upper Respiratory Tract InfectionsPhase 3265Otitis Media, Tonsillitis, Pharyngitis, BronchitisCLARITHROMYCINIts record names the diseaseClinicalTrials.gov
NCT00315549TELI TAD - Telithromycin in Tonsillitis in Adolescents and AdultsPhase 3233Tonsillitis, PharyngitisPENICILLIN V, TELITHROMYCINIts record names the diseaseClinicalTrials.gov
NCT00393835A Trial Of Azithromycin SR For The Treatment Of Laryngopharyngitis or Tonsillitis or Acute Bacterial RhinosinusitisPhase 399Upper Respiratory Tract InfectionAZITHROMYCINIts record names the diseaseClinicalTrials.gov

Comparisons in its trials0

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

None in this release.

Papers from its trials0

The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

None in this release.

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
Drug links and their checks, from Drugs and targets
2026-09-18
Drugs and targets
ClinicalTrials.gov, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
PubMed, for the checks
2026-11-06
PubMed
MeSH, for the checks
2026-11-10
MeSH

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this disease from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0001039

GET https://conductscience.org/api/diseases/v1/MONDO_0001039/drugs