Gene · 1583
CYP11A1: cytochrome P450 family 11 subfamily A member 1
11 sourcesgene-search-2026-11-11-0.1.0
Cite this record
ConductScience Library. CYP11A1: cytochrome P450 family 11 subfamily A member 1. Genes, record 1583. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/1583
On this page
Gene
Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P05108 | Cholesterol side-chain cleavage enzyme, mitochondrial | 521 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents16
Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026082924 A | 2026-05-19 | 4 | P05108 | Espacenet |
| US 12545918 B2 | 2026-02-10 | 6 | P05108 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2221 | P05108 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 2221 | P05108 | Espacenet |
| JP 2023515302 A | 2023-04-13 | 5 | P05108 | Espacenet |
| US 11612619 B2 | 2023-03-28 | 6 | P05108 | Espacenet |
| KR 1020220169238 A | 2022-12-27 | 2 | P05108 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 21889 | P05108 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 124860 | P05108 | Espacenet |
| JP 2021175409 A | 2021-11-04 | 63 | P05108 | Espacenet |
1 to 10 of 16
See all 16 patentsDrugs3
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials20
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT06831175 | MITOTANE | PHASE2 | ClinicalTrials.gov | |
| NCT05913427 | MITOTANE | PHASE2 | ClinicalTrials.gov | |
| NCT05634577 | MITOTANE | PHASE2 | 2025-06-19 | ClinicalTrials.gov |
| NCT05344027 | MITOTANE | ClinicalTrials.gov | ||
| NCT03723941 | MITOTANE | PHASE3 | ClinicalTrials.gov | |
| NCT03621280 | LEVOKETOCONAZOLE | PHASE3 | 2025-06-19 | ClinicalTrials.gov |
| NCT03583710 | MITOTANE | PHASE3 | ClinicalTrials.gov | |
| NCT03277690 | LEVOKETOCONAZOLE | PHASE3 | 2022-11-08 | ClinicalTrials.gov |
| NCT02057237 | MITOTANE | PHASE1 | 2015-12-17 | ClinicalTrials.gov |
| NCT01838551 | LEVOKETOCONAZOLE | PHASE3 | 2021-04-19 | ClinicalTrials.gov |
1 to 10 of 20
See all 20 trialsNIH grants1,708
NIH projects whose papers are about the gene, through NIH's grant-paper links.
| Project | Title | Its papers about the gene | Newest fiscal year |
|---|---|---|---|
| R01AR073004 | Mechanism of action and function of novel secosteroid 20(OH)D3 in the skin | 41 | 2025 |
| I01BX004293 | CYP11A1-derived secosteroids as therapeutic agents in UVB induced skin cancer | 33 | 2025 |
| R01DK043140 | Mechanisms Leading to Adrenal Zonation | 26 | 2025 |
| R01GM086596 | Activation of androgen biosynthesis and drug metabolism by cytochrome b5 | 16 | 2025 |
| P50CA097186 | The Pacific Northwest Prostate Cancer SPORE | 13 | 2025 |
| ZIAES101586 | Nuclear receptors: action, functions, and roles in disease | 13 | 2025 |
| T32ES007326 | Interdisciplinary Research Training Program in Environmental Health and Toxicology | 12 | 2025 |
| P30ES013508 | Center of Excellence in Environmental Toxicology | 11 | 2025 |
| P01CA163227 | Androgen Receptor Action in Castration Resistant Prostate Cancer | 7 | 2025 |
| P30CA013148 | Comprehensive Cancer Center Support Grant | 7 | 2025 |
1 to 10 of 1,708Source NIH's project files
See all 1,708 nih grantsPapers4,318
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| PMID | Found by | Source |
|---|---|---|
| 42813264 | PubTator, text mining | PubMed |
| 42794732 | PubTator, text mining | PubMed |
| 42792964 | PubTator, text mining | PubMed |
| 42777289 | PubTator, text mining | PubMed |
| 42772605 | PubTator, text mining | PubMed |
| 42737821 | PubTator, text mining | PubMed |
| 42737662 | PubTator, text mining | PubMed |
| 42721119 | PubTator, text mining | PubMed |
| 42710202 | PubTator, text mining | PubMed |
| 42644839 | PubTator, text mining | PubMed |
1 to 10 of 4,318
See all 4,318 papersSources 11
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNone stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GeneNone named. Public domain as US government information
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/1583
GET https://conductscience.org/api/genes/v1/1583/patents