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Disease · MONDO_0003219

Comparisons in its trials80

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Tislelizumab + Chemotherapy vs Placebo + Chemotherapy: deaths from any cause397 of 501431 of 496997NCT03777657Trial comparisons
Tislelizumab + Chemotherapy vs Placebo + Chemotherapy: serious adverse events211 of 498179 of 494992NCT03777657Trial comparisons
Cetuximab Plus Capecitabine Plus Cisplatin vs Capecitabine Plus Cisplatin: Safety - Number of Participants With Adverse Events (AEs)446 of 446432 of 436882NCT00678535Trial comparisons
Cetuximab Plus Capecitabine Plus Cisplatin vs Capecitabine Plus Cisplatin: serious adverse events239 of 446194 of 436882NCT00678535Trial comparisons
Napabucasin + Paclitaxel vs Placebo + Paclitaxel: Number of Patients With Adverse Events352 of 357338 of 350707NCT02178956Trial comparisons
Napabucasin + Paclitaxel vs Placebo + Paclitaxel: deaths from any cause286 of 357275 of 350707NCT02178956Trial comparisons
Napabucasin + Paclitaxel vs Placebo + Paclitaxel: serious adverse events125 of 357101 of 350707NCT02178956Trial comparisons
Ramucirumab and Paclitaxel vs Placebo and Paclitaxel: serious adverse events161 of 327146 of 329656NCT01170663Trial comparisons
Ramucirumab + Cisplatin + Capecitabine vs Placebo + Cisplatin + Capecitabine: Number of Participants With Anti-Ramucirumab Antibodies4 of 3235 of 315638NCT02314117Trial comparisons
LY3009806+Capecitabine+Cisplatin vs Placebo+Capecitabine+Cisplatin: serious adverse events161 of 323150 of 315638NCT02314117Trial comparisons
Pembrolizumab vs Chemotherapy: Number of Participants Experiencing an Adverse Event (AE)301 of 314288 of 296610NCT02564263Trial comparisons
Pembrolizumab vs Chemotherapy: Number of Participants Discontinuing Study Treatment Due an Adverse Event (AE)40 of 31442 of 296610NCT02564263Trial comparisons
Napabucasin + Paclitaxel vs Placebo + Paclitaxel: Objective Response Rate16 of 28918 of 283572NCT02178956Trial comparisons
Napabucasin + Paclitaxel vs Placebo + Paclitaxel: Disease Control Rate55 of 28958 of 283572NCT02178956Trial comparisons
mFOLFOX6 + Zolbetuximab vs mFOLFOX6+ Placebo: Number of Participants With Treatment Emergent Adverse Events (TEAEs)278 of 279277 of 278557NCT03504397Trial comparisons
Surgery + Adjuvant Chemotherapy (SC) vs Neoadjuvant Chemotherapy +Surgery +Adjuvant Chemotherapy (CSC): deaths from any cause91 of 26478 of 266530NCT01515748Trial comparisons
CAPOX+ Zolbetuximab vs CAPOX+ Placebo: Number of Participants With Treatment Emergent Adverse Events (TEAEs)251 of 254244 of 249503NCT03653507Trial comparisons
CapeOx Plus Lapatinib vs CapeOx Plus Placebo: Percentage of Participants With Clinical Benefit (CB)199 of 249188 of 238487NCT00680901Trial comparisons
CapeOx Plus Lapatinib vs CapeOx Plus Placebo: Percentage of Participants With a Confirmed Complete Response (CR) or a Partial Response (PR)131 of 24994 of 238487NCT00680901Trial comparisons
8 mg/kg Ramucirumab + 80 mg/m² Paclitaxel vs Placebo + 80 mg/m² Paclitaxel: deaths from any cause246 of 294123 of 146440NCT02898077Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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