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Gene · 55867

SLC22A11: solute carrier family 22 member 11

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. SLC22A11: solute carrier family 22 member 11. Genes, record 55867. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/55867

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Gene

Symbol
SLC22A11
HGNC
Name
solute carrier family 22 member 11
HGNC
NCBI Gene ID
55867
NCBI Gene
HGNC ID
HGNC:18120
HGNC
Ensembl
ENSG00000168065
NCBI Gene
Aliases
OAT4, hOAT4
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9NSA0Solute carrier family 22 member 115503Ensembl, GeneID, HGNC

Source UniProt

Patents26

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1464180Q9NSA0Espacenet
JP 2025529142 A2025-09-044050Q9NSA0Espacenet
US 12371689 B22025-07-294050Q9NSA0Espacenet
US 11446398 B22022-09-2080760Q9NSA0Espacenet
US 11400116 B22022-08-024460Q9NSA0Espacenet
JP 2022524081 A2022-04-27183731Q9NSA0Espacenet
US 11078247 B22021-08-0310384Q9NSA0Espacenet
WO 2019183292 A12019-09-2618Q9NSA0Espacenet
JP 2019054813 A2019-04-11244615Q9NSA0Espacenet
JP 2017121241 A2017-07-13244615Q9NSA0Espacenet

1 to 10 of 26

See all 26 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
PROBENECIDCHEMBL897Solute carrier family 22 member 11 inhibitorINHIBITOR

Source ChEMBL

Trials16

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07118618PROBENECIDPHASE2ClinicalTrials.gov
NCT07092813PROBENECIDPHASE1ClinicalTrials.gov
NCT05903859PROBENECIDPHASE3ClinicalTrials.gov
NCT05442983PROBENECIDPHASE2ClinicalTrials.gov
NCT04551222PROBENECIDPHASE2/PHASE3ClinicalTrials.gov
NCT04218357PROBENECIDPHASE12025-02-27ClinicalTrials.gov
NCT03357614PROBENECIDPHASE32020-12-29ClinicalTrials.gov
NCT02243631PROBENECIDEARLY_PHASE12022-07-26ClinicalTrials.gov
NCT01816646PROBENECIDPHASE1ClinicalTrials.gov
NCT01320722PROBENECIDPHASE32017-06-29ClinicalTrials.gov

1 to 10 of 16

See all 16 trials

NIH grants544

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleSLC22A11 papersNewest fiscal year
R01DK109392The Role in OAT1 in Uremia82025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal82025
P30ES005022Rutgers Center for Environmental Exposure and Disease (CEED)62025
P30ES007033University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment52025
T32ES007148Training in Environmental Toxicology52025
P30ES006694Southwest Environmental Health Sciences Center42025
R01AI077505Pharmacogenomics of HIV Therapy42025
P30DK056350Nutrition Obesity Research Center (NORC)32025
P30AI050410The University of North Carolina Center for AIDS Research22025
P30CA021765Cancer Center Support Grant (CCSG)22025

1 to 10 of 544Source NIH's project files

See all 544 nih grants

Papers695

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Associations of Genetic Variants in Uric Acid Transporter Genes With Salt Sensitivity, Longitudinal Blood Pressure Changes, and Incident Hypertension in Chinese Adults.J Clin Hypertens (Greenwich)202642745169PubTator, text miningPubMed
Comparison of the permeability of RdRp inhibitors, remdesivir, molnupiravir and azvudine, in placental barrier cell models and exploration of their transport mechanisms.J Antimicrob Chemother202642497385PubTator, text miningPubMed
Comparison of the permeability of DPP-4 inhibitors-sitagliptin, vildagliptin, linagliptin, and alogliptin-in placental barrier cell models and exploration of their transport mechanisms by LC-MS/MS.BMC Pregnancy Childbirth202642443801PubTator, text miningPubMed
Urine-to-Blood Partitioning of Per- and Polyfluoroalkyl Substances in Human Biomonitoring: Implications for Environmental Exposure Analysis and Bioaccumulation Assessment.Molecules202642280183PubTator, text miningPubMed
Regulation of Human Renal Transporters by Pregnancy-Related Hormones in Primary Proximal Tubular Epithelial Cells.Metabolites202642188001PubTator, text miningPubMed
Functional characterization of human organic anion transporter 4 (hOAT4) as a pH-dependent citrate transporter in renal proximal tubules.J Pharmacol Sci202641866670PubTator, text miningPubMed
Integrated Transcriptomic and Histological Analysis of TP53/CTNNB1 Mutations and Microvascular Invasion in Hepatocellular Carcinoma.Genes (Basel)202641751574PubTator, text miningPubMed
Dicloxacillin and Flucloxacillin Inhibit Hepatic Uptake Transporters-In Vitro Investigations and Physiologically Based Pharmacokinetic Modeling.Clin Transl Sci202641630535PubTator, text miningPubMed
Expression of drug transporters in human allogenic transplanted kidneys in acute rejection.Toxicol Appl Pharmacol202641581572PubTator, text miningPubMed
Inhibition of human organic anion transporter 4 (OAT4) activity by bisphenol analogues.Environ Pollut202641407188PubTator, text miningPubMed

1 to 10 of 695

See all 695 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/55867

GET https://conductscience.org/api/genes/v1/55867/patents?page=2