Paper · 19089325

Function and dysfunction of mammalian membrane guanylyl cyclase receptors: lessons from genetic mouse models and implications for human diseases.

Kuhn M. Handb Exp Pharmacol, 2009. Cited by 55 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Function and dysfunction of mammalian membrane guanylyl cyclase receptors: lessons from genetic mouse models and implications for human diseases. Papers, record 19089325. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/19089325

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Function and dysfunction of mammalian membrane guanylyl cyclase receptors: lessons from genetic mouse models and implications for human diseases.; PubMed
Journal: Handb Exp Pharmacol; PubMed
Year: 2009; PubMed
Publication types: Journal Article, Research Support, Non-U.S. Gov't, Review; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/19089325/; PubMed
DOI: https://doi.org/10.1007/978-3-540-68964-5_4; PubMed
The journal: https://conductscience.org/library/journal-index/7902231; PubMed
Citations, by iCite: 55; iCite
Relative citation ratio, by iCite: 1.41; iCite
Revised in PubMed: 2008-12-17; PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	Kind	ORCID iD
1	Kuhn M	Michaela

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH term	Major
Guanylate Cyclase	Major topic
Receptors, Guanylate Cyclase-Coupled	Major topic
Signal Transduction	Major topic
Animals
Disease Models, Animal
Humans
Mice
Models, Genetic
Protein Binding
Protein Conformation

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References0

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

None in this release.

Cited by22

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 55 citations.

PMID	Title	Journal	Year	In Papers	Source
41,732,176	Phosphodiesterase inhibitors as emerging therapeutics for skeletal disorders: A comprehensive review of mechanisms and repurposing potential.	Bone Rep	2026	https://conductscience.org/library/papers/41732176	PubMed
37,742,795	Developmental roles of natriuretic peptides and their receptors.	Cells Dev	2023	https://conductscience.org/library/papers/37742795	PubMed
36,349,142	Role of protein phosphorylation in cell signaling, disease, and the intervention therapy.	MedComm (2020)	2022	https://conductscience.org/library/papers/36349142	PubMed
35,216,259	Phosphodiesterases and Compartmentation of cAMP and cGMP Signaling in Regulation of Cardiac Contractility in Normal and Failing Hearts.	Int J Mol Sci	2022	https://conductscience.org/library/papers/35216259	PubMed
33,404,845	Olfactory subsystems associated with the necklace glomeruli in rodents.	Cell Tissue Res	2021	https://conductscience.org/library/papers/33404845	PubMed
32,327,991	Guanylyl Cyclase A/cGMP Signaling Slows Hidden, Age- and Acoustic Trauma-Induced Hearing Loss.	Front Aging Neurosci	2020	https://conductscience.org/library/papers/32327991	PubMed
31,423,565	Mind the gap (junction): cGMP induced by nitric oxide in cardiac myocytes originates from cardiac fibroblasts.	Br J Pharmacol	2019	https://conductscience.org/library/papers/31423565	PubMed
28,963,397	Guanylyl cyclase-G is an alarm pheromone receptor in mice.	EMBO J	2018	https://conductscience.org/library/papers/28963397	PubMed
26,579,459	Current developments in pharmacological therapeutics for chronic constipation.	Acta Pharm Sin B	2015	https://conductscience.org/library/papers/26579459	PubMed
25,452,496	Receptor guanylyl cyclase-G is a novel thermosensory protein activated by cool temperatures.	EMBO J	2015	https://conductscience.org/library/papers/25452496	PubMed

1 to 10 of 22

See all 22 cited by

Genes7

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
GCA	25,801	PubTator's text mining	https://conductscience.org/library/genes/25801	NCBI Gene
GCG	2,641	PubTator's text mining	https://conductscience.org/library/genes/2641	NCBI Gene
GUCY2C	2,984	PubTator's text mining	https://conductscience.org/library/genes/2984	NCBI Gene
GUCY2EP	390,226	PubTator's text mining	https://conductscience.org/library/genes/390226	NCBI Gene
GUCY2F	2,986	PubTator's text mining	https://conductscience.org/library/genes/2986	NCBI Gene
GUCY2GP	390,003	PubTator's text mining	https://conductscience.org/library/genes/390003	NCBI Gene
NPR2	4,882	PubTator's text mining	https://conductscience.org/library/genes/4882	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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