Paper · 41002392
FGFR1 Inhibition by Pemigatinib Enhances Radiosensitivity in Glioblastoma Stem Cells Through S100A4 Downregulation.
Gouazé-Andersson V and 5 others. Cells, 2025. Cited by 1 paper, by iCite.
11 sourcespapers-2026-11-12-0.1.0
Cite this record
ConductScience Library. FGFR1 Inhibition by Pemigatinib Enhances Radiosensitivity in Glioblastoma Stem Cells Through S100A4 Downregulation. Papers, record 41002392. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41002392
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- FGFR1 Inhibition by Pemigatinib Enhances Radiosensitivity in Glioblastoma Stem Cells Through S100A4 Downregulation.
- PubMed
Topics17
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Glioblastoma | Major topic |
| Neoplastic Stem Cells | Major topic |
| Radiation Tolerance | Major topic |
| S100 Calcium-Binding Protein A4 | Major topic |
| Receptor, Fibroblast Growth Factor, Type 1 | Major topic |
| Down-Regulation | Major topic |
| Brain Neoplasms | Major topic |
| Morpholines | Major topic |
| Pyrimidines | Major topic |
| Humans | |
| Animals | |
| Cell Line, Tumor | |
| Mice | |
| Xenograft Model Antitumor Assays | |
| Mice, Nude | |
| Signal Transduction | |
| Gene Expression Regulation, Neoplastic |
Source PubMed
Grants1
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by |
|---|---|---|---|---|
| EU-FR-ST-20126 EU-FR-ST-20001 | Incyte (United States) | PubMed |
Source PubMed
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References43
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 28,122,245 | Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma. | Cell Rep | 2017 | https://conductscience.org/library/papers/28122245 | PubMed |
| 2 | 32,315,352 | INCB054828 (pemigatinib), a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3, displays activity against genetically defined tumor models. | PLoS One | 2020 | https://conductscience.org/library/papers/32315352 | PubMed |
| 3 | 30,894,200 | Longitudinal heterogeneity in glioblastoma: moving targets in recurrent versus primary tumors. | J Transl Med | 2019 | https://conductscience.org/library/papers/30894200 | PubMed |
| 4 | 29,316,430 | Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment. | Cancer Cell | 2018 | https://conductscience.org/library/papers/29316430 | PubMed |
| 5 | 30,710,284 | The Multifaceted S100A4 Protein in Cancer and Inflammation. | Methods Mol Biol | 2019 | https://conductscience.org/library/papers/30710284 | PubMed |
| 6 | 30,909,436 | Alpha6-Integrin Regulates FGFR1 Expression through the ZEB1/YAP1 Transcription Complex in Glioblastoma Stem Cells Resulting in Enhanced Proliferation and Stemness. | Cancers (Basel) | 2019 | https://conductscience.org/library/papers/30909436 | PubMed |
| 7 | 38,838,500 | An open-label study of pemigatinib in cholangiocarcinoma: final results from FIGHT-202. | ESMO Open | 2024 | https://conductscience.org/library/papers/38838500 | PubMed |
| 8 | 35,420,673 | EGFR Inhibition Potentiates FGFR Inhibitor Therapy and Overcomes Resistance in FGFR2 Fusion-Positive Cholangiocarcinoma. | Cancer Discov | 2022 | https://conductscience.org/library/papers/35420673 | PubMed |
| 9 | 29,260,225 | Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma: A Randomized Clinical Trial. | JAMA | 2017 | https://conductscience.org/library/papers/29260225 | PubMed |
| 10 | 32,805,233 | S100A4/Nonmuscle Myosin IIA/p53 Axis Contributes to Aggressive Features in Ovarian High-Grade Serous Carcinoma. | Am J Pathol | 2020 | https://conductscience.org/library/papers/32805233 | PubMed |
1 to 10 of 43
See all 43 referencesCited by1
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 1 citation.
| PMID | Title | Journal | Year | In Papers |
|---|---|---|---|---|
| 42,415,204 | CD13 identifies S100A4+ immunosuppressive monocytes and predicts temozolomide benefit in glioblastoma. | Biol Direct | 2026 | https://conductscience.org/library/papers/42415204 |
Source PubMed
Genes41
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| AKT1 | 207 | PubTator's text mining | https://conductscience.org/library/genes/207 | NCBI Gene |
| ALK | 238 | PubTator's text mining | https://conductscience.org/library/genes/238 | NCBI Gene |
| ANXA2 | 302 | PubTator's text mining | https://conductscience.org/library/genes/302 | NCBI Gene |
| CETN1 | 1,068 | PubTator's text mining | https://conductscience.org/library/genes/1068 | NCBI Gene |
| EGFR | 1,956 | PubTator's text mining | https://conductscience.org/library/genes/1956 | NCBI Gene |
| EPHB2 | 2,048 | PubTator's text mining | https://conductscience.org/library/genes/2048 | NCBI Gene |
| FGF11 | 2,256 | PubTator's text mining | https://conductscience.org/library/genes/2256 | NCBI Gene |
| FGF2 | 2,247 | PubTator's text mining | https://conductscience.org/library/genes/2247 | NCBI Gene |
| FGFR1 | 2,260 | PubTator's text mining | https://conductscience.org/library/genes/2260 | NCBI Gene |
| FGFR2 | 2,263 | PubTator's text mining | https://conductscience.org/library/genes/2263 | NCBI Gene |
1 to 10 of 41
See all 41 genesDrugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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