Disease · MONDO_0005114

pneumococcal infection

6 sourcesdiseases-2026-09-18-0.1.0

Cite this record

ConductScience Library. pneumococcal infection. Diseases, record MONDO_0005114. Release diseases-2026-09-18-0.1.0, 18 Sept 2026. https://conductscience.org/library/diseases/MONDO_0005114

On this page

Disease

Names and IDs as Open Targets gives them. Its IDs in MeSH, Orphanet, the Disease Ontology and the NCI Thesaurus are those Open Targets states for it.

Name: pneumococcal infection; Open Targets
Open Targets ID: MONDO_0005114; Open Targets
Other names: INFECT PNEUMOCOCCAL, INFECT STREP PNEUMONIAE, Infection, Pneumococcal, Infection, Streptococcus pneumoniae, Infections, Pneumococcal, Infections, Streptococcus pneumoniae, PNEUMOCOCCAL INFECT, Pneumococcal Infections, Pneumococcal infection, NOS, Pneumococcal infectious disease (disorder), Pneumococcal infectious disease, NOS, STREP PNEUMONIAE INFECT, Streptococcus pneumoniae Infection, Streptococcus pneumoniae Infections, Streptococcus pneumoniae caused disease or disorder, Streptococcus pneumoniae disease or disorder, Streptococcus pneumoniae infectious disease, pneumococcal infectious disease, pneumoniae Infection, Streptococcus, pneumoniae Infections, Streptococcus; Open Targets
MeSH: D011008; MeSH
Highest stage of its drugs: Approval, for 1 of its 5 drugs, from FDA; Open Targets

Drugs5

The drugs Open Targets' clinical reports study for the disease, the highest stage first, then the most trial reports. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

Drug	ChEMBL ID	Type	Open Targets' stage	Stage reported by	Reports	Of them trials	Trials shown here	Source
STREPTOCOCCUS PNEUMONIAE POLYSACCHARIDE CONJUGATED TO CORYNEBACTERIUM DIPHTHERIAE CRM197	CHEMBL6068493	Vaccine component	Approval	FDA	8	6	1	Drugs and targets
KP-1461	CHEMBL4297297	Small molecule	Phase 2	TTD	1	0	0	Drugs and targets
AMOXICILLIN	CHEMBL1082	Small molecule	Unknown	ClinicalTrials.gov	1	1	1	Drugs and targets
INFLUENZA A VIRUS, SPLIT VIRION	CHEMBL6068363	Vaccine component	Unknown	ClinicalTrials.gov	1	1	0	Drugs and targets
INFLUENZA VIRUS VACCINE	CHEMBL2109042	Vaccine component	Unknown	ClinicalTrials.gov	1	1	0	Drugs and targets

Targets0

The targets ChEMBL's mechanism records give for the disease's drugs, through Open Targets, the most drugs first. A mechanism record says what a drug acts on, not that the target causes the disease.

None in this release.

Trials2

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 6 more are not shown, since the checks do not confirm them.

Trial	Title	Phase	Participants	Results first posted	Conditions	Drugs	Linked by	Source
NCT01509105	Prevenar13 Post Market Surveillance		649	2017-02-13	Healthy	STREPTOCOCCUS PNEUMONIAE POLYSACCHARIDE CONJUGATED TO CORYNEBACTERIUM DIPHTHERIAE CRM197	Its record names the disease	ClinicalTrials.gov
NCT05361499	A Controlled Human Pneumococcal Infection Model (PIM) Study	Not applicable	20		Streptococcus Pneumoniae Infection	AMOXICILLIN	Its record names the disease	ClinicalTrials.gov

Comparisons in its trials0

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

None in this release.

Papers from its trials0

The papers the trials shown here list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

None in this release.

Data dates

The date of each source this release read.

Open Targets: 2026-09-18; Open Targets
Drug links and their checks, from Drugs and targets: 2026-09-18; Drugs and targets
ClinicalTrials.gov, from Trials: 2026-11-12; Trials
Comparisons, from Trial comparisons: 2026-03-23; Trial comparisons
PubMed, for the checks: 2026-11-06; PubMed
MeSH, for the checks: 2026-11-10; MeSH

Sources 6

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
NLM's MeSHNLM's terms
Open TargetsCC0 1.0
PubMedNLM's terms

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
NLM's MeSHNLM's
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this disease from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0005114

GET https://conductscience.org/api/diseases/v1/MONDO_0005114/drugs

API reference For AI assistants