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INCB054828 (pemigatinib), a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3, displays activity against genetically defined tumor models.
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Paper · 32315352

Cited by85

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 144 citations.

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PMIDTitleJournalYearIn PapersSource
42,679,332Sequencing of Fibroblast Growth Factor Receptor Inhibitors in Cholangiocarcinoma: A Review of Published Cases.JCO Precis Oncol2026https://conductscience.org/library/papers/42679332PubMed
42,177,363FGFR3 oncogenic activation drives oxidative metabolic reprogramming in bladder cancer: a systems metabolomics approach.Commun Biol2026https://conductscience.org/library/papers/42177363PubMed
42,058,998FGFR alterations and potential role of FGFR inhibitors in pediatric brain tumors.Neurooncol Adv2026https://conductscience.org/library/papers/42058998PubMed
41,420,106Mechanisms of resistance to VHL loss-induced genetic and pharmacological vulnerabilities.EMBO Mol Med2026https://conductscience.org/library/papers/41420106PubMed
41,226,200Protein-Ligand Interactions in Cardiometabolic Drug Targets: Focus on Weight Loss and Cardioprotection.Molecules2025https://conductscience.org/library/papers/41226200PubMed
41,090,357Pharmacologic inhibition of IRE1α-dependent decay protects alveolar epithelial identity and prevents pulmonary fibrosis in mice.J Clin Invest2025https://conductscience.org/library/papers/41090357PubMed
41,084,837Dabogratinib (TYRA-300), an FGFR3 Isoform-Selective Inhibitor: Preclinical and Initial Clinical Evidence of Antitumor Activity.Mol Cancer Ther2026https://conductscience.org/library/papers/41084837PubMed
41,002,392FGFR1 Inhibition by Pemigatinib Enhances Radiosensitivity in Glioblastoma Stem Cells Through S100A4 Downregulation.Cells2025https://conductscience.org/library/papers/41002392PubMed
40,781,553Exploiting collateral sensitivity in the evolution of resistance to tyrosine kinase inhibitors in soft tissue sarcomas.Commun Biol2025https://conductscience.org/library/papers/40781553PubMed
40,762,256Protein kinase B inhibitors enhance the sensitivity of translocated promoter region-fibroblast growth factor receptor 1 cells to fibroblast growth factor receptor 1 inhibitor-induced apoptosis.J Int Med Res2025https://conductscience.org/library/papers/40762256PubMed
40,693,603Targeted therapies and immunotherapies for unresectable cholangiocarcinoma.Chin Med J (Engl)2025https://conductscience.org/library/papers/40693603PubMed
40,386,584Safety and efficacy of pemigatinib in patients with cholangiocarcinoma: a systematic review.J Gastrointest Oncol2025https://conductscience.org/library/papers/40386584PubMed
40,205,008FGFR as a Predictive Marker for Targeted Therapy in Gastrointestinal Malignancies: A Systematic Review.J Gastrointest Cancer2025https://conductscience.org/library/papers/40205008PubMed
40,014,401Identification of potent biparatopic antibodies targeting FGFR2 fusion-driven cholangiocarcinoma.J Clin Invest2025https://conductscience.org/library/papers/40014401PubMed
39,974,639A Comprehensive Review of Current Approaches in Bladder Cancer Treatment.ACS Pharmacol Transl Sci2025https://conductscience.org/library/papers/39974639PubMed
39,911,278Integrative Bioinformatics Analysis for Targeting Hub Genes in Hepatocellular Carcinoma Treatment.Curr Genomics2025https://conductscience.org/library/papers/39911278PubMed
39,764,422Targeted therapies and molecular targets in the therapeutic landscape of advanced urothelial carcinoma: state of the art and future perspectives.Explor Target Antitumor Ther2024https://conductscience.org/library/papers/39764422PubMed
39,543,657Clinical advances and challenges in targeting FGF/FGFR signaling in lung cancer.Mol Cancer2024https://conductscience.org/library/papers/39543657PubMed
39,506,152Coordinated inheritance of extrachromosomal DNAs in cancer cells.Nature2024https://conductscience.org/library/papers/39506152PubMed
39,402,677iPSC-derived megakaryocytes and platelets accelerate wound healing and angiogenesis.Stem Cell Res Ther2024https://conductscience.org/library/papers/39402677PubMed

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  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
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  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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