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Disease · MONDO_0100192

Trials12

Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs. 3 more are not shown, since the checks do not confirm them.

TrialTitlePhaseParticipantsResults first postedConditionsDrugsLinked bySource
NCT02193867Clinical Study In Infants With Rapidly Progressive Lysosomal Acid Lipase DeficiencyPhase 2102019-11-18Lysosomal Acid Lipase DeficiencySEBELIPASE ALFAIts record names the diseaseClinicalTrials.gov
NCT00162552Clinical Trial of Pentoxifylline in Patient With CirrhosisPhase 3342Cirrhosis, Liver FailurePENTOXIFYLLINEIts record names the diseaseClinicalTrials.gov
NCT01997658Preoperative Glucocorticoid Use in Major HepatectomyPhase 2/3200ComplicationsMETHYLPREDNISOLONEIts record names the diseaseClinicalTrials.gov
NCT03563378Effects of Intraoperative Normal Saline vs Lactated Ringer on Outcomes in Pediatric Liver TransplantationNot applicable200Biliary Atresia Intrahepatic Syndromic FormSODIUM CHLORIDEIts record names the diseaseClinicalTrials.gov
NCT03957629Optimized Treatment of Peginterferon Alfa 2a in Treatment Experienced Patients With HBV Related Liver FibrosisNot applicable186Hepatitis B, Liver FibrosisPEGINTERFERON ALFA-2A, TENOFOVIR DISOPROXIL FUMARATEIts record names the diseaseClinicalTrials.gov
NCT03920618Three Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLFNot applicable150Hepatitis B, Acute-On-Chronic Liver FailureENTECAVIR, TENOFOVIR ALAFENAMIDE, TENOFOVIR DISOPROXIL FUMARATEIts record names the diseaseClinicalTrials.gov
NCT06307808Viral Immunity in Solid Organ Transplant Recipients: Monitoring Of The Response To Hepatitis B Booster Vaccination66HBV, Kidney Transplantation, Liver TransplantationBELATACEPT, TACROLIMUSIts record names the diseaseClinicalTrials.gov
NCT02689245Randomized Controlled Trial Comparing the Efficacy and Safety of FMT in Hepatitis B Reactivation Leads to Acute on Chronic Liver Failure.Not applicable64Acute on Chronic Liver FailureTENOFOVIRIts record names the diseaseClinicalTrials.gov
NCT07085806To Study Effect of Injection Pentoxifylline on Liver Growth After Major Liver SurgeryNot applicable60Liver RegenerationPENTOXIFYLLINEIts record names the diseaseClinicalTrials.gov
NCT01726465Methylprednisolone N Acetylcysteine in Hepatic ResectionsPhase 250Ischemic Reperfusion Injury, Insufficiency; Hepatic, Postoperative, Liver TumourMETHYLPREDNISOLONEIts record names the diseaseClinicalTrials.gov
NCT00225901Phase I/II Study of Recombinant Human Hepatocyte Growth Factor in Fulminant Hepatic FailurePhase 1/216Liver Failure, AcuteHEPATOPOIETIN-AIts record names the diseaseClinicalTrials.gov
NCT07519005Ex Vivo Perfusion of Gene-Edited Porcine Livers in Patients With Severe Hepatic FailureEarly phase 11Hepatic FailureECULIZUMAB, ETANERCEPT, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, RITUXIMAB, TACROLIMUSIts record names the diseaseClinicalTrials.gov

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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