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Paper · 39200096

Diabetes and Osteoarthritis: Exploring the Interactions and Therapeutic Implications of Insulin, Metformin, and GLP-1-Based Interventions.

Halabitska I and 3 others. Biomedicines, 2024. Cited by 43 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Diabetes and Osteoarthritis: Exploring the Interactions and Therapeutic Implications of Insulin, Metformin, and GLP-1-Based Interventions. Papers, record 39200096. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/39200096

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Diabetes and Osteoarthritis: Exploring the Interactions and Therapeutic Implications of Insulin, Metformin, and GLP-1-Based Interventions.
PubMed
Journal
Biomedicines
PubMed
Year
2024
PubMed
Publication types
Journal Article, Review
PubMed
Citations, by iCite
43
iCite
Relative citation ratio, by iCite
8.98, provisional
iCite
Revised in PubMed
2024-09-01
PubMed

Authors4

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Halabitska IIrynahttps://orcid.org/0000-0002-9028-7230
2Babinets LLiliia
3Oksenych VValentynhttps://orcid.org/0000-0002-5088-3791
4Kamyshnyi OOleksandrhttps://orcid.org/0000-0003-3141-4436

Source PubMed

Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants0

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

None in this release.

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References232

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
122,343,371Role of autophagy in aging.J Cardiovasc Pharmacol2012https://conductscience.org/library/papers/22343371PubMed
238,232,692Very-low-density lipoprotein triglyceride and free fatty acid plasma kinetics in women with high or low brown adipose tissue volume and overweight/obesity.Cell Rep Med2024https://conductscience.org/library/papers/38232692PubMed
318,983,503Insulin inhibits tissue factor expression in monocytes.J Thromb Haemost2009https://conductscience.org/library/papers/18983503PubMed
436,230,974Metformin Prevents or Delays the Development and Progression of Osteoarthritis: New Insight and Mechanism of Action.Cells2022https://conductscience.org/library/papers/36230974PubMed
533,771,189Impact of disease activity on impaired glucose metabolism in patients with rheumatoid arthritis.Arthritis Res Ther2021https://conductscience.org/library/papers/33771189PubMed
629,399,540Drug Interactions of Metformin Involving Drug Transporter Proteins.Adv Pharm Bull2017https://conductscience.org/library/papers/29399540PubMed
719,725,147Problems associated with glucose toxicity: role of hyperglycemia-induced oxidative stress.World J Gastroenterol2009https://conductscience.org/library/papers/19725147PubMed
831,655,472Osteoporosis and osteoarthritis are two sides of the same coin paid for obesity.Nutrition2020https://conductscience.org/library/papers/31655472PubMed
927,114,387Type 2 diabetes and osteoarthritis: a systematic review and meta-analysis.J Diabetes Complications2016https://conductscience.org/library/papers/27114387PubMed
1029,510,522The Balance of Th17 versus Treg Cells in Autoimmunity.Int J Mol Sci2018https://conductscience.org/library/papers/29510522PubMed

1 to 10 of 232

See all 232 references

Cited by36

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 43 citations.

PMIDTitleJournalYearIn PapersSource
42,729,817Exploring the therapeutic applications of metformin in articular cartilage repair: mechanistic insights and translational perspectives.Front Immunol2026https://conductscience.org/library/papers/42729817PubMed
42,662,965Metabolic disorders and osteoarthritis: novel insights into pathological mechanisms and therapeutic strategies.Life Med2026https://conductscience.org/library/papers/42662965PubMed
42,464,553[Research progress on immune microenvironment imbalance and targeted interventions in osteoarthritis comorbid with diabetes mellitus].Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi2026https://conductscience.org/library/papers/42464553PubMed
42,453,583Integrating network toxicology and in vitro validation to elucidate PET microplastic-induced osteoarthritis pathogenesis.Front Pharmacol2026https://conductscience.org/library/papers/42453583PubMed
42,429,052Endocrine‑metabolic imbalance drives osteoarthritis: From whole‑joint pathobiology to precision therapy (Review).Int J Mol Med2026https://conductscience.org/library/papers/42429052PubMed
42,371,366Association of metformin with osteoarthritis progression and total joint arthroplasty: evidence from the UK Biobank, a large population-based cohort study.Clin Rheumatol2026https://conductscience.org/library/papers/42371366PubMed
42,276,983Novel therapeutic strategies for osteoarthritis: from mechanistic insights to precision medicine.Bone Res2026https://conductscience.org/library/papers/42276983PubMed
42,239,648Diabetes-Related Metabolic Osteoarthritis: Advanced Glycation-Collagen Axis, Cartilage Stiffening, and Biomaterials-Based Therapeutic Strategies.Int J Nanomedicine2026https://conductscience.org/library/papers/42239648PubMed
42,183,581Tackling obesity's impact: the need to address metabolic syndrome in osteoarthritis management.Future Sci OA2026https://conductscience.org/library/papers/42183581PubMed
42,101,662The effect of GLP-1 receptor agonists on osteoarthritis risk in individuals with type 2 diabetes mellitus: a systematic review and network meta-analysis of randomized controlled trials.Acta Diabetol2026https://conductscience.org/library/papers/42101662PubMed

1 to 10 of 36

See all 36 cited by

Genes3

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
GLP1R2,740PubTator's text mininghttps://conductscience.org/library/genes/2740NCBI Gene
INS3,630PubTator's text mininghttps://conductscience.org/library/genes/3630NCBI Gene
PRKAA15,562PubTator's text mininghttps://conductscience.org/library/genes/5562NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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