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Paper · 367653

Severe combined immunodeficiency disease: a model of T-cell dysfunction.

Dosch HM and 3 others. Clin Exp Immunol, 1978. Cited by 32 papers, by iCite.

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ConductScience Library. Severe combined immunodeficiency disease: a model of T-cell dysfunction. Papers, record 367653. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/367653

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Severe combined immunodeficiency disease: a model of T-cell dysfunction.
PubMed
Journal
Clin Exp Immunol
PubMed
Year
1978
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
32
iCite
Relative citation ratio, by iCite
0.8
iCite
Revised in PubMed
2018-11-13
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Dosch HMH M
2Lee JWJ W
3Gelfand EWE W
4Falk JAJ A

Source PubMed

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Immunologic Deficiency SyndromesMajor topic
Models, BiologicalMajor topic
T-LymphocytesMajor topic
Antibody Formation
B-Lymphocytes
Cells, Cultured
Epithelial Cells
Hemolytic Plaque Technique
Humans
Lymphocyte Cooperation
Rosette Formation
Thymus Gland

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References21

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
172,111Functional differentiation of B lymphocytes in congenital agammaglobulinemia. II. Immunochemical analysis of the in vitro primary immune response.J Immunol1977https://conductscience.org/library/papers/72111PubMed
270,838Macrophage-dependent response of immune human T lymphocytes to PPD in vitro. Influence of HLA-D histocompatibility.Scand J Immunol1977https://conductscience.org/library/papers/70838PubMed
363,746Reconstitution of B and T lymphocyte function in severe combined immunodeficiency disease after transplantation with thymic epithelium.Lancet1976https://conductscience.org/library/papers/63746PubMed
4401,513Generation of human plaque-forming cells in culture: tissue distribution, antigenic and cellular requirements.J Immunol1977https://conductscience.org/library/papers/401513PubMed
5325,144Negative allogeneic effects in vitro. I. Allogeneic T cells markedly suppress the secondary antibody-forming cell response.J Immunol1977https://conductscience.org/library/papers/325144PubMed
6334,978Functional differentiation of B lymphocytes in congenital agammaglobulinemia. I. Generation of hemolytic plaque-forming cells.J Immunol1977https://conductscience.org/library/papers/334978PubMed
7301,152
The necessity for T cell help for human tonsil B cell responses to pokeweed mitogens: induction of DNA synthesis, immunoglobulin, and specific antibody production with a T cell helper factor produced with pokeweed mitogen.
J Immunol1977https://conductscience.org/library/papers/301152PubMed
81,087,209Severe combined immunodeficiency with B lymphocytes: in vitro correction of defective immunoglobulin production by addition of normal T lymphocytes.Clin Exp Immunol1976https://conductscience.org/library/papers/1087209PubMed
94,117,384Adenosine-deaminase deficiency in two patients with severely impaired cellular immunity.Lancet1972https://conductscience.org/library/papers/4117384PubMed
104,138,493Morphological and functional maturation of human thymic epithelium in culture.Nature1974https://conductscience.org/library/papers/4138493PubMed

1 to 10 of 21

See all 21 references

Cited by4

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 32 citations.

PMIDTitleJournalYearIn PapersSource
6,966,988Age-related impairment of the in vitro antibody response in the human.Clin Exp Immunol1980https://conductscience.org/library/papers/6966988PubMed
3,902,872Lymphocyte function in human bone marrow. II. Characterization of an interleukin 2-sensitive T precursor-cell population.J Clin Immunol1985https://conductscience.org/library/papers/3902872PubMed
3,081,578Defective expression of T cell-associated glycoprotein in severe combined immunodeficiency.J Clin Invest1986https://conductscience.org/library/papers/3081578PubMed
313,053Selective toxicity of purine deoxynucleosides for human lymphocyte growth and function.Proc Natl Acad Sci U S A1979https://conductscience.org/library/papers/313053PubMed

Genes2

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
ADA100PubTator's text mininghttps://conductscience.org/library/genes/100NCBI Gene
HLA-A3,105PubTator's text mininghttps://conductscience.org/library/genes/3105NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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