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Paper · 26729151

Cadmium Chloride Induces DNA Damage and Apoptosis of Human Liver Carcinoma Cells via Oxidative Stress.

Skipper A and 3 others. Int J Environ Res Public Health, 2016. Cited by 98 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Cadmium Chloride Induces DNA Damage and Apoptosis of Human Liver Carcinoma Cells via Oxidative Stress. Papers, record 26729151. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/26729151

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Cadmium Chloride Induces DNA Damage and Apoptosis of Human Liver Carcinoma Cells via Oxidative Stress.
PubMed
Journal
Int J Environ Res Public Health
PubMed
Year
2016
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
98
iCite
Relative citation ratio, by iCite
5.25
iCite
Revised in PubMed
2018-12-02
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Skipper AAnthony
2Sims JNJennifer N
3Yedjou CGClement G
4Tchounwou PBPaul B

Source PubMed

Topics9

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
ApoptosisMajor topic
Cadmium ChlorideMajor topic
Cell SurvivalMajor topic
DNA DamageMajor topic
Environmental PollutantsMajor topic
Oxidative StressMajor topic
Comet Assay
Hep G2 Cells
Humans

Source PubMed

Grants4

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
G12 MD007581NIMHD NIH HHSUnited StatesG12MD007581PubMed and NIHNIH RePORTER
P20 GM103476NIGMS NIH HHSUnited StatesP20GM103476PubMed and NIHNIH RePORTER
G12MD007581NIMHD NIH HHSUnited StatesG12MD007581PubMed and NIHNIH RePORTER
P20GM103476NIGMS NIH HHSUnited StatesP20GM103476PubMed and NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References52

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
111,337,108Antioxidant effects of alpha tocopherol, ascorbic acid and L-methionine on lead induced oxidative stress to the liver, kidney and brain in rats.Toxicology2001https://conductscience.org/library/papers/11337108PubMed
29,373,618The isoprostanes: unique bioactive products of lipid peroxidation.Prog Lipid Res1997https://conductscience.org/library/papers/9373618PubMed
39,710,155Cadmium induces apoptosis differentially on immune system cell lines.Toxicology1998https://conductscience.org/library/papers/9710155PubMed
41,303,963Is cadmium genotoxic?IARC Sci Publ1992https://conductscience.org/library/papers/1303963PubMed
525,506,409D-Glucose-Induced Cytotoxic, Genotoxic, and Apoptotic Effects on Human Breast Adenocarcinoma (MCF-7) Cells.J Cancer Sci Ther2014https://conductscience.org/library/papers/25506409PubMed
62,722,798Lowering extracellular pH evokes inositol polyphosphate formation and calcium mobilization.J Biol Chem1989https://conductscience.org/library/papers/2722798PubMed
715,004,294The comet assay for DNA damage and repair: principles, applications, and limitations.Mol Biotechnol2004https://conductscience.org/library/papers/15004294PubMed
825,355,157Silver nanoparticle-induced oxidative stress-dependent toxicity in Sprague-Dawley rats.Mol Cell Biochem2015https://conductscience.org/library/papers/25355157PubMed
96,525,509Effects of Pb2+ and Cd2+ on acetylcholine release and Ca2+ movements in synaptosomes and subcellular fractions from rat brain and Torpedo electric organ.Brain Res1984https://conductscience.org/library/papers/6525509PubMed
101,330,026Cadmium block of calcium current in frog sympathetic neurons.Biophys J1992https://conductscience.org/library/papers/1330026PubMed

1 to 10 of 52

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Cited by45

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 98 citations.

PMIDTitleJournalYearIn PapersSource
42,908,969The genotoxic burden of toxic metals: bridging molecular mechanisms, biomonitoring, and multidisciplinary interventions.Front Toxicol2026https://conductscience.org/library/papers/42908969PubMed
42,718,678Role of endoplasmic reticulum stress-mediated autophagy in cadmium-induced apoptosis in BRL-3A cells.Front Vet Sci2026https://conductscience.org/library/papers/42718678PubMed
42,223,729Modified and activated clinoptilolites ameliorate the cadmium and lead-induced genotoxicity in eukaryotic cells.Environ Geochem Health2026https://conductscience.org/library/papers/42223729PubMed
42,152,679Diverse stresses differentially regulate rRNA biogenesis and mRNA translation.Nucleic Acids Res2026https://conductscience.org/library/papers/42152679PubMed
41,373,680Heavy Metal-Contaminated Soils and Gastric Cancer Risk: Molecular Insights and the Relevance of a One Health Perspective.Int J Mol Sci2025https://conductscience.org/library/papers/41373680PubMed
40,683,376Metals in the human liver: An underappreciated risk factor of hepatic insulin resistance and associated pathophysiology.Environ Pollut2025https://conductscience.org/library/papers/40683376PubMed
40,559,573Modulation of TvRAD51 Recombinase in Trichomonas vaginalis by Zinc and Cadmium as a Potential Mechanism for Genotoxic Stress Response.Pathogens2025https://conductscience.org/library/papers/40559573PubMed
40,488,626The effects of developmental cadmium exposure on health and disease.Dis Model Mech2025https://conductscience.org/library/papers/40488626PubMed
40,241,168Mitigation of cadmium toxicity in African catfish using biological Nano chitosan: insights into biochemical, genotoxic, and histopathological effects.BMC Vet Res2025https://conductscience.org/library/papers/40241168PubMed
39,771,090The Mechanisms of Cadmium Toxicity in Living Organisms.Toxics2024https://conductscience.org/library/papers/39771090PubMed

1 to 10 of 45

See all 45 cited by

Genes6

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ANXA5308PubTator's text mininghttps://conductscience.org/library/genes/308NCBI Gene
FOS2,353PubTator's text mininghttps://conductscience.org/library/genes/2353NCBI Gene
JUN3,725PubTator's text mininghttps://conductscience.org/library/genes/3725NCBI Gene
MYC4,609PubTator's text mininghttps://conductscience.org/library/genes/4609NCBI Gene
POLB5,423PubTator's text mininghttps://conductscience.org/library/genes/5423NCBI Gene
SOD16,647PubTator's text mininghttps://conductscience.org/library/genes/6647NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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