ConductScience.org, home
Papers
API referenceFor AI assistants

Paper1237376

Intensive immunosuppression in patients with disseminated sclerosis. I. Clinical response.

Lance EM and 5 others. Clin Exp Immunol, 1975. Cited by 36 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

Download JSON
Cite this record

ConductScience Library. Intensive immunosuppression in patients with disseminated sclerosis. I. Clinical response. Papers, record 1237376. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/1237376

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Intensive immunosuppression in patients with disseminated sclerosis. I. Clinical response.
PubMed
Journal
Clin Exp Immunol
PubMed
Year
1975
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
36
iCite
Relative citation ratio, by iCite
1.68
iCite
Revised in PubMed
2021-12-03
PubMed

Authors6

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Lance EME M
2Kremer MM
3Abbosh JJ
4Jones VEV E
5Knight SS
6Medawar PBP B

Source PubMed

Topics21

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Immunosuppression TherapyMajor topic
Multiple SclerosisMajor topic
Adrenal Cortex Hormones
Adult
Anaphylaxis
Animals
Antilymphocyte Serum
Azathioprine
Female
Follow-Up Studies
Horses
Humans
Immunoglobulin G
Infusions, Parenteral
Male
Middle Aged
Phlebitis
Prednisone
Remission, Spontaneous
Serum Sickness
Water-Electrolyte Balance

Source PubMed

References19

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,139,403Intensive immunosuppression in the treatment of multiple sclerosis.Lancet1974https://conductscience.org/library/papers/4139403PubMed
25,035,906Effect of 'maximum immune suppression' with thoracic duct drainage, ALG, azathioprine and cortisone in some neurological disorders.Proc R Soc Med1972https://conductscience.org/library/papers/5035906PubMed
35,403,333Immunological tolerance induced in adult dogs by small amounts of horse IgG.Transplantation1969https://conductscience.org/library/papers/5403333PubMed
44,358,999Evaluation of antithymocyte globulin in acute relapses of multiple sclerosis.Neurology1974https://conductscience.org/library/papers/4358999PubMed
54,394,519The selective action of antilymphocyte serum on recirculating lymphocytes: a review of the evidence and alternatives.Clin Exp Immunol1970https://conductscience.org/library/papers/4394519PubMed
65,473,642In vitro delayed (cellular) hypersensitivity in multiple sclerosis to central nervous system antigens.Int Arch Allergy Appl Immunol1970https://conductscience.org/library/papers/5473642PubMed
714,004,486The use of specific "lymphocyte" antisera to inhibit hypersensitive reactions of the "delayed" type.J Exp Med1961https://conductscience.org/library/papers/14004486PubMed
814,014,027A tissue-culture approach to demyelinative disorders.Natl Cancer Inst Monogr1963https://conductscience.org/library/papers/14014027PubMed
9810,281Intensive immunosuppression in patients with disseminated sclerosis. II. Tolerance to equine IgG and effect on immunoglobulin and complement levels.Clin Exp Immunol1975https://conductscience.org/library/papers/810281PubMed
101,181,076Intensive immunosuppression in patients with disseminated sclerosis. III. Lymphocyte response in vitro.Clin Exp Immunol1975https://conductscience.org/library/papers/1181076PubMed
114,105,313Therapeutic trial of Imuran (azathioprine) in multiple sclerosis.Acta Neurol Scand1971https://conductscience.org/library/papers/4105313PubMed
124,314,823Cooperative study in the evaluation of therapy in multiple sclerosis. ACTH vs. placebo--final report.Neurology1970https://conductscience.org/library/papers/4314823PubMed
134,338,391The treatment of multiple sclerosis.Med Clin North Am1972https://conductscience.org/library/papers/4338391PubMed
144,541,183Failure of antilymphocytic globulin therapy in chronic progressive multiple sclerosis.Neurology1973https://conductscience.org/library/papers/4541183PubMed
154,574,348Multiple sclerosis: a review.Br Med J1973https://conductscience.org/library/papers/4574348PubMed
164,631,348Therapeutic trial of immunosuppressive agents in multiple sclerosis.Neurology1972https://conductscience.org/library/papers/4631348PubMed
174,632,435Long-term treatment of multiple sclerosis with azathioprine.J Neurol Neurosurg Psychiatry1973https://conductscience.org/library/papers/4632435PubMed
184,942,129Effects of cortisol and antilymphocyte serum on lymphoid populations.Ciba Found Study Group1970https://conductscience.org/library/papers/4942129PubMed
194,190,510[Destruction of nerve cells cultured "in vitro" by lymphocytes from patients with multiple sclerosis. Auto-immune pathogenesis of multiple sclerosis].Presse Med (1893)1969https://conductscience.org/library/papers/4190510PubMed

Cited by10

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 36 citations.

PMIDTitleJournalYearIn PapersSource
6,157,007Azathioprine in multiple sclerosis--a 3 year controlled study of its effectiveness.J Neurol1980https://conductscience.org/library/papers/6157007PubMed
6,112,272Retroperitoneal fibrosis and polyarteritis nodosa successfully treated by intensive immunosuppression.J R Soc Med1980https://conductscience.org/library/papers/6112272PubMed
2,915,232Relapse of multiple sclerosis following acute allergic reactions to plasma during plasmapheresis.J Neurol1989https://conductscience.org/library/papers/2915232PubMed
1,181,076Intensive immunosuppression in patients with disseminated sclerosis. III. Lymphocyte response in vitro.Clin Exp Immunol1975https://conductscience.org/library/papers/1181076PubMed
810,281Intensive immunosuppression in patients with disseminated sclerosis. II. Tolerance to equine IgG and effect on immunoglobulin and complement levels.Clin Exp Immunol1975https://conductscience.org/library/papers/810281PubMed
458,481Prolonged azathioprine treatment of non-remitting multiple sclerosis.J Neurol Neurosurg Psychiatry1979https://conductscience.org/library/papers/458481PubMed
322,771[Long-term therapy using horse anti-dog lymphocyte globulin without sensitization against horse protein].Blut1977https://conductscience.org/library/papers/322771PubMed
202,967The evidence justifying immunosuppression therapy in multiple sclerosis.Proc R Soc Med1977https://conductscience.org/library/papers/202967PubMed
72,790Failure of basic protein therapy for multiple sclerosis.J Neurol1977https://conductscience.org/library/papers/72790PubMed
65,452Intensive immunosuppression with cyclophosphamide in multiple sclerosis. Follow up of 110 patients for 2-6 years.J Neurol1977https://conductscience.org/library/papers/65452PubMed

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Genes
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this paper from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/papers/v1/1237376

GET https://conductscience.org/api/papers/v1/1237376/authors

API referenceFor AI assistants