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Disease · MONDO_0008170

Comparisons in its trials178

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Nintedanib vs Placebo: serious adverse events379 of 902157 of 4501,352NCT01015118Trial comparisons
Atezolizumab With Paclitaxel, Carboplatin and Bevacizumab vs Placebo With Paclitaxel, Carboplatin and Bevacizumab: deaths from any cause272 of 651289 of 6501,301NCT03038100Trial comparisons
Atezolizumab With Paclitaxel, Carboplatin and Bevacizumab vs Placebo With Paclitaxel, Carboplatin and Bevacizumab: serious adverse events304 of 642215 of 6441,286NCT03038100Trial comparisons
Niraparib vs Placebo: deaths from any cause48 of 48431 of 244728NCT02655016Trial comparisons
Niraparib vs Placebo: serious adverse events156 of 48432 of 244728NCT02655016Trial comparisons
Trabectedin/DOXIL vs DOXIL: serious adverse events133 of 333102 of 330663NCT00113607Trial comparisons
Pembrolizumab + Paclitaxel ± Bevacizumab vs Placebo + Paclitaxel ± Bevacizumab: deaths from any cause225 of 322244 of 321643NCT05116189Trial comparisons
Pembrolizumab + Paclitaxel ± Bevacizumab vs Placebo + Paclitaxel ± Bevacizumab: serious adverse events178 of 320122 of 318638NCT05116189Trial comparisons
Rucaparib 600 mg Tablets vs Placebo Tablets: deaths from any cause9 of 3722 of 189561NCT01968213Trial comparisons
Rucaparib 600 mg Tablets vs Placebo Tablets: serious adverse events91 of 37220 of 189561NCT01968213Trial comparisons
Paclitaxel + Carboplatin Followed 4 Weeks Later by Paclitaxel vs Paclitaxel + Carboplatin Followed by Observation: Overall Survival44 of 27453 of 268542NCT00003644Trial comparisons
Paclitaxel + Carboplatin Followed 4 Weeks Later by Paclitaxel vs Paclitaxel + Carboplatin Followed by Observation: deaths from any cause44 of 27453 of 268542NCT00003644Trial comparisons
Paclitaxel + Carboplatin Followed 4 Weeks Later by Paclitaxel vs Paclitaxel + Carboplatin Followed by Observation: serious adverse events7 of 2745 of 268542NCT00003644Trial comparisons
Part 1 Overall vs Part 2 Overall: deaths from any cause2 of 20418 of 287491NCT01891344Trial comparisons
Part 1 Overall vs Part 2 Overall: serious adverse events54 of 20492 of 287491NCT01891344Trial comparisons
Mirvetuximab Soravtansine vs Investigator's Choice (IC) Chemotherapy: deaths from any cause162 of 227177 of 226453NCT04209855Trial comparisons
Mirvetuximab Soravtansine vs Investigator's Choice (IC) Chemotherapy: serious adverse events62 of 22773 of 226453NCT04209855Trial comparisons
Lurbinectedin vs Control (PLD or Topotecan): deaths from any cause170 of 219171 of 213432NCT02421588Trial comparisons
Lurbinectedin vs Control (PLD or Topotecan): serious adverse events92 of 21985 of 213432NCT02421588Trial comparisons
Mirvetuximab Soravtansine vs Investigator's Choice (IC) Chemotherapy: Number of Participants With Treatment-emergent Adverse Events (TEAEs)211 of 218194 of 207425NCT04209855Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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