Paper35967390
Impaired sweating in patients with cholinergic urticaria is linked to low expression of acetylcholine receptor CHRM3 and acetylcholine esterase in sweat glands.
Wang Y and 7 others. Front Immunol, 2022. Cited by 11 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. Impaired sweating in patients with cholinergic urticaria is linked to low expression of acetylcholine receptor CHRM3 and acetylcholine esterase in sweat glands. Papers, record 35967390. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/35967390
Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
- Title
- Impaired sweating in patients with cholinergic urticaria is linked to low expression of acetylcholine receptor CHRM3 and acetylcholine esterase in sweat glands.
- PubMed
Topics9
NLM's MeSH indexing of the paper, its major topics first.
| MeSH term | Major |
|---|---|
| Acetylcholinesterase | Major topic |
| Receptor, Muscarinic M3 | Major topic |
| Sweat Glands | Major topic |
| Sweating | Major topic |
| Urticaria | Major topic |
| Acetylcholine | |
| Cholinergic Agents | |
| Humans | |
| Receptors, Cholinergic |
Source PubMed
References44
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 2 | 3,827,277 | Cholinergic urticaria. A clinical and histologic study. | Arch Dermatol | 1987 | https://conductscience.org/library/papers/3827277 | PubMed |
| 3 | 28,873,238 | Cholinergic urticaria patients of different age groups have distinct features. | Clin Exp Allergy | 2017 | https://conductscience.org/library/papers/28873238 | PubMed |
| 4 | 21,364,312 | Rapid desensitization with autologous sweat in cholinergic urticaria. | Allergol Int | 2011 | https://conductscience.org/library/papers/21364312 | PubMed |
| 5 | 19,930,398 | Recommendations for performing and evaluating the results of the minor test according to a sweating intensity visual scale. | Dermatol Surg | 2010 | https://conductscience.org/library/papers/19930398 | PubMed |
| 6 | 20,143,437 | Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma. | Cancer | 2010 | https://conductscience.org/library/papers/20143437 | PubMed |
| 7 | 23,748,235 | Decreased expression of acetylcholine esterase in cholinergic urticaria with hypohidrosis or anhidrosis. | J Invest Dermatol | 2014 | https://conductscience.org/library/papers/23748235 | PubMed |
| 8 | 5,593,413 | [On the pathogenesis of cholinergic urticaria. I. Clinical observations and histological studies]. | Arch Klin Exp Dermatol | 1967 | https://conductscience.org/library/papers/5593413 | PubMed |
| 9 | 17,135,748 | Cholinergic urticaria and hypohidrosis: a clinical reappraisal. | Dermatology | 2006 | https://conductscience.org/library/papers/17135748 | PubMed |
| 10 | 28,632,196 | Drug Hypersensitivity and Desensitizations: Mechanisms and New Approaches. | Int J Mol Sci | 2017 | https://conductscience.org/library/papers/28632196 | PubMed |
| 11 | 30,368,007 | Angioedema frequently occurs in cholinergic urticaria. | J Allergy Clin Immunol Pract | 2019 | https://conductscience.org/library/papers/30368007 | PubMed |
| 12 | 7,962,780 | Prevalence of cholinergic urticaria in young adults. | J Am Acad Dermatol | 1994 | https://conductscience.org/library/papers/7962780 | PubMed |
| 13 | 34,954,198 | An open-label, proof-of-concept study of lirentelimab for antihistamine-resistant chronic spontaneous and inducible urticaria. | J Allergy Clin Immunol | 2022 | https://conductscience.org/library/papers/34954198 | PubMed |
| 14 | 24,522,090 | Development and validation of the Urticaria Control Test: a patient-reported outcome instrument for assessing urticaria control. | J Allergy Clin Immunol | 2014 | https://conductscience.org/library/papers/24522090 | PubMed |
| 15 | 20,613,776 | Cholinergic urticaria: studies on the muscarinic cholinergic receptor M3 in anhidrotic and hypohidrotic skin. | J Invest Dermatol | 2010 | https://conductscience.org/library/papers/20613776 | PubMed |
| 16 | 28,714,085 | Neural control of sweat secretion: a review. | Br J Dermatol | 2018 | https://conductscience.org/library/papers/28714085 | PubMed |
