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Paper26344744

Peptide Dose and/or Structure in Vaccines as a Determinant of T Cell Responses.

Leggatt GR. Vaccines (Basel), 2014. Cited by 10 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Peptide Dose and/or Structure in Vaccines as a Determinant of T Cell Responses. Papers, record 26344744. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/26344744

Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Peptide Dose and/or Structure in Vaccines as a Determinant of T Cell Responses.
PubMed
Journal
Vaccines (Basel)
PubMed
Year
2014
PubMed
Publication types
Journal Article, Review
PubMed
Citations, by iCite
10
iCite
Relative citation ratio, by iCite
0.25
iCite
Revised in PubMed
2020-10-01
PubMed

Authors1

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Leggatt GRGraham R

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

References80

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
19,916,724High avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy.J Immunol1999https://conductscience.org/library/papers/9916724PubMed
222,044,420Selective culling of high avidity antigen-specific CD4+ T cells after virulent Salmonella infection.Immunology2011https://conductscience.org/library/papers/22044420PubMed
317,274,003Secondary immunisation with high-dose heterologous peptide leads to CD8 T cell populations with reduced functional avidity.Eur J Immunol2007https://conductscience.org/library/papers/17274003PubMed
419,355,902Toxic, immunostimulatory and antagonist gluten peptides in celiac disease.Curr Med Chem2009https://conductscience.org/library/papers/19355902PubMed
517,617,563Cutting edge: CD8+ T cell clones possess the potential to differentiate into both high- and low-avidity effector cells.J Immunol2007https://conductscience.org/library/papers/17617563PubMed
612,618,518Chronic myelogenous leukemia shapes host immunity by selective deletion of high-avidity leukemia-specific T cells.J Clin Invest2003https://conductscience.org/library/papers/12618518PubMed
716,498,452Antiviral antibody responses: the two extremes of a wide spectrum.Nat Rev Immunol2006https://conductscience.org/library/papers/16498452PubMed
812,594,278Selective induction of high avidity CTL by altering the balance of signals from APC.J Immunol2003https://conductscience.org/library/papers/12594278PubMed
917,971,817HIV/AIDS vaccines: 2007.Clin Pharmacol Ther2007https://conductscience.org/library/papers/17971817PubMed
1015,879,092Multiple costimulatory modalities enhance CTL avidity.J Immunol2005https://conductscience.org/library/papers/15879092PubMed
1119,252,493The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding.Nat Immunol2009https://conductscience.org/library/papers/19252493PubMed
1223,885,819Combination of adjuvants: the future of vaccine design.Expert Rev Vaccines2013https://conductscience.org/library/papers/23885819PubMed
1310,963,600Progression of autoimmune diabetes driven by avidity maturation of a T-cell population.Nature2000https://conductscience.org/library/papers/10963600PubMed
1417,584,532Maximizing CD8+ T cell responses elicited by peptide vaccines containing CpG oligodeoxynucleotides.Clin Immunol2007https://conductscience.org/library/papers/17584532PubMed
1520,660,617TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo.J Exp Med2010https://conductscience.org/library/papers/20660617PubMed
1624,549,702Decision-making critical amino acids: role in designing peptide vaccines for eliciting Th1 and Th2 immune response.Amino Acids2014https://conductscience.org/library/papers/24549702PubMed
1714,224,412INDUCTION OF IMMUNOLOGICAL PARALYSIS IN TWO ZONES OF DOSAGE.Proc R Soc Lond B Biol Sci1964https://conductscience.org/library/papers/14224412PubMed
1811,160,212High-avidity CTL exploit two complementary mechanisms to provide better protection against viral infection than low-avidity CTL.J Immunol2001https://conductscience.org/library/papers/11160212PubMed
191,833,816Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand.Science1991https://conductscience.org/library/papers/1833816PubMed
207,568,164Major histocompatibility complex binding affinity of an antigenic determinant is crucial for the differential secretion of interleukin 4/5 or interferon gamma by T cells.Proc Natl Acad Sci U S A1995https://conductscience.org/library/papers/7568164PubMed

See all 80 references

Cited by8

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 10 citations.

PMIDTitleJournalYearIn PapersSource
42,510,747A Dendrimer-Based Multiple Antigenic Peptide (MAP) Approach for Dengue Vaccine Development: In Silico and In Vivo Insights on Safety and Effectiveness.Biology (Basel)2026https://conductscience.org/library/papers/42510747PubMed
38,782,542Dose escalation study of a personalized peptide-based neoantigen vaccine (EVX-01) in patients with metastatic melanoma.J Immunother Cancer2024https://conductscience.org/library/papers/38782542PubMed
33,730,591Antigen presentation between T cells drives Th17 polarization under conditions of limiting antigen.Cell Rep2021https://conductscience.org/library/papers/33730591PubMed
33,704,770Constant regulation for stable CD8 T-cell functional avidity and its possible implications for cancer immunotherapy.Eur J Immunol2021https://conductscience.org/library/papers/33704770PubMed
32,194,999Efficacy of FLU-v, a broad-spectrum influenza vaccine, in a randomized phase IIb human influenza challenge study.NPJ Vaccines2020https://conductscience.org/library/papers/32194999PubMed
31,846,475Immune responses to a HSV-2 polynucleotide immunotherapy COR-1 in HSV-2 positive subjects: A randomized double blinded phase I/IIa trial.PLoS One2019https://conductscience.org/library/papers/31846475PubMed
28,329,211Therapeutic Vaccine for Genital Herpes Simplex Virus-2 Infection: Findings From a Randomized Trial.J Infect Dis2017https://conductscience.org/library/papers/28329211PubMed
27,642,756On Peptides and Altered Peptide Ligands: From Origin, Mode of Action and Design to Clinical Application (Immunotherapy).Int Arch Allergy Immunol2016https://conductscience.org/library/papers/27642756PubMed

Genes8

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
CD4920PubTator's text mininghttps://conductscience.org/library/genes/920NCBI Gene
CD8A925PubTator's text mininghttps://conductscience.org/library/genes/925NCBI Gene
CYCS54,205PubTator's text mininghttps://conductscience.org/library/genes/54205NCBI Gene
HLA-C3,107PubTator's text mininghttps://conductscience.org/library/genes/3107NCBI Gene
IL153,600PubTator's text mininghttps://conductscience.org/library/genes/3600NCBI Gene
PMEL6,490PubTator's text mininghttps://conductscience.org/library/genes/6490NCBI Gene
RAG15,896PubTator's text mininghttps://conductscience.org/library/genes/5896NCBI Gene
TRBV20OR9-26,962PubTator's text mininghttps://conductscience.org/library/genes/6962NCBI Gene

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

None in this release

  • Grants
  • Trials
  • Comments and corrections
  • Drugs
  • Data

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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