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Drug · CHEMBL32

MOXIFLOXACIN

7 sourcespipelines-2026-09-18-0.3.1

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ConductScience Library. MOXIFLOXACIN. Drugs and targets, record CHEMBL32. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL32

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Drug

Names and IDs as ChEMBL gives them, through Open Targets.

Name
MOXIFLOXACIN
ChEMBL
ChEMBL ID
CHEMBL32
ChEMBL
Type
Small molecule
ChEMBL
Brand names
Avelox, Avelox i.v.
ChEMBL
Other names
Avelox iv, Moxifloxacine, Moxifloxacino, Zimoxin
ChEMBL
Other form
MOXIFLOXACIN HYDROCHLORIDE, CHEMBL1200735
Drugs and targets
DrugBank
DB00218
DrugBank
InChIKey
FABPRXSRWADJSP-MEDUHNTESA-N
ChEMBL
Open Targets' highest stage
Approval, for 2 of its 53 diseases, from ATC and TTD
Open Targets

Targets0

The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.

None in this release.

Diseases53

The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.

DiseaseOpen Targets' stageStage reported byReportsOf them trialsIts drugs
pulmonary tuberculosisPhase 3ClinicalTrials.gov2828https://conductscience.org/library/drugs?q=MONDO_0006052
tuberculosisPhase 3ClinicalTrials.gov2626https://conductscience.org/library/drugs?q=MONDO_0018076
multidrug-resistant tuberculosisPhase 3ClinicalTrials.gov77https://conductscience.org/library/drugs?q=MONDO_0005861
Helicobacter pylori infectious diseasePhase 3ClinicalTrials.gov55https://conductscience.org/library/drugs?q=MONDO_0006781
bacterial conjunctivitisPhase 3ClinicalTrials.gov55https://conductscience.org/library/drugs?q=MONDO_0006668
chronic obstructive pulmonary diseasePhase 3ClinicalTrials.gov55https://conductscience.org/library/drugs?q=MONDO_0005002
appendicitisUnknownClinicalTrials.gov44https://conductscience.org/library/drugs?q=MONDO_0005649
breast cancerPhase 3ClinicalTrials.gov33https://conductscience.org/library/drugs?q=MONDO_0007254
endophthalmitisPhase 1/2ClinicalTrials.gov33https://conductscience.org/library/drugs?q=MONDO_0016047
fungal keratitisPhase 3ClinicalTrials.gov33https://conductscience.org/library/drugs?q=MONDO_0033821

Trials399

Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs.

TrialTitlePhaseParticipantsResults first postedNamed asLinked bySource
NCT02410772TBTC Study 31: Rifapentine-containing Tuberculosis Treatment Shortening RegimensPhase 32,5162021-09-28moxifloxacinIts nameClinicalTrials.gov
NCT00864383Controlled Comparison of Two Moxifloxacin Containing Treatment Shortening Regimens in Pulmonary TuberculosisPhase 31,9312015-05-25moxifloxacinIts nameClinicalTrials.gov
NCT02800785The Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) Trial1,5522023-04-18moxifloxacinIts nameClinicalTrials.gov
NCT00759148Moxifloxacin AF Ophthalmic Solution for Treatment of Bacterial ConjunctivitisPhase 31,1792011-03-22moxifloxacinIts nameClinicalTrials.gov
NCT00348348A Study to Investigate the Safety and Efficacy of BOL-303224 in the Treatment of Bacterial ConjunctivitisPhase 31,1612009-08-13moxifloxacinIts nameClinicalTrials.gov
NCT01573910An Evaluation of the Safety and Efficacy of Moxifloxacin Ophthalmic Solution 0.5% ((VIGAMOX®) Versus Ofloxacin Ophthalmic Solution 0.3% in the Treatment of Bacterial Conjunctivitis in Chinese PatientsPhase 39852015-05-12moxifloxacinIts nameClinicalTrials.gov
NCT00402727Comparison of Sequential IV/PO Moxifloxacin With IV Piperacillin/Tazobactam Followed by PO Amoxicillin/Clavulanic Acid in Patients With a Complicated Skin and Skin Structure InfectionPhase 38132010-01-11moxifloxacinIts nameClinicalTrials.gov
NCT00492726Therapy of Complicated Intra-Abdominal Infections With Moxifloxacin or ErtapenemPhase 38042010-03-03moxifloxacinIts nameClinicalTrials.gov
NCT02813694Study to Compare Lefamulin to Moxifloxacin for the Treatment of Adults With PneumoniaPhase 37382019-10-23moxifloxacinIts nameClinicalTrials.gov
NCT02409290The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TBPhase 35882023-09-28moxifloxacinIts nameClinicalTrials.gov

1 to 10 of 399

See all 399 trials

Comparisons in its trials71

Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.

ComparisonGroup 1, with the outcomeGroup 2, with the outcomeParticipantsTrialSource
Antibiotics Therapy Arm vs Appendectomy Arm: Rates of Participants With Appendiceal Cancer4 of 7766 of 7761,552NCT02800785Trial comparisons
Antibiotics Therapy Arm vs Appendectomy Arm: Total Number of Patients Who Had Resolution of Appendicitis Symptoms at 30 Days462 of 676466 of 6631,339NCT02800785Trial comparisons
Antibiotics Therapy Arm vs Appendectomy Arm: Number of Participants With at Least One Complications From Treatment37 of 67621 of 6561,332NCT02800785Trial comparisons
Antibiotics Therapy Arm vs Appendectomy Arm: deaths from any cause0 of 6760 of 6561,332NCT02800785Trial comparisons
Antibiotics Therapy Arm vs Appendectomy Arm: serious adverse events19 of 67619 of 6561,332NCT02800785Trial comparisons
Moxifloxacin AF vs Vehicle: deaths from any cause0 of 5930 of 5861,179NCT00759148Trial comparisons
Moxifloxacin AF vs Vehicle: serious adverse events0 of 5930 of 5861,179NCT00759148Trial comparisons
Moxifloxacin Solution vs Besifloxacin Suspension: serious adverse events1 of 5791 of 5821,161NCT00348348Trial comparisons
Moxifloxacin vs Ofloxacin: serious adverse events1 of 4890 of 493982NCT01573910Trial comparisons
Antibiotics Therapy Arm vs Appendectomy Arm: Rate of Participants With Perforated Appendicitis59 of 18599 of 621806NCT02800785Trial comparisons

Papers from its trials376

The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.

PMIDListed asTrials listing itSource
40645198RESULT1PubMed
40360262RESULT1PubMed
40261382RESULT1PubMed
39279639RESULT1PubMed
38768617RESULT2PubMed
37980911RESULT2PubMed
37888913RESULT1PubMed
37877585RESULT1PubMed
37567554RESULT1PubMed
37256341RESULT1PubMed

Tests in its trials0

The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.

None in this release.

Data dates

The date of each source this release read.

Open Targets
2026-09-18
Open Targets
ClinicalTrials.gov
2026-11-05
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
Papers the trials list, from Trials
2026-11-12
Trials
Comparisons, from Trial comparisons
2026-03-23
Trial comparisons
Tests named in the trials, as ScienceGraph matched them
2026-11-12
ConductCognition

Sources 7

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ConductCognition's list of its testsOur own data
  • ClinicalTrials.govNo license stated
  • NLM's MeSHNLM's terms
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
  • ClinicalTrials.govnone stated
  • NLM's MeSHNLM's
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this drug from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/drugs/v1/CHEMBL32

GET https://conductscience.org/api/drugs/v1/CHEMBL32/diseases?page=2