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Disease · MONDO_0005420

Comparisons in its trials17

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Armour® Thyroid vs Levothyroxine: deaths from any cause1 of 1411 of 143284NCT04124705Trial comparisons
Armour® Thyroid vs Levothyroxine: serious adverse events4 of 1417 of 143284NCT04124705Trial comparisons
Radioiodine vs Control: deaths from any cause1 of 510 of 50101NCT03880578Trial comparisons
Radioiodine vs Control: serious adverse events0 of 510 of 50101NCT03880578Trial comparisons
Treatment Period: Tirosint Capsules vs Run-in Period: LT4 Tablets: deaths from any cause0 of 470 of 4794NCT03094416Trial comparisons
Treatment Period: Tirosint Capsules vs Run-in Period: LT4 Tablets: serious adverse events1 of 472 of 4794NCT03094416Trial comparisons
All Participants vs Participants Who Entered Maintenance Period: Proportion of Participants With Normalized TSH at End of Maintenance Period31 of 4631 of 4288NCT05823012Trial comparisons
All Participants vs Participants Who Entered the Maintenance Period: Proportion of Participants With Normalized TSH Throughout the Maintenance Period27 of 4627 of 4288NCT05823012Trial comparisons
2 Tablet Increase vs 3 Tablet Increase: the Participants in Each Arm Who Required Levothyroxine Dose Adjustments (Either Increased or Decreased) Occurred to Maintain a Euthyroid State10 of 2516 of 2348NCT00230802Trial comparisons
2 Tablet Increase vs 3 Tablet Increase: Proportion of Subjects With Abnormal Thyroid Stimulating Hormone Values When Following an Every 4 Week Monitoring Schedule During Pregnancy.25 of 2523 of 2348NCT00230802Trial comparisons
2 Tablet Increase vs 3 Tablet Increase: Proportion of Patients in Each Treatment Arm Euthyroid Through Gestation24 of 2521 of 2348NCT00230802Trial comparisons
2 Tablet Increase vs 3 Tablet Increase: serious adverse events0 of 250 of 2348NCT00230802Trial comparisons
Levothyroxine Period vs Liothyronine Period: serious adverse events0 of 140 of 1428NCT00106119Trial comparisons
Single Therapy vs Combination Therapy: deaths from any cause0 of 70 of 613NCT04782856Trial comparisons
Single Therapy vs Combination Therapy: serious adverse events0 of 70 of 613NCT04782856Trial comparisons
Liquid Stable Levothyroxine (l-T4) TirosintSOL First, Then Oral Tablet Levothyroxine (L-T4) vs Oral Tablet Levothyroxine (L-T4) First, Then Liquid Stable Levothyroxine (L-T4) Tirosint-SOL: deaths from any cause
0 of 20 of 46NCT04747275Trial comparisons
Liquid Stable Levothyroxine (l-T4) TirosintSOL First, Then Oral Tablet Levothyroxine (L-T4) vs Oral Tablet Levothyroxine (L-T4) First, Then Liquid Stable Levothyroxine (L-T4) Tirosint-SOL: serious adverse events
0 of 20 of 46NCT04747275Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

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