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Disease · MONDO_0001134

Comparisons in its trials29

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Valsartan/Amlodipine 160/5 mg vs Amlodipine 10 mg: serious adverse events11 of 5928 of 5911,183NCT00437645Trial comparisons
Azilsartan Medoxomil and Chlorthalidone vs Olmesartan Medoxomil and Hydrochlorothiazide: serious adverse events24 of 41826 of 419837NCT00996281Trial comparisons
Losartan 50 mg/HCTZ 12.5 mg vs Valsartan 80 mg/HCTZ 12.5 mg: serious adverse events11 of 4255 of 383808NCT00546754Trial comparisons
T80/A5 vs T80/A10: serious adverse events1 of 5011 of 232733NCT01134393Trial comparisons
Azilsartan vs Amlodipine: serious adverse events0 of 3595 of 359718NCT01762501Trial comparisons
Cohort 1 vs Cohort 2: serious adverse events30 of 36222 of 307669NCT00695955Trial comparisons
Eprosartan vs Eprosartan Mesylate: serious adverse events3 of 3327 of 332664NCT01631227Trial comparisons
Valsartan/Amlodipine 160/5 mg vs Valsartan 160 mg: serious adverse events0 of 3291 of 325654NCT01001572Trial comparisons
Azilsartan Medoxomil 40 mg/Chlorthalidone 12.5 mg QD vs Azilsartan Medoxomil 40 mg + Hydrochlorothiazide 12.5 mg QD: serious adverse events6 of 3025 of 303605NCT00818883Trial comparisons
Telmisartan 40 mg Plus Amlodipine 5 mg Fixed-dose Combination vs Amlodipine 5 mg Monotherapy: serious adverse events1 of 2692 of 262531NCT00558064Trial comparisons
Control: Losartan vs Test: Fimasartan: serious adverse events5 of 2503 of 255505NCT00922480Trial comparisons
LCZ696 200 mg vs Olmesartan 20 mg: Number of Patients Achieving Successful Mean Sitting Diastolic Blood Pressure (msDBP) Control133 of 188112 of 187375NCT01876368Trial comparisons
LCZ696 200 mg vs Olmesartan 20 mg: Number of Patients Achieving Successful Mean Sitting Diastolic Blood Pressure (msDBP) Response137 of 188115 of 187375NCT01876368Trial comparisons
LCZ696 200 mg vs Olmesartan 20 mg: Number of Patients Achieving Successful Mean Sitting Systolic Blood Pressure (msSBP) Control84 of 18858 of 187375NCT01876368Trial comparisons
LCZ696 200 mg vs Olmesartan 20 mg: Number of Patients Achieving Successful Mean Sitting Systolic Blood Pressure (msSBP) Response90 of 18865 of 187375NCT01876368Trial comparisons
LCZ696 200 mg vs Olmesartan 20 mg: Number of Patients Achieving Successful Overall Blood Pressure Control76 of 18852 of 187375NCT01876368Trial comparisons
LCZ696 200 mg vs Olmesartan 20 mg: serious adverse events0 of 1882 of 187375NCT01876368Trial comparisons
LCZ696 Monotherapy vs LCZ696 Combination Therapy: Number of Participants With Blood Pressure Control Rate of <140/90 mmHg (Analysis by Mono or Combination Therapy)176 of 22880 of 112340NCT01256411Trial comparisons
MK-0954A vs Losartan: serious adverse events0 of 1660 of 170336NCT01307046Trial comparisons
L50/H12.5/A5 vs L50 + A5: serious adverse events1 of 1641 of 163327NCT01302691Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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