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Paper · 36715672

Role of FGF10/FGFR2b Signaling in Homeostasis and Regeneration of Adult Lacrimal Gland and Corneal Epithelium Proliferation.

Finburgh EN and 9 others. Invest Ophthalmol Vis Sci, 2023. Cited by 23 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Role of FGF10/FGFR2b Signaling in Homeostasis and Regeneration of Adult Lacrimal Gland and Corneal Epithelium Proliferation. Papers, record 36715672. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/36715672

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Role of FGF10/FGFR2b Signaling in Homeostasis and Regeneration of Adult Lacrimal Gland and Corneal Epithelium Proliferation.
PubMed
Journal
Invest Ophthalmol Vis Sci
PubMed
Year
2023
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
23
iCite
Relative citation ratio, by iCite
2.66
iCite
Revised in PubMed
2023-04-12
PubMed

Authors10

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Finburgh ENEmma N
2Mauduit OOlivier
3Noguchi TTakako
4Bu JJJennifer J
5Abbas AAAnser A
6Hakim DFDominic F
7Bellusci SSaverio
8Meech RRobyn
9Makarenkova HPHelen P
10Afshari NANatalie A

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Lacrimal ApparatusMajor topic
Epithelium, CornealMajor topic
Adult
Mice
Humans
Animals
Receptor, Fibroblast Growth Factor, Type 2
Fibroblast Growth Factor 10
Inflammation
Regeneration
Homeostasis
Cell Proliferation

Source PubMed

Grants3

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
R01 DE031044NIDCR NIH HHSUnited StatesR01DE031044PubMed and NIHNIH RePORTER
R01 EY026202NEI NIH HHSUnited StatesR01EY026202PubMed and NIHNIH RePORTER
R01 EY028983NEI NIH HHSUnited StatesR01EY028983PubMed and NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References52

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
131,259,892Isolation of Myoepithelial Cells from Adult Murine Lacrimal and Submandibular Glands.J Vis Exp2019https://conductscience.org/library/papers/31259892PubMed
211,062,007FGF10 acts as a major ligand for FGF receptor 2 IIIb in mouse multi-organ development.Biochem Biophys Res Commun2000https://conductscience.org/library/papers/11062007PubMed
31,723,855The role of fibroblast growth factor in eye lens development.Ann N Y Acad Sci1991https://conductscience.org/library/papers/1723855PubMed
410,518,547Fgfr2 is required for limb outgrowth and lung-branching morphogenesis.Proc Natl Acad Sci U S A1999https://conductscience.org/library/papers/10518547PubMed
533,259,380Prevalence of Dry Eye Disease in Africa: A Systematic Review and Meta-analysis.Optom Vis Sci2020https://conductscience.org/library/papers/33259380PubMed
617,213,838FGF10 missense mutations in aplasia of lacrimal and salivary glands (ALSG).Eur J Hum Genet2007https://conductscience.org/library/papers/17213838PubMed
726,369,258Therapeutic uses of FGFs.Semin Cell Dev Biol2016https://conductscience.org/library/papers/26369258PubMed
816,501,574Mutations in different components of FGF signaling in LADD syndrome.Nat Genet2006https://conductscience.org/library/papers/16501574PubMed
919,755,711Differential interactions of FGFs with heparan sulfate control gradient formation and branching morphogenesis.Sci Signal2009https://conductscience.org/library/papers/19755711PubMed
1028,510,629Fibroblast Growth Factor Receptor 2 (FGFR2) Is Required for Meibomian Gland Homeostasis in the Adult Mouse.Invest Ophthalmol Vis Sci2017https://conductscience.org/library/papers/28510629PubMed

1 to 10 of 52

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Cited by15

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 23 citations.

PMIDTitleJournalYearIn PapersSource
42,734,304Systematic Analysis of Stromal-Epithelial Crosstalk Reveals the FGF21-FGFR3 Axis as a Key Driver of Corneal Wound Healing.Invest Ophthalmol Vis Sci2026https://conductscience.org/library/papers/42734304PubMed
42,558,716FGF/FGFR signaling at the immune-stromal interface in autoimmune rheumatic diseases: from tissue remodeling to translational opportunities.Front Immunol2026https://conductscience.org/library/papers/42558716PubMed
42,123,603Advances in Pharmacotherapy and Physiotherapy for Dry Eye Disease: Molecular Mechanisms and Future Directions-A Narrative Literature Review.Int J Mol Sci2026https://conductscience.org/library/papers/42123603PubMed
41,789,845A Cross-Species Hydroquinone Model Replicates Smoking-Related Corneal Endothelial Oxidative Injury and Enables Therapeutic Screening of FGF10.Invest Ophthalmol Vis Sci2026https://conductscience.org/library/papers/41789845PubMed
41,785,988Lacrimal gland organoids: A systematic review on development, characterization, molecular profiling and translational potential in dry eye disease.Exp Eye Res2026https://conductscience.org/library/papers/41785988PubMed
41,121,240FGF10 ameliorates epileptic seizures and related cognitive dysfunction via the FGFR2/CALB1 signaling pathway.J Transl Med2025https://conductscience.org/library/papers/41121240PubMed
40,552,917FGF10 Protects the Corneal Epithelium From Dry Eye-Induced Oxidative and ER Stress Via Upregulation of SLC7A11.Invest Ophthalmol Vis Sci2025https://conductscience.org/library/papers/40552917PubMed
40,456,865An FGFR-p53 developmental signaling axis drives salivary cancer progression.Oncogene2025https://conductscience.org/library/papers/40456865PubMed
40,227,178KGF-2 Alleviates Dry Eye Disease by Regulating the HMGB1/TLR4 Pathway.Invest Ophthalmol Vis Sci2025https://conductscience.org/library/papers/40227178PubMed
39,597,252Advanced Biomaterials for Lacrimal Tissue Engineering: A Review.Materials (Basel)2024https://conductscience.org/library/papers/39597252PubMed

1 to 10 of 15

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Genes13

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
CD19930PubTator's text mininghttps://conductscience.org/library/genes/930NCBI Gene
EGF1,950PubTator's text mininghttps://conductscience.org/library/genes/1950NCBI Gene
FGF102,255PubTator's text mininghttps://conductscience.org/library/genes/2255NCBI Gene
FGF2227,006PubTator's text mininghttps://conductscience.org/library/genes/27006NCBI Gene
FGF32,248PubTator's text mininghttps://conductscience.org/library/genes/2248NCBI Gene
FGF72,252PubTator's text mininghttps://conductscience.org/library/genes/2252NCBI Gene
FGFR22,263PubTator's text mininghttps://conductscience.org/library/genes/2263NCBI Gene
IL1B3,553PubTator's text mininghttps://conductscience.org/library/genes/3553NCBI Gene
MRAP56,246PubTator's text mininghttps://conductscience.org/library/genes/56246NCBI Gene
PTPRC5,788PubTator's text mininghttps://conductscience.org/library/genes/5788NCBI Gene

1 to 10 of 13

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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