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Disease · MONDO_0810000

Comparisons in its trials13

Comparisons Trial comparisons calculated in the trials shown here, most participants first. A comparison in one of these trials does not always compare a treatment for the disease, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Brolucizumab 6mg vs Aflibercept 2mg: deaths from any cause4 of 3707 of 369739NCT02434328Trial comparisons
Brolucizumab 6mg vs Aflibercept 2mg: serious adverse events79 of 37089 of 369739NCT02434328Trial comparisons
Ranibizumab Non-ANCHOR vs Ranibizumab ANCHOR: serious adverse events80 of 5134 of 18531NCT00331864Trial comparisons
Verteporfin + Ranibizumab vs Ranibizumab: serious adverse events25 of 12228 of 133255NCT00433017Trial comparisons
Ranibizumab vs Sham Control: Number of Participants With Requirement for Rescue Treatment at Month 10 of 1191 of 58177NCT01840410Trial comparisons
Group I vs Group II: deaths from any cause0 of 300 of 3060NCT00527475Trial comparisons
Group I vs Group II: serious adverse events0 of 300 of 3060NCT00527475Trial comparisons
ICON-1 Maintenance Therapy vs ICON-1 Combination Therapy: deaths from any cause0 of 70 of 815NCT03452527Trial comparisons
ICON-1 Maintenance Therapy vs ICON-1 Combination Therapy: serious adverse events2 of 71 of 815NCT03452527Trial comparisons
Ranibizumab Dose A vs Ranibizumab Dose B: Number of Subjects Avoiding 15 or More Letter Loss of Best Corrected Visual Acuity From Baseline to 12 Months on an Early Treatment Diabetic Retinopathy Study (ETDRS) Visual Acuity Chart Measured at 4 Meters.
5 of 52 of 27NCT00363168Trial comparisons
Ranibizumab Dose A vs Ranibizumab Dose B: Number of Subjects Experiencing Complications Related to Drug or Its Administration0 of 50 of 27NCT00363168Trial comparisons
Ranibizumab Dose A vs Ranibizumab Dose B: serious adverse events0 of 50 of 27NCT00363168Trial comparisons
Dexamethasone and Ranibizumab vs Ranibizumab and Sham: serious adverse events0 of 20 of 24NCT01122511Trial comparisons

diseases-2026-09-18-0.1.0

Sources 6

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this list from software.

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/diseases/v1/MONDO_0810000/comparisons