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Disease · MONDO_0006572

Comparisons in its trials13

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Ruxolitinib Cream 1.5% BID vs Vehicle Cream BID: deaths from any cause0 of 600 of 3292NCT05593432Trial comparisons
Ruxolitinib Cream 1.5% BID vs Vehicle Cream BID: serious adverse events0 of 600 of 3292NCT05593432Trial comparisons
Double-Blind, Vehicle-Controlled Period: Ruxolitinib Cream 1.5% BID vs Double-Blind, Vehicle-Controlled Period: Vehicle Cream BID: Number of Participants With Any Treatment-emergent Adverse Event (TEAE) During the Double-blind, Vehicle-controlled Period
15 of 319 of 3263NCT05593432Trial comparisons
Double-Blind, Vehicle-Controlled Period: Ruxolitinib Cream 1.5% BID vs Double-Blind, Vehicle-Controlled Period: Vehicle Cream BID: Number of Participants With Any ≥Grade 3 TEAE During the Double-blind, Vehicle-controlled Period
0 of 310 of 3263NCT05593432Trial comparisons
Open-Label Extension Period: Ruxolitinib Cream 1.5% BID vs Open-Label Extension Period: Vehicle Cream to Ruxolitinib Cream 1.5% BID: Number of Participants With Any ≥Grade 3 TEAE During the Open-label Extension Period
0 of 301 of 2959NCT05593432Trial comparisons
Open-Label Extension Period: Ruxolitinib Cream 1.5% BID vs Open-Label Extension Period: Vehicle Cream to Ruxolitinib Cream 1.5% BID: Number of Participants With Any TEAE During the Open-label Extension Period
8 of 3011 of 2959NCT05593432Trial comparisons
KPL-716 vs Placebo: deaths from any cause0 of 390 of 1958NCT03858634Trial comparisons
KPL-716 vs Placebo: serious adverse events1 of 390 of 1958NCT03858634Trial comparisons
Etanercept vs Placebo Injection: serious adverse events1 of 240 of 1438NCT00285779Trial comparisons
Etanercept vs Placebo Injection: Count of Patients Achieving a Response in Cutaneous or Mucosal Disease at 24 Weeks4 of 135 of 1427NCT00285779Trial comparisons
Pimecrolimus 1% Cream vs Vehicle Cream: serious adverse events0 of 100 of 1121NCT00297037Trial comparisons
Cutaneous LP vs Dose Escalation Extension Group: deaths from any cause0 of 120 of 517NCT05188521Trial comparisons
Cutaneous LP vs Dose Escalation Extension Group: serious adverse events1 of 120 of 517NCT05188521Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0006572/comparisons