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Gene · 887

CCKBR: cholecystokinin B receptor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CCKBR: cholecystokinin B receptor. Genes, record 887. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/887

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Gene

Symbol
CCKBR
HGNC
Name
cholecystokinin B receptor
HGNC
NCBI Gene ID
887
NCBI Gene
HGNC ID
HGNC:1571
HGNC
Ensembl
ENSG00000110148
NCBI Gene
Aliases
CCK-2R, CCK-B, CCK-BR, CCK2R, GASR
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P32239Gastrin/cholecystokinin type B receptor4475Ensembl, GeneID, HGNC

Source UniProt

Patents52

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1441194P32239Espacenet
EP 4641201 A22025-10-295940P32239Espacenet
JP 2025529142 A2025-09-04755P32239Espacenet
US 12371689 B22025-07-29755P32239Espacenet
JP 2025517969 A2025-06-125940P32239Espacenet
JP 2025032204 A2025-03-1125956P32239Espacenet
EP 4487869 A22025-01-08203P32239Espacenet
EP 4461818 A22024-11-1325956P32239Espacenet
KR 1020240027895 A2024-03-04395P32239Espacenet
JP 2023058610 A2023-04-2525956P32239Espacenet

1 to 10 of 52

See all 52 patents

Drugs4

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
CI-988CHEMBL2062154Cholecystokinin B receptor antagonistANTAGONISTChEMBL
ITRIGLUMIDECHEMBL1256717Cholecystokinin B receptor antagonistANTAGONISTChEMBL
NETAZEPIDECHEMBL324547Cholecystokinin B receptor antagonistANTAGONISTChEMBL
PROGLUMIDECHEMBL316561Cholecystokinin receptor antagonistANTAGONISTChEMBL

Trials9

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06017323PROGLUMIDEPHASE1ClinicalTrials.gov
NCT05827055PROGLUMIDEPHASE2ClinicalTrials.gov
NCT05551858PROGLUMIDEPHASE1/PHASE2ClinicalTrials.gov
NCT04152473PROGLUMIDEPHASE1ClinicalTrials.gov
NCT02620696NETAZEPIDEPHASE1ClinicalTrials.gov
NCT02597712NETAZEPIDEPHASE22021-04-12ClinicalTrials.gov
NCT01444014NETAZEPIDEPHASE2ClinicalTrials.gov
NCT01339169NETAZEPIDEPHASE2ClinicalTrials.gov
NCT01298999NETAZEPIDEPHASE22021-11-23ClinicalTrials.gov

NIH grants1,011

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCCKBR papersNewest fiscal year
P30CA051008Georgetown University Lombardi Comprehensive Cancer Center Support Grant102025
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant52025
T32GM008562Clinical Pharmacology Training Program52025
ZIADK053100Characterization And Pharmacology Of Receptors For Gastrointestinal Peptides52025
ZIADK053101Cellular Basis Of Action Of Gastrointestinal Peptides/Growth factors52025
P30CA013696Cancer Center Support Grant42025
P30CA056036Translational Research in Cancer42025
P30CA076292Moffitt Cancer Center Support Grant42025
P30DK020572Michigan Diabetes Research Center (MDRC)42025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202832025

1 to 10 of 1,011Source NIH's project files

See all 1,011 nih grants

Papers2,046

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Autoimmune gastritis diverges from a shared corpus origin: molecular reconstruction of the adenocarcinoma axis and clinical anchoring of the neuroendocrine axis.Front Immunol202642712509PubTator, text miningPubMed
Novel nastorazepide-based radioligands demonstrate effective cholecystokinin-2 receptor targeting with potential for theranostic applications.Theranostics202642707991PubTator, text miningPubMed
Targeted radionuclide-drug conjugates: Current status and perspectives.Eur J Med Chem202642520735PubTator, text miningPubMed
Therapeutic potential of pachymic acid in glioma: a comprehensive approach combining experimental validation, network pharmacology, and machine learning.Brain Res202642468874PubTator, text miningPubMed
Immune and clinicopathological features of molecularly defined prolactinoma subtypes.J Neurosurg202642361377PubTator, text miningPubMed
Development of Novel Cholecystokinin 2 Receptor-Targeted Radioligand Containing Albumin Binder for Efficient 111In/177Lu Theranostics.Bioconjug Chem202642283376PubTator, text miningPubMed
Effects of Lacticaseibacillus paracasei HP7 Against Helicobacter pylori-Induced Gastric Mucosal Inflammation and Mucosal Protection.J Med Food202641870161PubTator, text miningPubMed
A progressive fine-tuning framework with dynamic parameter selection for low-resource peptide-GPCR interaction prediction.Brief Bioinform202641838876PubTator, text miningPubMed
Integrated network toxicology and computational profiling of acetyl tributyl citrate-related mechanisms in Alzheimer's disease.J Alzheimers Dis202641823681PubTator, text miningPubMed
Gastrin ameliorates heart failure and suppresses myocardial remodeling via the JAK2/STAT3 and ERK1/2 pathways.PLoS One202641785239PubTator, text miningPubMed

1 to 10 of 2,046

See all 2,046 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/887

GET https://conductscience.org/api/genes/v1/887/patents?page=2