Drug · CHEMBL8
CIPROFLOXACIN
7 sourcespipelines-2026-09-18-0.3.1
Cite this record
ConductScience Library. CIPROFLOXACIN. Drugs and targets, record CHEMBL8. Release pipelines-2026-09-18-0.3.1, 18 Sept 2026. https://conductscience.org/library/drugs/CHEMBL8
On this page
Drug
Names and IDs as ChEMBL gives them, through Open Targets.
- Other names
- BAY O 9867 FREE BASE, BAY Q 3939, BAY-O-9867 FREE BASE, BAY-Q-3939, BAYQ3939, Ciprofloxacine, Ciprofloxacino, Ciprofloxacinum, NSC-758467
- ChEMBL
- Open Targets' highest stage
- Approval, for 14 of its 71 diseases, from ATC, DailyMed and TTD
- Open Targets
Targets0
The targets ChEMBL's mechanism records give for the drug, through Open Targets. A mechanism record says what the drug acts on, not how strongly.
None in this release.
Diseases71
The diseases Open Targets' clinical reports study the drug for, the most trial reports first. The stage is Open Targets', the highest any of its sources reports for the pair, and each row names the sources that report it.
1 to 10 of 71Source Open Targets
See all 71 diseasesTrials270
Trials whose record names the drug by a name ChEMBL states, posted results first, then the largest. Open Targets read each trial's text to find its drugs. 1 more rests on that reading alone and is shown because the trial's posted result groups or NLM's indexing of its papers name the drug. 4 more that Open Targets linked to it are not shown, since the release's checks do not confirm them.
| Trial | Title | Phase | Participants | Results first posted | Named as | Linked by | Source |
|---|---|---|---|---|---|---|---|
| NCT03354598 | Oral Sulopenem-etzadroxil/Probenecid Versus Ciprofloxacin for Uncomplicated Urinary Tract Infection in Adult Women | Phase 3 | 1,671 | 2020-12-17 | ciprofloxacin | Its name | ClinicalTrials.gov |
| NCT02800785 | The Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) Trial | 1,552 | 2023-04-18 | ciprofloxacin | Its name | ClinicalTrials.gov | |
| NCT00761462 | BAY 0 9867 Cipro Pediatric Use Study (QUIP) | Phase 3 | 1,029 | 2009-04-14 | ciprofloxacin | Its name | ClinicalTrials.gov |
| NCT01208922 | Rifamycin SV-MMX® Tablets Versus Ciprofloxacin Capsules in Acute Traveller's Diarrhoea | Phase 3 | 835 | 2019-02-27 | ciprofloxacin | Its name | ClinicalTrials.gov |
| NCT01659866 | Antibiotic Prophylaxis for Transrectal Prostate Biopsy | Phase 4 | 563 | 2019-06-25 | ciprofloxacin | Its name | ClinicalTrials.gov |
| NCT02106832 | Ciprofloxacin Dry Powder for Inhalation (DPI) in Non-cystic Fibrosis Bronchiectasis (Non-CF BE) | Phase 3 | 521 | 2017-09-01 | ciprofloxacin | Its name | ClinicalTrials.gov |
| NCT02600559 | Open-Label Study of OTO-201 in Pediatric Subjects With a History of Otitis Media Requiring Tympanostomy Tubes | Phase 3 | 501 | 2020-09-22 | ciprofloxacin | Its name | ClinicalTrials.gov |
| NCT02216071 | Comparative Efficacy and Safety of Ciprofloxacin 0.3% and Dexamethasone 0.1% in Acute Otitis Externa | Phase 3 | 499 | 2021-05-28 | ciprofloxacin | Its name | ClinicalTrials.gov |
| NCT03196973 | Efficacy and Safety of DF289 Plus DF277 Otic Solution in the Treatment of Acute Otitis Externa | Phase 3 | 493 | 2021-04-09 | ciprofloxacin | Its name | ClinicalTrials.gov |
| NCT01764841 | Ciprofloxacin Dry Powder for Inhalation in Non-cystic Fibrosis Bronchiectasis (Non-CF BE) | Phase 3 | 416 | 2017-05-24 | ciprofloxacin | Its name | ClinicalTrials.gov |
1 to 10 of 270
See all 270 trialsComparisons in its trials116
Comparisons Trial comparisons calculated in the trials whose record names the drug, most participants first. A comparison in one of its trials does not always compare the drug, so read the two groups.
| Comparison | Group 1, with the outcome | Group 2, with the outcome | Participants | Trial | Source |
|---|---|---|---|---|---|
| Sulopenem-etzadroxil/Probenecid vs Ciprofloxacin: deaths from any cause | 1 of 833 | 0 of 827 | 1,660 | NCT03354598 | Trial comparisons |
| Sulopenem-etzadroxil/Probenecid vs Ciprofloxacin: serious adverse events | 6 of 833 | 2 of 827 | 1,660 | NCT03354598 | Trial comparisons |
| Antibiotics Therapy Arm vs Appendectomy Arm: Rates of Participants With Appendiceal Cancer | 4 of 776 | 6 of 776 | 1,552 | NCT02800785 | Trial comparisons |
| Antibiotics Therapy Arm vs Appendectomy Arm: Total Number of Patients Who Had Resolution of Appendicitis Symptoms at 30 Days | 462 of 676 | 466 of 663 | 1,339 | NCT02800785 | Trial comparisons |
| Antibiotics Therapy Arm vs Appendectomy Arm: Number of Participants With at Least One Complications From Treatment | 37 of 676 | 21 of 656 | 1,332 | NCT02800785 | Trial comparisons |
| Antibiotics Therapy Arm vs Appendectomy Arm: deaths from any cause | 0 of 676 | 0 of 656 | 1,332 | NCT02800785 | Trial comparisons |
| Antibiotics Therapy Arm vs Appendectomy Arm: serious adverse events | 19 of 676 | 19 of 656 | 1,332 | NCT02800785 | Trial comparisons |
| Ciprofloxacin vs Non-quinolone Antibiotic: serious adverse events | 25 of 487 | 6 of 507 | 994 | NCT00761462 | Trial comparisons |
| Group A vs Group B: Number of Patients With Clinical Cure | 357 of 420 | 352 of 415 | 835 | NCT01208922 | Trial comparisons |
| Group A vs Group B: deaths from any cause | 0 of 420 | 0 of 415 | 835 | NCT01208922 | Trial comparisons |
1 to 10 of 116
See all 116 comparisons in its trialsPapers from its trials140
The papers the trials whose record names the drug list on ClinicalTrials.gov as their results (RESULT) or as drawn from them (DERIVED), results first, newest first.
Tests in its trials0
The tests ConductCognition runs that the trials whose record names the drug name in their registered outcomes, as ScienceGraph matched them. ConductCognition's list names the tests it runs, not every test a trial used.
None in this release.
Data dates
The date of each source this release read.
Sources 7
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ConductCognition's list of its testsOur own data
- ClinicalTrials.govNo license stated
- NLM's MeSHNLM's terms
- Open TargetsCC0 1.0
- PubMedNLM's terms
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ConductCognition's list of its testsOur own data: ConductCognition's list of its tests, https://conductcognition.com
- ClinicalTrials.govnone stated
- NLM's MeSHNLM's
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this drug from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/drugs/v1/CHEMBL8
GET https://conductscience.org/api/drugs/v1/CHEMBL8/diseases?page=2