| 17 | 29,869,790 | Updosing of bilastine is effective in moderate to severe chronic spontaneous urticaria: A real-life study. | Allergy | 2018 | https://conductscience.org/library/papers/29869790 | PubMed |
| 18 | 15,505,168 | Idiopathic pure sudomotor failure: anhidrosis due to deficits in cholinergic transmission. | Neurology | 2004 | https://conductscience.org/library/papers/15505168 | PubMed |
| 19 | 3,954,930 | Effects of locally administered anticholinesterase agents on the secretory response of human eccrine sweat glands to acetylcholine and carbachol. | Br J Clin Pharmacol | 1986 | https://conductscience.org/library/papers/3954930 | PubMed |
| 20 | 11,069,522 | Cholinergic urticaria associated with acquired generalized hypohidrosis: report of a case and review of the literature. | Br J Dermatol | 2000 | https://conductscience.org/library/papers/11069522 | PubMed |
| 21 | 21,371,134 | Cholinergic urticaria: pathogenesis-based categorization and its treatment options. | J Eur Acad Dermatol Venereol | 2012 | https://conductscience.org/library/papers/21371134 | PubMed |
Cited by10
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 11 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,851,414 | Scoping review: biomarkers in chronic inducible urticaria. | Front Immunol | 2026 | https://conductscience.org/library/papers/42851414 | PubMed |
| 42,327,770 | Chronic spontaneous cholinergic urticaria: advances in immunological mechanisms focusing on neuro-immune crosstalk and novel targeted therapeutic strategies. | Front Immunol | 2026 | https://conductscience.org/library/papers/42327770 | PubMed |
| 42,112,401 | Advancements and challenges in the management of chronic inducible urticaria. | Front Immunol | 2026 | https://conductscience.org/library/papers/42112401 | PubMed |
| 41,856,079 | Sweat components as a promising monitoring tool for systemic diseases. | J Physiol Sci | 2026 | https://conductscience.org/library/papers/41856079 | PubMed |
| 40,069,822 | Beyond the itch: the complex interplay of immune, neurological, and psychological factors in chronic urticaria. | J Neuroinflammation | 2025 | https://conductscience.org/library/papers/40069822 | PubMed |
| 39,028,396 | New insights into chronic inducible urticaria. | Curr Allergy Asthma Rep | 2024 | https://conductscience.org/library/papers/39028396 | PubMed |
| 38,731,882 | Altered Sweat Composition Due to Changes in Tight Junction Expression of Sweat Glands in Cholinergic Urticaria Patients. | Int J Mol Sci | 2024 | https://conductscience.org/library/papers/38731882 | PubMed |
| 38,432,889 | Research progress in the pathogenesis of chronic urticaria. | Zhong Nan Da Xue Xue Bao Yi Xue Ban | 2023 | https://conductscience.org/library/papers/38432889 | PubMed |
| 38,308,655 | Targeting histamine receptor 4 in cholinergic urticaria with izuforant (LEO 152020): results from a phase IIa randomized double-blind placebo-controlled multicentre crossover trial. | Br J Dermatol | 2024 | https://conductscience.org/library/papers/38308655 | PubMed |
| 36,302,805 | Cross-sectional study of cholinergic urticaria subtypes and bronchial hyperresponsiveness. | Sci Rep | 2022 | https://conductscience.org/library/papers/36302805 | PubMed |
Genes5
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| ACHE | 43 | PubTator's text mining | https://conductscience.org/library/genes/43 | NCBI Gene |
| CHRM3 | 1,131 | PubTator's text mining | https://conductscience.org/library/genes/1131 | NCBI Gene |
| FCER1A | 2,205 | PubTator's text mining | https://conductscience.org/library/genes/2205 | NCBI Gene |
| IGHE | 3,497 | PubTator's text mining | https://conductscience.org/library/genes/3497 | NCBI Gene |
| RHO | 6,010 | PubTator's text mining | https://conductscience.org/library/genes/6010 | NCBI Gene |
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
None in this release
- Grants
- Trials
- Comments and corrections
- Drugs
- Data
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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