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Gene · 9340

GLP2R: glucagon like peptide 2 receptor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. GLP2R: glucagon like peptide 2 receptor. Genes, record 9340. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/9340

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Gene

Symbol
GLP2R
HGNC
Name
glucagon like peptide 2 receptor
HGNC
NCBI Gene ID
9340
NCBI Gene
HGNC ID
HGNC:4325
HGNC
Ensembl
ENSG00000065325
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O95838Glucagon-like peptide 2 receptor5531Ensembl, GeneID, HGNC

Source UniProt

Patents38

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1447607O95838Espacenet
JP 2025529142 A2025-09-041739O95838Espacenet
US 12371689 B22025-07-291739O95838Espacenet
EP 4541896 A12025-04-23272O95838Espacenet
JP 2025032204 A2025-03-1129090O95838Espacenet
JP 2025010185 A2025-01-20272O95838Espacenet
EP 4461818 A22024-11-1329090O95838Espacenet
JP 2023184465 A2023-12-28272O95838Espacenet
WO 2023243495 A2023-12-21272O95838Espacenet
JP 2023058610 A2023-04-2529090O95838Espacenet

1 to 10 of 38

See all 38 patents

Drugs3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ELSIGLUTIDECHEMBL2108318Glucagon-like peptide 2 receptor agonistAGONISTChEMBL
FE 203799CHEMBL4563522Glucagon-like peptide 2 receptor agonistAGONISTChEMBL
TEDUGLUTIDECHEMBL2104987Glucagon-like peptide 2 receptor agonistAGONISTChEMBL

Trials30

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07400783TEDUGLUTIDEClinicalTrials.gov
NCT06973304TEDUGLUTIDEPHASE3ClinicalTrials.gov
NCT05027308TEDUGLUTIDEPHASE32024-05-16ClinicalTrials.gov
NCT05023382TEDUGLUTIDEClinicalTrials.gov
NCT05018286FE 203799PHASE3ClinicalTrials.gov
NCT04964986FE 203799PHASE22025-06-18ClinicalTrials.gov
NCT04857801TEDUGLUTIDEClinicalTrials.gov
NCT04733066TEDUGLUTIDEClinicalTrials.gov
NCT04627025FE 203799PHASE3ClinicalTrials.gov
NCT04290429TEDUGLUTIDEEARLY_PHASE1ClinicalTrials.gov

1 to 10 of 30

See all 30 trials

NIH grants304

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleGLP2R papersNewest fiscal year
P30DK020572Michigan Diabetes Research Center (MDRC)52025
P30DK056338Texas Medical Center Digestive Diseases Center42025
I01BX001245Luminal Factors Affecting Duodenal Protection and Chemosensing22025
P20GM103446Delaware INBRE22025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)22025
P30CA068485Cancer Center Support Grant22025
P30DK056341Washington University Nutrition Obesity Research Center22025
P30ES010126UNC Center for Environmental Health and Susceptibility22025
T32DK007665Metabolism and Nutrition Training Program22025
P20GM109036Tulane COBRE for Clinical and Translational Research in Cardiometabolic Diseases12025

1 to 10 of 304Source NIH's project files

See all 304 nih grants

Papers528

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrative predictive modelling and multi-omics validation reveals potential indicators of clinical heterogeneity in HCC.Biochem Biophys Res Commun202642759273PubTator, text miningPubMed
EVIDENCE OF THE INFLUENCE OF GLUCAGON-LIKE PEPTIDE ANALOGS IN INFLAMMATORY BOWEL DISEASE: A SCOPING REVIEW.Arq Gastroenterol202642615757PubTator, text miningPubMed
Integrative Analysis of Steroid Metabolism-Based Molecular Subtypes Reveals Prognostic Subtypes and Therapeutic Implications in Gastric Cancer.Cancer Inform202642571211PubTator, text miningPubMed
Genetic architecture and cross-platform validation of apolipoprotein A-IV concentrations.Genome Biol202642449406PubTator, text miningPubMed
Glucagon-Like Peptide-2 Receptor: A Master Integrator of Gut-Brain-Liver Communication in Metabolic and Cognitive Health.Compr Physiol202641943399PubTator, text miningPubMed
Exosome-like nanovesicles from acerola for CRISPR-Cas9 ribonucleoprotein delivery to the central nervous system.Mol Ther Nucleic Acids202641909467PubTator, text miningPubMed
Bispecific GLP-1/GLP-2 agonism in advanced type 2 diabetes: preclinical characterization and a randomized, double-blind, placebo-controlled phase I trial.Nat Commun202641876542PubTator, text miningPubMed
Dapiglutide, a dual GLP-1 and GLP-2 receptor agonist, for obesity: a randomised, double-blind, placebo-controlled parallel-group, proof-of-concept trial.EClinicalMedicine202641768273PubTator, text miningPubMed
Identification and Functional Validation of PTH2R as a Therapeutic Target in Lung Adenocarcinoma.Biomedicines202641751388PubTator, text miningPubMed
DNA methylation-mediated silencing of MEOX1 promotes glycolysis and immune evasion in colorectal cancer cells through inhibition of GLP2R transcription.Cell Biosci202641612494PubTator, text miningPubMed

1 to 10 of 528

See all 528 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/9340

GET https://conductscience.org/api/genes/v1/9340/patents?page=2