Disease · MONDO_0100338
Trials74
Trials an Open Targets clinical report links to the disease, posted results first, then the largest. A trial is shown when the release's checks confirm its link to the disease and Drugs and targets shows its link to one of the disease's drugs.
1 to 20 of 74
Download this page as JSON| Trial | Title | Phase | Participants | Results first posted | Conditions | Drugs | Linked by | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01426191 | Study on Cefotaxime and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection | 2,032 | 2019-10-04 | Respiratory Tract Infections, Urinary Tract Infections | CEFOTAXIME SODIUM, SULBACTAM SODIUM | Its record names the disease | ClinicalTrials.gov | |
| NCT04187144 | Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI) | Phase 3 | 1,606 | 2023-07-18 | Urinary Tract Infections | GEPOTIDACIN, NITROFURANTOIN | Its record names the disease | ClinicalTrials.gov |
| NCT04020341 | A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI) | Phase 3 | 1,531 | 2023-06-22 | Urinary Tract Infections | GEPOTIDACIN, NITROFURANTOIN | Its record names the disease | ClinicalTrials.gov |
| NCT03788967 | Study to Assess the Efficacy, Safety and Pharmacokinetics of Orally Administered Tebipenem Pivoxil Hydrobromide (SPR994) Compared to Intravenous Ertapenem in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) | Phase 3 | 1,372 | 2022-07-25 | Complicated Urinary Tract Infection, Acute Pyelonephritis | ERTAPENEM, TEBIPENEM PIVOXIL HYDROBROMIDE | Open Targets' reading, confirmed by NLM's indexing of its papers | ClinicalTrials.gov |
| NCT03032510 | Efficacy and Safety Study of Eravacycline Compared With Ertapenem in Participants With Complicated Urinary Tract Infections | Phase 3 | 1,205 | 2019-10-02 | Complicated Urinary Tract Infections | ERAVACYCLINE, ERTAPENEM | Its record names the disease | ClinicalTrials.gov |
| NCT01595529 | The SCOUT Study: "Short Course Therapy for Urinary Tract Infections in Children" | Phase 2 | 717 | 2020-07-13 | Urinary Tract Infection | CEFIXIME, CEPHALEXIN, TRIMETHOPRIM | Its record names the disease | ClinicalTrials.gov |
| NCT02486627 | A Study of Plazomicin Compared With Meropenem for the Treatment of Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis (AP) | Phase 3 | 609 | 2018-08-23 | Complicated Urinary Tract Infection, Acute Pyelonephritis | MEROPENEM, PLAZOMICIN | Open Targets' reading, confirmed by NLM's indexing of its papers | ClinicalTrials.gov |
| NCT01345929 | Study Comparing the Safety and Efficacy of Intravenous CXA-201 and Intravenous Levofloxacin in Complicated Urinary Tract Infection, Including Pyelonephritis | Phase 3 | 558 | 2015-01-15 | Complicated Urinary Tract Infection, Pyelonephritis | CEFTOLOZANE, LEVOFLOXACIN, TAZOBACTAM | Open Targets' reading, confirmed by NLM's indexing of its papers | ClinicalTrials.gov |
| NCT05630833 | A Study to Investigate the Efficacy and Safety With Gepotidacin in Japanese Female Participants With Uncomplicated Urinary Tract Infection (Acute Cystitis) | Phase 3 | 380 | 2025-03-17 | Urinary Tract Infections | GEPOTIDACIN | Its record names the disease | ClinicalTrials.gov |
| NCT01644643 | Ceftazidime-Avibactam for the Treatment of Infections Due to Ceftazidime Resistant Pathogens | Phase 3 | 345 | 2015-12-14 | Complicated Urinary Tract Infection, Complicated Intra-abdominal Infection | AVIBACTAM, CEFTAZIDIME | Open Targets' reading, confirmed by NLM's indexing of its papers | ClinicalTrials.gov |
| NCT00976963 | Single Dose Monurol for Treatment of Acute Cystitis | Not applicable | 300 | 2023-06-05 | Urinary Tract Infection | FOSFOMYCIN | Its record names the disease | ClinicalTrials.gov |
| NCT03366207 | Efficacy of Ciprofloxacin for the Treatment of Uncomplicated Urinary Tract Infection (uUTI) | Phase 4 | 250 | 2019-08-21 | UTI - Lower Urinary Tract Infection, Antibiotic Resistant Infection | CIPROFLOXACIN | Its record names the disease | ClinicalTrials.gov |
| NCT00549939 | Alfuzosin Treatment in Children and Adolescents With Neurogenic Urinary Bladder Dysfunction | Phase 3 | 172 | 2011-02-08 | Neurogenic Urinary Bladder | ALFUZOSIN | Its record names the disease | ClinicalTrials.gov |
| NCT01096849 | A Study of Plazomicin Compared With Levofloxacin for the Treatment of Complicated Urinary Tract Infection (cUTI) and Acute Pyelonephritis (AP) | Phase 2 | 145 | 2018-08-22 | Complicated Urinary Tract Infection, Acute Pyelonephritis | LEVOFLOXACIN, PLAZOMICIN | Open Targets' reading, confirmed by NLM's indexing of its papers | ClinicalTrials.gov |
| NCT01923129 | Optimal Duration of Indwelling Urinary Catheter Following Pelvic Surgery | Not applicable | 142 | 2019-02-20 | Urinary Retention | PRAZOSIN | Its record names the disease | ClinicalTrials.gov |
| NCT00690378 | Comparative Study of NXL104/Ceftazidime Versus Comparator in Adults With Complicated Urinary Tract Infections | Phase 2 | 137 | 2018-05-25 | Complicated Urinary Tract Infection | AVIBACTAM, CEFTAZIDIME | Open Targets' reading, confirmed by NLM's indexing of its papers | ClinicalTrials.gov |
| NCT03230838 | MK-7625A Versus Meropenem in Pediatric Participants With Complicated Urinary Tract Infection (cUTI) (MK-7625A-034) | Phase 2 | 134 | 2021-12-01 | Complicated Urinary Tract Infection, Pyelonephritis | CEFTOLOZANE, TAZOBACTAM | Open Targets' reading, confirmed by NLM's indexing of its papers | ClinicalTrials.gov |
| NCT00921024 | Safety and Efficacy of IV CXA-101 and IV Ceftazidime in Patients With Complicated Urinary Tract Infections | Phase 2 | 129 | 2015-01-15 | Complicated Urinary Tract Infection | CEFTAZIDIME, CEFTOLOZANE | Open Targets' reading of its record | ClinicalTrials.gov |
| NCT02728089 | Study of Ceftolozane/Tazobactam (MK-7625A) in Japanese Participants With Uncomplicated Pyelonephritis and Complicated Urinary Tract Infection (MK-7625A-014) | Phase 3 | 115 | 2018-09-19 | Urinary Tract Infection (UTI), Complicated Urinary Tract Infection, Pyelonephritis, Uncomplicated Pyelonephritis | CEFTOLOZANE | Open Targets' reading of its record | ClinicalTrials.gov |
| NCT06597344 | A Study in Adolescent and Adult Female Participants to Evaluate Clinical Symptom Improvement and the Safety of Gepotidacin During Treatment of Uncomplicated Urinary Tract Infections (Acute Cystitis) | Phase 3 | 97 | 2026-02-11 | Urinary Tract Infections | GEPOTIDACIN | Its record names the disease | ClinicalTrials.gov |
diseases-2026-09-18-0.1.0
Sources 6
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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