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Paper · 3918306

Use of a cDNA expression vector for isolation of mouse interleukin 2 cDNA clones: expression of T-cell growth-factor activity after transfection of monkey cells.

Yokota T and 5 others. Proc Natl Acad Sci U S A, 1985. Cited by 236 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Use of a cDNA expression vector for isolation of mouse interleukin 2 cDNA clones: expression of T-cell growth-factor activity after transfection of monkey cells. Papers, record 3918306. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/3918306

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Use of a cDNA expression vector for isolation of mouse interleukin 2 cDNA clones: expression of T-cell growth-factor activity after transfection of monkey cells.
PubMed
Journal
Proc Natl Acad Sci U S A
PubMed
Year
1985
PubMed
Publication types
Journal Article
PubMed
Citations, by iCite
236
iCite
Relative citation ratio, by iCite
4.57
iCite
Revised in PubMed
2019-05-01
PubMed

Authors6

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Yokota TT
2Arai NN
3Lee FF
4Rennick DD
5Mosmann TT
6Arai KK

Source PubMed

Topics14

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Interleukin-2Major topic
Amino Acid Sequence
Animals
Base Sequence
Biological Assay
Cell Line
Cloning, Molecular
DNA
Gene Expression Regulation
Genetic Vectors
Haplorhini
Mice
RNA, Messenger
Transfection

Source PubMed

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References26

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
14,559,594Nonchromosomal antibiotic resistance in bacteria: genetic transformation of Escherichia coli by R-factor DNA.Proc Natl Acad Sci U S A1972https://conductscience.org/library/papers/4559594PubMed
26,324,170Structure of the human interleukin 2 gene.Proc Natl Acad Sci U S A1983https://conductscience.org/library/papers/6324170PubMed
3181,845Selective in vitro growth of T lymphocytes from normal human bone marrows.Science1976https://conductscience.org/library/papers/181845PubMed
41,086,323Proliferation of murine thymic lymphocytes in vitro is mediated by the concanavalin A-induced release of a lymphokine (costimulator).J Immunol1976https://conductscience.org/library/papers/1086323PubMed
5271,968DNA sequencing with chain-terminating inhibitors.Proc Natl Acad Sci U S A1977https://conductscience.org/library/papers/271968PubMed
6307,026Partial purification and molecular characterization of a lymphokine (costimulator) required for the mitogenic response of mouse thymocytes in vitro.J Immunol1978https://conductscience.org/library/papers/307026PubMed
7307,029T cell growth factor: parameters of production and a quantitative microassay for activity.J Immunol1978https://conductscience.org/library/papers/307029PubMed
8315,987Biochemical and biological characterization of lymphocyte regulatory molecules. I. Purification of a class of murine lymphokines.J Exp Med1979https://conductscience.org/library/papers/315987PubMed
992,524Continuous proliferation of murine antigen-specific helper T lymphocytes in culture.J Exp Med1979https://conductscience.org/library/papers/92524PubMed
10518,835Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.Biochemistry1979https://conductscience.org/library/papers/518835PubMed

1 to 10 of 26

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Cited by63

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 236 citations.

PMIDTitleJournalYearIn PapersSource
41,710,830Inflammatory Factors and Chronic Rhinosinusitis: An Umbrella Review.Cureus2026https://conductscience.org/library/papers/41710830PubMed
20,215,876A novel functional gene selection method provides a systematic view of cell migration.Cell Adh Migr2010https://conductscience.org/library/papers/20215876PubMed
15,731,332Screening of retroviral cDNA libraries for factors involved in protein phosphorylation in signaling cascades.Nucleic Acids Res2005https://conductscience.org/library/papers/15731332PubMed
15,147,342Induction of hyperthyroidism in mice by intradermal immunization with DNA encoding the thyrotropin receptor.Clin Exp Immunol2004https://conductscience.org/library/papers/15147342PubMed
14,720,307Cloning and characterization of deer mouse (Peromyscus maniculatus) cytokine and chemokine cDNAs.BMC Immunol2004https://conductscience.org/library/papers/14720307PubMed
10,732,769Alteration of tumour response to radiation by interleukin-2 gene transfer.Br J Cancer2000https://conductscience.org/library/papers/10732769PubMed
9,557,697
Recombinant vaccinia virus coexpressing the F protein of respiratory syncytial virus (RSV) and interleukin-4 (IL-4) does not inhibit the development of RSV-specific memory cytotoxic T lymphocytes, whereas priming is diminished in the presence of high levels of IL-2 or gamma interferon.
J Virol1998https://conductscience.org/library/papers/9557697PubMed
8,642,317Characterization of apoptosis-resistant antigen-specific T cells in vivo.J Exp Med1996https://conductscience.org/library/papers/8642317PubMed
8,319,981Existence of at least five interleukin-2 molecules in different mouse strains.Immunogenetics1993https://conductscience.org/library/papers/8319981PubMed
8,188,376Recombinant Mycobacterium bovis BCG secreting functional interleukin-2 enhances gamma interferon production by splenocytes.Infect Immun1994https://conductscience.org/library/papers/8188376PubMed

1 to 10 of 63

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Genes1

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn Genes
IL23,558PubTator's text mininghttps://conductscience.org/library/genes/3558

Source NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data1

The data bank entries PubMed's record names. Trial numbers are under Trials.

Data bankAccession
GENBANKK02292

Source GENBANK

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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