Paper · 18321663
Two of four alternatively spliced isoforms of RUNX2 control osteocalcin gene expression in human osteoblast cells.
Makita N and 7 others. Gene, 2008. Cited by 45 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
Cite this record
ConductScience Library. Two of four alternatively spliced isoforms of RUNX2 control osteocalcin gene expression in human osteoblast cells. Papers, record 18321663. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/18321663
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Two of four alternatively spliced isoforms of RUNX2 control osteocalcin gene expression in human osteoblast cells.
- PubMed
Topics26
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Core Binding Factor Alpha 1 Subunit | Major topic |
| Osteoblasts | Major topic |
| Osteocalcin | Major topic |
| Alternative Splicing | |
| Base Sequence | |
| Binding Sites | |
| Cell Differentiation | |
| Cell Line, Tumor | |
| Cell Nucleus | |
| Cells, Cultured | |
| Chondrocytes | |
| Chondrosarcoma | |
| Cytosol | |
| DNA Primers | |
| Gene Expression Regulation | |
| Histone Deacetylases | |
| Humans | |
| Mesenchymal Stem Cells | |
| Osteosarcoma | |
| Promoter Regions, Genetic | |
| Protein Isoforms | |
| Recombinant Proteins | |
| Reverse Transcriptase Polymerase Chain Reaction | |
| Transfection | |
| p300-CBP Transcription Factors | |
| Histone Deacetylase 3 |
Source PubMed
Grants0
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None in this release.
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References0
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
None in this release.
Cited by26
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 45 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,286,000 | Integrative multiomic analysis reveals co-ordinated alternative splicing in human bone marrow stromal stem cells. | Sci Rep | 2026 | https://conductscience.org/library/papers/42286000 | PubMed |
| 41,701,118 | Runx2 Regulated Airway Homeostasis Is Disrupted in Asthma. | FASEB J | 2026 | https://conductscience.org/library/papers/41701118 | PubMed |
| 41,602,857 | RNA splicing in bone diseases: mechanisms, pathogenesis and therapeutics. | Acta Biochim Pol | 2025 | https://conductscience.org/library/papers/41602857 | PubMed |
| 41,108,771 | Immunological and tissue reactions to titanium particles generated by the mechanical decontamination of dental implants: In vitro and in vivo study. | Med Oral Patol Oral Cir Bucal | 2026 | https://conductscience.org/library/papers/41108771 | PubMed |
| 40,051,391 | Identification of NIBAN2-Regulated RUNX2 Alternative Splicing Presents Novel Strategies for Antagonizing Osteoporosis. | Adv Sci (Weinh) | 2025 | https://conductscience.org/library/papers/40051391 | PubMed |
| 39,804,499 | The effect of LARP7 on gene expression during osteogenesis. | Mol Biol Rep | 2025 | https://conductscience.org/library/papers/39804499 | PubMed |
| 39,075,952 | Alternative Splicing of Pre-mRNA Matters in Oral Diseases. | Curr Gene Ther | 2025 | https://conductscience.org/library/papers/39075952 | PubMed |
| 37,072,640 | Effect of RNA-binding proteins on osteogenic differentiation of bone marrow mesenchymal stem cells. | Mol Cell Biochem | 2024 | https://conductscience.org/library/papers/37072640 | PubMed |
| 36,943,004 | Splicing factor YBX1 regulates bone marrow stromal cell fate during aging. | EMBO J | 2023 | https://conductscience.org/library/papers/36943004 | PubMed |
| 36,138,061 | Evaluation of the inflammatory and osteogenic response induced by titanium particles released during implantoplasty of dental implants. | Sci Rep | 2022 | https://conductscience.org/library/papers/36138061 | PubMed |
1 to 10 of 26
See all 26 cited byGenes6
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| BGLAP | 632 | PubTator's text mining | https://conductscience.org/library/genes/632 | NCBI Gene |
| CREBBP | 1,387 | PubTator's text mining | https://conductscience.org/library/genes/1387 | NCBI Gene |
| EP300 | 2,033 | PubTator's text mining | https://conductscience.org/library/genes/2033 | NCBI Gene |
| HDAC3 | 8,841 | PubTator's text mining | https://conductscience.org/library/genes/8841 | NCBI Gene |
| LOC110013312 | 110,013,312 | PubTator's text mining | https://conductscience.org/library/genes/110013312 | NCBI Gene |
| RUNX2 | 860 | PubTator's text mining | https://conductscience.org/library/genes/860 | NCBI Gene |
Drugs0
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None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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