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Drug · CHEMBL29

PENICILLIN G

7 sourcespipelines-2026-09-18-0.3.1

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ConductScience Library. PENICILLIN G. Drugs and targets, record CHEMBL29. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL29

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Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name
PENICILLIN G
ChEMBL
ChEMBL ID
CHEMBL29
ChEMBL
Type
Small molecule
ChEMBL
Brand names
Crystapen g
ChEMBL
Other names
Bencilpenicilina, Benzyl penicillin, Benzylpenicillin, Benzylpenicilline, J01CE01, NSC-193396
ChEMBL
Other form
PENICILLIN G BENZATHINE, CHEMBL3989515
Drugs and targets
Other form
PENICILLIN G POTASSIUM, CHEMBL1223
Drugs and targets
Other form
PENICILLIN G SODIUM, CHEMBL1126
Drugs and targets
DrugBank
DB01053
DrugBank
InChIKey
JGSARLDLIJGVTE-MBNYWOFBSA-N
ChEMBL
Open Targets' highest stage
Approval, for 2 of its 17 diseases, from ATC
Open Targets

Targets0

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

None in this release.

Diseases17

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DiseaseOpen Targets' stageStage reported byReportsOf them trialsIts drugs
syphilisPhase 3ClinicalTrials.gov44https://conductscience.org/library/drugs?q=MONDO_0005976
Neonatal sepsisUnknownClinicalTrials.gov11https://conductscience.org/library/drugs?q=HP_0040187
aspiration pneumoniaUnknownClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0000265
bacterial arthritisPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0004471
bacterial infectious disease with sepsisPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005229
congenital syphilisPhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005714
latent syphilisPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005822
neurosyphilisPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0004944
obsessive-compulsive disorderPhase 2ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0008114
osteomyelitisPhase 3ClinicalTrials.gov11https://conductscience.org/library/drugs?q=MONDO_0005246

Trials19

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs. 7 more rest on that reading alone and are shown because the trials' posted result groups or NLM's indexing of their papers name the drug. 10 more that Open Targets linked to it are not shown, since the release's checks do not confirm them.

TrialTitlePhaseParticipantsResults first postedNamed asLinked bySource
NCT03637660Phase 4 Comparative Trial of Benzathine Penicillin G for Treatment of Early Syphilis in Subjects With or Without HIV InfectionPhase 42492023-12-26benzathine penicillin GOpen Targets' reading, confirmed by the trial's result groups and NLM's indexing of its papersClinicalTrials.gov
NCT02611765Syphilis Response to Higher Penicillin Dosage: The 2.4 Versus 7.2 StudyPhase 4642016-04-11benzathine penicillin GOpen Targets' reading, confirmed by the trial's result groups and NLM's indexing of its papersClinicalTrials.gov
NCT03660488Cefixime for Alternative Syphilis TreatmentPhase 2582022-07-26benzathine penicillin gOpen Targets' reading, confirmed by the trial's result groupsClinicalTrials.gov
NCT03174236First Line Antimicrobials in Children With Complicated Severe Acute MalnutritionPhase 32,000benzyl penicillinIts nameClinicalTrials.gov
NCT05693545GOALIE: Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent RHD TrialPhase 21,004benzathine penicillin gOpen Targets' reading, confirmed by NLM's indexing of its papersClinicalTrials.gov
NCT03346525Determining the Impact of Penicillin in Latent RHD: The GOAL TrialPhase 2807benzathine penicillin GOpen Targets' reading, confirmed by NLM's indexing of its papersClinicalTrials.gov
NCT00031499Azithromycin/Bicillin SyphilisPhase 3593benzathine penicillin GOpen Targets' reading, confirmed by NLM's indexing of its papersClinicalTrials.gov
NCT01156740Treatment of Group A Beta Hemolytic Streptococcal Pharyngitis in Children in Low Resource Settings558penicillin gIts nameClinicalTrials.gov
NCT06726395Comparison of Cloxacillin and Benzylpenicillin in Penicillin Susceptible S. Aureus BacteraemiaPhase 4420benzylpenicillinIts nameClinicalTrials.gov
NCT04876131Single Dose Intravenous Antibiotics for Complicated Urinary Tract Infections in ChildrenPhase 4396benzylpenicillinIts nameClinicalTrials.gov

1 to 10 of 19

See all 19 trials

Comparisons in its trials0

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

None in this release.

Papers from its trials0

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

None in this release.

Tests in its trials0

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

None in this release.

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
ClinicalTrials.gov
2026-11-05
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
Papers the trials list, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
Tests named in the trials, as ScienceGraph matched them
2026-11-12
ConductCognition

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL29

GET https://conductscience.org/api/drugs/v1/CHEMBL29/targets