Gene · 2166
FAAH: fatty acid amide hydrolase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. FAAH: fatty acid amide hydrolase. Genes, record 2166. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/2166
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O00519 | Fatty-acid amide hydrolase 1 | 579 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents34
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 45922 | O00519 | Espacenet |
| JP 2025536211 A | 2025-11-05 | 3 | O00519 | Espacenet |
| JP 2025535021 A | 2025-10-22 | 5 | O00519 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 1471 | O00519 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 1471 | O00519 | Espacenet |
| US 12241066 B2 | 2025-03-04 | 40 | O00519 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 30851 | O00519 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 2375 | O00519 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 133822 | O00519 | Espacenet |
| JP 2021512929 A | 2021-05-20 | 40 | O00519 | Espacenet |
1 to 10 of 34
See all 34 patentsDrugs3
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials299
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT07546370 | ACETAMINOPHEN | PHASE4 | ClinicalTrials.gov | |
| NCT07533487 | ACETAMINOPHEN | ClinicalTrials.gov | ||
| NCT07463482 | ACETAMINOPHEN | ClinicalTrials.gov | ||
| NCT07440446 | ACETAMINOPHEN | ClinicalTrials.gov | ||
| NCT07435493 | ACETAMINOPHEN | ClinicalTrials.gov | ||
| NCT07353372 | ACETAMINOPHEN | ClinicalTrials.gov | ||
| NCT07154433 | ACETAMINOPHEN | ClinicalTrials.gov | ||
| NCT06994442 | ACETAMINOPHEN | PHASE3 | ClinicalTrials.gov | |
| NCT06923540 | ACETAMINOPHEN | PHASE4 | ClinicalTrials.gov | |
| NCT06917118 | ACETAMINOPHEN | ClinicalTrials.gov |
1 to 10 of 299
See all 299 trialsNIH grants2,032
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | FAAH papers | Newest fiscal year |
|---|---|---|---|
| P01DA009158 | Endocannabinoid Active Sites as Therapeutic Targets | 28 | 2025 |
| P60AA006420 | CNS Effects of Alcohol: Cellular Neurobiology | 13 | 2025 |
| ZIAAA000375 | Mechanism of oxidative/nitrosative stress and inflammation-induced tissue injury | 12 | 2025 |
| ZIAAA000301 | Integrative genetics of behavior with high throughput technologies | 9 | 2025 |
| R37DA015648 | Modulating Signaling Endocannabinoids and Fatty Acid Amides | 8 | 2025 |
| T32DA007027 | Training in the pharmacology of abused drugs | 8 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 8 | 2025 |
| ZIAAA000411 | Mouse models of stress disorders and addiction | 8 | 2025 |
| ZIAAA000351 | Endocannabinoids and the Control Of Behavior and Cardiovascular Function | 7 | 2025 |
| R35ES030443 | Bioactive lipids as effectors and indicators of the deleterious effects of environmental exposure on chronic diseases | 6 | 2025 |
1 to 10 of 2,032Source NIH's project files
See all 2,032 nih grantsPapers3,784
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Structural optimization of donepezil-like hybrids toward an improved multi-target and ADME-related profile. | Bioorg Chem | 2026 | 42826663 | PubTator, text mining | PubMed |
| Tryptamide (nicotredole) revisited: re-examining a forgotten anti-inflammatory agent by large-scale target profiling and ADMET studies. | Pharmacol Rep | 2026 | 42811266 | PubTator, text mining | PubMed |
| In Vivo Characterization of Fatty Acid Amide Hydrolase in Posttraumatic Stress Disorder: A [11C]CURB Positron Emission Tomography Study. | Biol Psychiatry | 2026 | 42772587 | PubTator, text mining | PubMed |
| Tai Chi exercise of short duration alters circulating oxylipins in postmenopausal women: a pilot study. | Front Med (Lausanne) | 2026 | 42740961 | PubTator, text mining | PubMed |
| N-Arachidonoyl-phosphatidylethanolamide phospholipase D activation by muscarinic receptors. | J Physiol | 2026 | 42687141 | PubTator, text mining | PubMed |
| Fatty acid amide hydrolase (FAAH) inhibitor design and preclinical studies: lessons learned from BIA 10-2474 and the challenges ahead. | Expert Opin Drug Discov | 2026 | 42615850 | PubTator, text mining | PubMed |
| Mechanistic Insights into the Analgesic Action of Acetaminophen: Its Bioactive Metabolite Induces Peripheral Analgesia in Addition to Central Analgesia. | Med Princ Pract | 2026 | 42607026 | PubTator, text mining | PubMed |
| Exercise-induced anandamide-CB1R signaling and prefrontal-amygdala stress circuits in adolescent depression: a critical hypothesis-driven narrative review. | Front Psychiatry | 2026 | 42602360 | PubTator, text mining | PubMed |
| Resmetirom Ameliorates Fibrogenesis in Hepatic Stellate Cells via Thyroid Hormone Receptor Alpha-Fatty-Acid Amide Hydrolase 1 Signaling Pathway. | MedComm (2020) | 2026 | 42558980 | PubTator, text mining | PubMed |
| Quantification of [11C]CURB PET using an irreversible reference tissue model with a cluster-derived pseudo-reference region. | Front Neurosci | 2026 | 42548758 | PubTator, text mining | PubMed |
1 to 10 of 3,784
See all 3,784 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/2166
GET https://conductscience.org/api/genes/v1/2166/patents?page=2