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Paper · 41226200

Protein-Ligand Interactions in Cardiometabolic Drug Targets: Focus on Weight Loss and Cardioprotection.

Petsas E and 5 others. Molecules, 2025. Cited by 4 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Protein-Ligand Interactions in Cardiometabolic Drug Targets: Focus on Weight Loss and Cardioprotection. Papers, record 41226200. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41226200

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Protein-Ligand Interactions in Cardiometabolic Drug Targets: Focus on Weight Loss and Cardioprotection.
PubMed
Journal
Molecules
PubMed
Year
2025
PubMed
Publication types
Journal Article, Review
PubMed
Citations, by iCite
4
iCite
Revised in PubMed
2026-09-18
PubMed

Authors6

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Petsas EErrikoshttps://orcid.org/0009-0001-3805-6558
2Kiouri DPDespoina Phttps://orcid.org/0009-0004-5104-8044
3Georgiou NNikitashttps://orcid.org/0000-0002-3226-7434
4Siasos GGerasimos
5Mavromoustakos TThomashttps://orcid.org/0000-0001-5309-992X
6Chasapis CTChristos T

Source PubMed

Topics7

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Cardiovascular DiseasesMajor topic
Weight LossMajor topic
Cardiotonic AgentsMajor topic
Humans
Ligands
Animals
Protein Binding

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections1

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

KindPMIDTitleIn Papers
Erratum in41,752,531Correction: Petsas et al. Protein-Ligand Interactions in Cardiometabolic Drug Targets: Focus on Weight Loss and Cardioprotection. Molecules 2025, 30, 4240.https://conductscience.org/library/papers/41752531

Source PubMed

References192

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
110,490,103Structural basis for FGF receptor dimerization and activation.Cell1999https://conductscience.org/library/papers/10490103PubMed
224,151,975Palifermin for the protection and regeneration of epithelial tissues following injury: new findings in basic research and pre-clinical models.J Cell Mol Med2013https://conductscience.org/library/papers/24151975PubMed
328,665,128
Discovery of the Irreversible Covalent FGFR Inhibitor 8-(3-(4-Acryloylpiperazin-1-yl)propyl)-6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (PRN1371) for the Treatment of Solid Tumors.
J Med Chem2017https://conductscience.org/library/papers/28665128PubMed
432,449,510Lenvatinib suppresses cancer stem-like cells in HCC by inhibiting FGFR1-3 signaling, but not FGFR4 signaling.Carcinogenesis2021https://conductscience.org/library/papers/32449510PubMed
527,231,792A Systematic Review of PCSK9 Inhibitors Alirocumab and Evolocumab.J Manag Care Spec Pharm2016https://conductscience.org/library/papers/27231792PubMed
633,239,432FDA Approval Summary: Selpercatinib for the Treatment of Lung and Thyroid Cancers with RET Gene Mutations or Fusions.Clin Cancer Res2021https://conductscience.org/library/papers/33239432PubMed
731,715,423Molecular insight of regorafenib treatment for colorectal cancer.Cancer Treat Rev2019https://conductscience.org/library/papers/31715423PubMed
839,559,664Obesity Medications and Their Impact on Cardiovascular Health: A Narrative Review.Cureus2024https://conductscience.org/library/papers/39559664PubMed
939,254,428Influence of Trp-Cage on the Function and Stability of GLP-1R Agonist Exenatide Derivatives.J Med Chem2024https://conductscience.org/library/papers/39254428PubMed
1024,762,441Neuronal GLP1R mediates liraglutide's anorectic but not glucose-lowering effect.J Clin Invest2014https://conductscience.org/library/papers/24762441PubMed

1 to 10 of 192

See all 192 references

Cited by2

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 4 citations.

PMIDTitleJournalYearIn PapersSource
42,351,639Targeting the Crosstalk Between Metabolism and Chronic Inflammation: In Silico Multitargeting Drug Design Approach for Cardiometabolic Syndrome.Biomedicines2026https://conductscience.org/library/papers/42351639PubMed
41,752,531Correction: Petsas et al. Protein-Ligand Interactions in Cardiometabolic Drug Targets: Focus on Weight Loss and Cardioprotection. Molecules 2025, 30, 4240.Molecules2026https://conductscience.org/library/papers/41752531PubMed

Genes7

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
FGFR12,260PubTator's text mininghttps://conductscience.org/library/genes/2260NCBI Gene
GIPR2,696PubTator's text mininghttps://conductscience.org/library/genes/2696NCBI Gene
GLP1R2,740PubTator's text mininghttps://conductscience.org/library/genes/2740NCBI Gene
KLB152,831PubTator's text mininghttps://conductscience.org/library/genes/152831NCBI Gene
NFKB14,790PubTator's text mininghttps://conductscience.org/library/genes/4790NCBI Gene
NLRP3114,548PubTator's text mininghttps://conductscience.org/library/genes/114548NCBI Gene
PCSK9255,738PubTator's text mininghttps://conductscience.org/library/genes/255738NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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