Drug · CHEMBL1908359
SODIUM MONOFLUOROPHOSPHATE
7 sourcespipelines-2026-09-18-0.3.1
Cite this record
ConductScience Library. SODIUM MONOFLUOROPHOSPHATE. Drugs and targets, record CHEMBL1908359. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL1908359
On this page
Drug
Names and IDs as ChEMBL gives them, through Open Targets.
Targets0
The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.
None in this release.
Diseases6
The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.
| Disease | Open Targets' stage | Stage reported by | Reports | Of them trials | Its drugs |
|---|---|---|---|---|---|
| gingivitis | Approval | DailyMed | 11 | 8 | https://conductscience.org/library/drugs?q=MONDO_0002508 |
| dental caries | Approval | DailyMed | 22 | 6 | https://conductscience.org/library/drugs?q=MONDO_0005276 |
| allergic disease | Phase 2 | ClinicalTrials.gov | 1 | 1 | https://conductscience.org/library/drugs?q=MONDO_0005271 |
| dental fluorosis | Phase 1 | ClinicalTrials.gov | 1 | 1 | https://conductscience.org/library/drugs?q=MONDO_0006722 |
| periodontal disorder | Approval | DailyMed | 1 | 0 | https://conductscience.org/library/drugs?q=MONDO_0002635 |
| periodontitis | Approval | DailyMed | 1 | 0 | https://conductscience.org/library/drugs?q=MONDO_0005076 |
Source Open Targets
Trials30
Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs. 2 more that Open Targets linked to it are not shown, since the release's checks do not confirm them.
| Trial | Title | Phase | Participants | Results first posted | Named as | Linked by | Source |
|---|---|---|---|---|---|---|---|
| NCT01691560 | Exploratory Study to Evaluate an Occlusion Based Dentifrice in Relief of Dentinal Hypersensitivity | Phase 2 | 140 | 2014-05-29 | sodium monofluorophosphate | Its name | ClinicalTrials.gov |
| NCT01831817 | Exploratory Study to Evaluate the Efficacy of an Occlusion Based Dentifrice in Relief of Dentinal Hypersensitivity | Phase 2 | 140 | 2015-03-26 | sodium monofluorophosphate | Its name | ClinicalTrials.gov |
| NCT01592864 | The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity | Phase 3 | 120 | 2014-03-10 | sodium monofluorophosphate | Its name | ClinicalTrials.gov |
| NCT03072719 | The Efficacy of a Dentifrice in Providing Relief From Immediate and Short Term Relief From Dentinal Hypersensitivity | Phase 3 | 120 | 2017-04-18 | sodium monofluorophosphate | Its name | ClinicalTrials.gov |
| NCT03965039 | A Clinical Study to Assess the Effects of Various Dentifrice Technologies on Dentinal Hypersensitivity | 120 | 2020-10-30 | sodium monofluorophosphate | Its name | ClinicalTrials.gov | |
| NCT01827670 | Investigating the Efficacy of a Dentifrice in Providing Long Term Relief From Dentinal Hypersensitivity | Phase 3 | 119 | 2015-01-26 | sodium monofluorophosphate | Its name | ClinicalTrials.gov |
| NCT01592851 | Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity | Phase 3 | 113 | 2014-06-03 | sodium monofluorophosphate | Its name | ClinicalTrials.gov |
| NCT01657877 | Anti-caries Potential of a Sodium Monofluorophosphate and Calcium Sodium Phosphosilicate Dentifrice | Phase 2 | 100 | 2014-07-24 | sodium monofluorophosphate | Its name | ClinicalTrials.gov |
| NCT01128946 | Enamel Remineralization Potential of Dentifrices in Situ | Phase 4 | 83 | 2013-11-04 | sodium monofluorophosphate | Its name | ClinicalTrials.gov |
| NCT01005966 | In Situ Caries Model of Fluoride Toothpastes | Phase 3 | 65 | 2013-07-29 | sodium monofluorophosphate | Its name | ClinicalTrials.gov |
1 to 10 of 30
See all 30 trialsComparisons in its trials8
Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.
| Comparison | Group 1, with the outcome | Group 2, with the outcome | Participants | Trial | Source |
|---|---|---|---|---|---|
| Experimental Dentifrice vs Reference Dentifrice: deaths from any cause | 0 of 60 | 0 of 60 | 120 | NCT03072719 | Trial comparisons |
| Experimental Dentifrice vs Reference Dentifrice: serious adverse events | 0 of 60 | 0 of 60 | 120 | NCT03072719 | Trial comparisons |
| Test Dentifrice (0.454% Stannous Fluoride) vs Control Dentifrice (0.76% Sodium Monofluorophosphate): serious adverse events | 0 of 59 | 0 of 60 | 119 | NCT01827670 | Trial comparisons |
| SnF Dentifrice vs NaMFP Dentifrice: serious adverse events | 0 of 60 | 1 of 58 | 118 | NCT01592864 | Trial comparisons |
| SnF Dentifrice vs NaMFP Dentifrice: serious adverse events | 0 of 56 | 0 of 57 | 113 | NCT01592851 | Trial comparisons |
| Total Toothpaste vs Fluoride Toothpaste: serious adverse events | 0 of 24 | 0 of 25 | 49 | NCT00762528 | Trial comparisons |
| Total Toothpaste (Active) vs Colgate Cavity Protection (Placebo): serious adverse events | 0 of 24 | 0 of 25 | 49 | NCT00941668 | Trial comparisons |
| Fluoride vs Triclosan + Fluoride: serious adverse events | 0 of 18 | 0 of 17 | 35 | NCT00759031 | Trial comparisons |
Papers from its trials4
The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.
Tests in its trials0
The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.
None in this release.
Data dates
The date of each source this release read.
Sources 7
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ConductCognition's list of its testsOur own data
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this drug from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/drugs/v1/CHEMBL1908359
GET https://conductscience.org/api/drugs/v1/CHEMBL1908359/trials?page=2