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Paper · 39716914

Glycerol-3-phosphate contributes to the increase in FGF23 production in chronic kidney disease.

Simic P and 7 others. Am J Physiol Renal Physiol, 2025. Cited by 12 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Glycerol-3-phosphate contributes to the increase in FGF23 production in chronic kidney disease. Papers, record 39716914. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/39716914

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Glycerol-3-phosphate contributes to the increase in FGF23 production in chronic kidney disease.
PubMed
Journal
Am J Physiol Renal Physiol
PubMed
Year
2025
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural
PubMed
Citations, by iCite
12
iCite
Relative citation ratio, by iCite
3.65, provisional
iCite
Revised in PubMed
2026-06-08
PubMed

Authors8

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Simic PPetra
2Xie HHan
3Zhang QQian
4Zhou WWen
5Cherukuru RRohanhttps://orcid.org/0009-0002-2866-0855
6Adams MAMichael A
7Turner MEMandy E
8Rhee EPEugene Phttps://orcid.org/0000-0002-4804-7583

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Renal Insufficiency, ChronicMajor topic
Fibroblast Growth FactorsMajor topic
GlycerophosphatesMajor topic
KidneyMajor topic
Animals
Fibroblast Growth Factor-23
Male
Mice, Knockout
Glycerolphosphate Dehydrogenase
Rats
Adenine
Disease Models, Animal
Mice
Mice, Inbred C57BL
Rats, Sprague-Dawley
Phosphates

Source PubMed

Grants5

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
P30 AR075042NIAMS NIH HHSUnited StatesP30AR075042PubMed and NIHNIH RePORTER
R01 DK130291NIDDK NIH HHSUnited StatesR01DK130291PubMed and NIHNIH RePORTER
K08DK124568HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)K08DK124568PubMed and NIHNIH RePORTER
K08 DK124568NIDDK NIH HHSUnited StatesK08DK124568PubMed and NIHNIH RePORTER
R01DK130291HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)R01DK130291PubMed and NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References25

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
138,661,434Fibroblast growth factor 23 is pumping iron: C-terminal-fibroblast growth factor 23 cleaved peptide and its function in iron metabolism.Curr Opin Nephrol Hypertens2024https://conductscience.org/library/papers/38661434PubMed
231,668,375Longitudinal Evolution of Markers of Mineral Metabolism in Patients With CKD: The Chronic Renal Insufficiency Cohort (CRIC) Study.Am J Kidney Dis2020https://conductscience.org/library/papers/31668375PubMed
324,385,590Renal cortical pyruvate depletion during AKI.J Am Soc Nephrol2014https://conductscience.org/library/papers/24385590PubMed
434,185,705Calcium phosphate microcrystals in the renal tubular fluid accelerate chronic kidney disease progression.J Clin Invest2021https://conductscience.org/library/papers/34185705PubMed
515,917,335Fibroblast growth factor-23 mitigates hyperphosphatemia but accentuates calcitriol deficiency in chronic kidney disease.J Am Soc Nephrol2005https://conductscience.org/library/papers/15917335PubMed
631,602,417New concepts in feedback regulation of glucose metabolism.Curr Opin Syst Biol2018https://conductscience.org/library/papers/31602417PubMed
736,190,819Vascular calcification maladaptively participates in acute phosphate homeostasis.Cardiovasc Res2023https://conductscience.org/library/papers/36190819PubMed
829,482,575i-GONAD: a robust method for in situ germline genome engineering using CRISPR nucleases.Genome Biol2018https://conductscience.org/library/papers/29482575PubMed
932,065,590Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney.J Clin Invest2020https://conductscience.org/library/papers/32065590PubMed
1032,001,068Calciprotein particles regulate fibroblast growth factor-23 expression in osteoblasts.Kidney Int2020https://conductscience.org/library/papers/32001068PubMed

Cited by6

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 12 citations.

PMIDTitleJournalYearIn PapersSource
42,663,891FGF23 - A hormone produced by bone and has many faces.Rev Endocr Metab Disord2026https://conductscience.org/library/papers/42663891PubMed
42,020,815Broken signals: when the mineralostat alters the cardiovascular system.Pediatr Nephrol2026https://conductscience.org/library/papers/42020815PubMed
41,767,622Markers of Mineral Metabolism in Children With CKD Stages 2 to 5D.Kidney Int Rep2026https://conductscience.org/library/papers/41767622PubMed
41,699,300A genetically encoded bifunctional enzyme mitigates redox imbalance and lipotoxicity.Nat Metab2026https://conductscience.org/library/papers/41699300PubMed
41,683,565High-Phosphate-Induced Hypertension: The Pathogenic Role of Fibroblast Growth Factor 23 (FGF23) Signaling in Sympathetic Nervous System Activation.Int J Mol Sci2026https://conductscience.org/library/papers/41683565PubMed
41,105,473Association between Serum Glycerol-3-Phosphate and Fibroblast Growth Factor-23 in Nondiabetic Patients on Hemodialysis.Clin J Am Soc Nephrol2026https://conductscience.org/library/papers/41105473PubMed

Genes3

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
FGF238,074PubTator's text mininghttps://conductscience.org/library/genes/8074NCBI Gene
GPD12,819PubTator's text mininghttps://conductscience.org/library/genes/2819NCBI Gene
PTH5,741PubTator's text mininghttps://conductscience.org/library/genes/5741NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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