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Disease · MONDO_0005021

Trials24

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 7 more are not shown, since the checks do not confirm them.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT03439514A Study of ARRY-371797 (PF-07265803) in Patients With Symptomatic Dilated Cardiomyopathy Due to a Lamin A/C Gene MutationPhase 3772024-01-09Dilated Cardiomyopathy, Lamin A/C Gene MutationARRY-797Its record names the diseaseClinicalTrials.gov
NCT04572893Exploratory Study of Danicamtiv in Patients With Primary Dilated Cardiomyopathy (DCM) Due to Genetic Variants or Other CausalitiesPhase 2412025-05-21Primary Familial Dilated CardiomyopathyDANICAMTIVIts record names the diseaseClinicalTrials.gov
NCT00741156The Acute Effects of the Angiotensin-converting Enzyme Inhibitor Enalaprilat on Flow DistributionPhase 3122015-12-18Hypertension, Congestive CardiomyopathyENALAPRILATIts record names the diseaseClinicalTrials.gov
NCT02351856A Rollover Study of ARRY-371797 in Patients With LMNA-Related Dilated CardiomyopathyPhase 282022-03-31LMNA-Related Dilated CardiomyopathyARRY-797Its record names the diseaseClinicalTrials.gov
NCT07210723A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated CardiomyopathyPhase 2/3332Symptomatic Genetic Dilated CardiomyopathyDANICAMTIVIts record names the diseaseClinicalTrials.gov
NCT06632834Outcome-targeted Therapy: Principle and Outcome Evaluation: Clinical Study and Phenotype-genotype CorrelationPhase 2230Dilated CardiomyopathySIMVASTATINIts record names the diseaseClinicalTrials.gov
NCT06250257Bromocriptine in Dilated Cardiomyopathy Among Women of Reproductive AgePhase 3112Dilated CardiomyopathyBROMOCRIPTINEIts record names the diseaseClinicalTrials.gov
NCT02654678Follow-up Safety Trial in Children With Chronic Heart Failure Therapy Receiving Orodispersible Minitablets of EnalaprilPhase 2/3100Heart Failure, Dilated Cardiomyopathy, Congenital Heart DiseaseENALAPRILIts record names the diseaseClinicalTrials.gov
NCT05193838Effect of Allopurinol on Left Ventricular Function in Children With Dilated Cardiomyopathy100Dilated CardiomyopathyALLOPURINOLIts record names the diseaseClinicalTrials.gov
NCT01857856PHOspholamban RElated CArdiomyopathy STudy - InterventionPhase 384Phospholamban R14del Mutation-related CardiomyopathyEPLERENONEIts record names the diseaseClinicalTrials.gov
NCT00505154Effect of Rosuvastatin on Left Ventricular RemodelingPhase 375Dilated CardiomyopathyROSUVASTATINIts record names the diseaseClinicalTrials.gov
NCT02652728Orodispersible Minitablets of Enalapril in Children With Heart Failure Due to Dilated CardiomyopathyPhase 2/350Heart Failure, Dilated CardiomyopathyENALAPRILIts record names the diseaseClinicalTrials.gov
NCT03779646Bisoprolol in DMD Early CardiomyopathyPhase 2/342Duchenne Muscular Dystrophy, Cardiomyopathy, DilatedBISOPROLOLIts record names the diseaseClinicalTrials.gov
NCT00765518Use of Ixmyelocel-T (Formerly Cardiac Repair Cell [CRC] Treatment) in Patients With Heart Failure Due to Dilated Cardiomyopathy (IMPACT-DCM)Phase 240Dilated CardiomyopathyIXMYELOCEL-TIts record names the diseaseClinicalTrials.gov
NCT00501514Effects of Growth Hormone on Exercise CapacityPhase 322Chronic Heart FailureSOMATROPINIts record names the diseaseClinicalTrials.gov
NCT01020968Use of Ixmyelocel-T (Formerly Catheter-based Cardiac Repair Cell [CRC]) Treatment in Patients With Heart Failure Due to Dilated CardiomyopathyPhase 222Dilated CardiomyopathyIXMYELOCEL-TIts record names the diseaseClinicalTrials.gov
NCT00709163Nesiritide - Dilated CardiomyopathyNot applicable20Dilated CardiomyopathyNESIRITIDEIts record names the diseaseClinicalTrials.gov
NCT02057341A Study of ARRY-371797 in Patients With LMNA-Related Dilated CardiomyopathyPhase 212LMNA-Related Dilated CardiomyopathyARRY-797Its record names the diseaseClinicalTrials.gov
NCT02133911A Pilot Trial of Ranolazine to Treat Patients With Dilated CardiomyopathyPhase 210Dilated CardiomyopathyRANOLAZINEIts record names the diseaseClinicalTrials.gov
NCT04405804Early Administration of Ivabradine in Children With Heart FailurePhase 29Acute Heart Failure, Dilated CardiomyopathyIVABRADINEIts record names the diseaseClinicalTrials.gov

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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