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Disease · MONDO_0001475

Comparisons in its trials40

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Arm 1: SPI-2012 and TC vs Arm 2: Pegfilgrastim and TC: Number of Participants With Neutropenic Complications in Cycle 18 of 1968 of 210406NCT02643420Trial comparisons
Arm 1: SPI-2012 and TC vs Arm 2: Pegfilgrastim and TC: Number of Participants With Febrile Neutropenia (FN) in Cycle 14 of 1962 of 210406NCT02643420Trial comparisons
(Arm 1): SPI-2012 and TC vs (Arm 2): Pegfilgrastim and TC: Number of Participants With Febrile Neutropenia (FN) in Cycle 11 of 1184 of 119237NCT02953340Trial comparisons
(Arm 1): SPI-2012 and TC vs (Arm 2): Pegfilgrastim and TC: Number of Participants With Neutropenic Complications in Cycle 11 of 1185 of 119237NCT02953340Trial comparisons
Immediate Voriconazole vs Deferred Voriconazole Treatment: serious adverse events8 of 818 of 66147NCT00150345Trial comparisons
Immediate Voriconazole vs Deferred Voriconazole Treatment: Number of Participants Assessed as Needing Further Antineoplastic Therapy as Planned42 of 6832 of 54122NCT00150345Trial comparisons
Immediate Voriconazole vs Deferred Voriconazole Treatment: Number of Participants With Defervescence Day 5 (4 Days After Initiation of Study Treatment)32 of 6828 of 54122NCT00150345Trial comparisons
Granulocyte Arm vs Control Arm: Long-term Survival20 of 5630 of 58114NCT00627393Trial comparisons
Granulocyte Arm vs Control Arm: serious adverse events26 of 5625 of 58114NCT00627393Trial comparisons
Ceftolozane/Tazobactam Arm vs Standard of Care (SOC) Arm: Number of Participants With Infection-related Mortality in the MITT Analysis Set at LFU0 of 470 of 5097NCT03485950Trial comparisons
Ceftolozane/Tazobactam Arm vs Standard of Care (SOC) Arm: Number of Participants With Favorable Clinical Response in the MITT Analysis Set at TOC34 of 4728 of 5097NCT03485950Trial comparisons
Ceftolozane/Tazobactam Arm vs Standard of Care (SOC) Arm: 30 Day All-cause Mortality in the MITT Analysis Set2 of 472 of 5097NCT03485950Trial comparisons
Ceftolozane/Tazobactam Arm vs Standard of Care (SOC) Arm: Number of Participants With Favorable Clinical Response at End of Inpatient Intravenous Therapy (EOIV)41 of 4736 of 5097NCT03485950Trial comparisons
Ceftolozane/Tazobactam Arm vs Standard of Care (SOC) Arm: Number of Participants With Infection-related Mortality in the MITT Analysis Set at TOC0 of 470 of 5097NCT03485950Trial comparisons
Ceftolozane/Tazobactam Arm vs Standard of Care (SOC) Arm: Number of Participants With Favorable Clinical Response in the MITT Analysis Set at Late Follow-Up (LFU)33 of 4726 of 5097NCT03485950Trial comparisons
Ceftolozane/Tazobactam Arm vs Standard of Care (SOC) Arm: deaths from any cause3 of 472 of 5097NCT03485950Trial comparisons
Ceftolozane/Tazobactam Arm vs Standard of Care (SOC) Arm: serious adverse events33 of 4733 of 5097NCT03485950Trial comparisons
Immediate Voriconazole vs Deferred Voriconazole Treatment: Number of Participants With Proven or Probable Invasive Fungal Infections (IFI): Complete Case Analysis6 of 439 of 3578NCT00150345Trial comparisons
Methotrexate vs Cyclophosphamide: serious adverse events56 of 598 of 1675NCT00003910Trial comparisons
Immediate Voriconazole vs Deferred Voriconazole Treatment: Number of Participants That Died on or Before Day 28 (Mortality)4 of 431 of 2972NCT00150345Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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