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Gene · 886

CCKAR: cholecystokinin A receptor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CCKAR: cholecystokinin A receptor. Genes, record 886. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/886

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Gene

Symbol
CCKAR
HGNC
Name
cholecystokinin A receptor
HGNC
NCBI Gene ID
886
NCBI Gene
HGNC ID
HGNC:1570
HGNC
Ensembl
ENSG00000163394
NCBI Gene
Aliases
CCK-1R, CCK-A, CCK-AR, CCK1-R, CCK1R, CCKRA
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P32238Cholecystokinin receptor type A42814Ensembl, GeneID, HGNC

Source UniProt

Patents33

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1441193P32238Espacenet
JP 2025529142 A2025-09-04754P32238Espacenet
US 12371689 B22025-07-29754P32238Espacenet
US 11446398 B22022-09-2014980P32238Espacenet
US 11400116 B22022-08-02216P32238Espacenet
JP 2022524081 A2022-04-27117951P32238Espacenet
US 11078247 B22021-08-031712P32238Espacenet
US 10772934 B22020-09-15990P32238Espacenet
US 10292374 B22019-05-21316P32238Espacenet
JP 2019054813 A2019-04-11221628P32238Espacenet

1 to 10 of 33

See all 33 patents

Drugs6

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
CE-326597CHEMBL1269258Cholecystokinin A receptor agonistAGONISTChEMBL
CERULETIDECHEMBL1201355Cholecystokinin A receptor agonistAGONISTChEMBL
CERULETIDE DIETHYLAMINECHEMBL1200755Cholecystokinin A receptor agonistAGONISTChEMBL
DEXLOXIGLUMIDECHEMBL550781Cholecystokinin A receptor antagonistANTAGONISTChEMBL
PROGLUMIDECHEMBL316561Cholecystokinin receptor antagonistANTAGONISTChEMBL
SINCALIDECHEMBL1121Cholecystokinin A receptor agonistAGONISTChEMBL

Trials6

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06017323PROGLUMIDEPHASE1ClinicalTrials.gov
NCT05827055PROGLUMIDEPHASE2ClinicalTrials.gov
NCT05551858PROGLUMIDEPHASE1/PHASE2ClinicalTrials.gov
NCT04152473PROGLUMIDEPHASE1ClinicalTrials.gov
NCT00542009CE-326597PHASE2ClinicalTrials.gov
NCT00220090DEXLOXIGLUMIDEPHASE3ClinicalTrials.gov

NIH grants613

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCCKAR papersNewest fiscal year
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant72025
P30CA056036Translational Research in Cancer52025
ZIADK053100Characterization And Pharmacology Of Receptors For Gastrointestinal Peptides52025
T32GM008562Clinical Pharmacology Training Program42025
ZIADK053101Cellular Basis Of Action Of Gastrointestinal Peptides/Growth factors42025
R01DA036596Regulation of Neuronal GPCR Signaling32025
P30DK017047Diabetes Research Center22025
P30DK084567Mayo Center for Cell Signaling in Gastroenterology22025
P60AA006420CNS Effects of Alcohol: Cellular Neurobiology22025
R01GM129325ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale Modeling22025

1 to 10 of 613Source NIH's project files

See all 613 nih grants

Papers1,123

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrative network pharmacology, transcriptomics, and molecular docking identify candidate Centella asiatica constituents and targets in neurodegenerative diseases.PLoS One202642536688PubTator, text miningPubMed
Heart-Specific Spinal and Vagal Afferents: Transcriptomic Signatures and Optogenetically Modulated Functional Coupling With Cardiomyocytes.Compr Physiol202642381253PubTator, text miningPubMed
Molecular Characterization of Small Extracellular Vesicles in Pancreatic Cancer Patients Treated with Neoadjuvant Chemotherapy Followed by Stereotactic Body Radiation.Cancers (Basel)202642279288PubTator, text miningPubMed
Nmur1 and Cckar fail to support functional genetic access in adult dopamine neurons and challenge GPCR atlas assignments.bioRxiv202642182265PubTator, text miningPubMed
Peripheral cholecystokinin promotes thermogenesis via vagal afferent signalling, hypothalamic oxytocin and sympathetic outflow to brown adipose tissue.J Physiol202642120179PubTator, text miningPubMed
Cholecystokinin A Receptor Knockdown Diminishes Colon Cancer Cell Invasive Potential via Modulation of Integrin/FAK, EMT, and uPA/uPAR/MMP2 Axis.Oncol Res202641930160PubTator, text miningPubMed
Glucose Intake during the Neonatal Period Modulates the Central Melanocortin System with Breed-Specific Differences.J Poult Sci202641799539PubTator, text miningPubMed
Exploring the Pain-Relieving Potential: Unveiling Antinociceptive Properties in Animal Venoms and Toxins.Toxins (Basel)202641745735PubTator, text miningPubMed
Personalized Treatments for Functional Disorders of the Sphincter of Oddi: A Short Muscle with a Long History of Discussion and Controversies.J Pers Med202641745397PubTator, text miningPubMed
Comparison of receptor expression and cholecystokinin signaling between left and right nodose ganglia.Am J Physiol Cell Physiol202641661036PubTator, text miningPubMed

1 to 10 of 1,123

See all 1,123 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/886

GET https://conductscience.org/api/genes/v1/886/patents?page=2