Paper · 41301931
TIM-3 Promotes Proliferation of Acute Myeloid Leukemia Blasts.
Shi ZY and 4 others. Biomedicines, 2025. Cited by 2 papers, by iCite.
11 sourcespapers-2026-11-12-0.1.0
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ConductScience Library. TIM-3 Promotes Proliferation of Acute Myeloid Leukemia Blasts. Papers, record 41301931. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41301931
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Paper
PubMed's record of the paper, with iCite's citation figures. No abstract is shown.
Topics0
NLM's MeSH indexing of the paper, its major topics first.
None in this release.
Grants1
Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.
| Grant, as the record writes it | Agency | Country | NIH project | Stated by |
|---|---|---|---|---|
| 82070153 | National Natural Science Foundation of China | PubMed |
Source PubMed
Trials0
The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.
None in this release.
Comments and corrections0
PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.
None in this release.
References31
The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.
| Order | PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|---|
| 1 | 29,449,693 | Tumor cell-intrinsic Tim-3 promotes liver cancer via NF-κB/IL-6/STAT3 axis. | Oncogene | 2018 | https://conductscience.org/library/papers/29449693 | PubMed |
| 2 | 32,184,631 | TIM-3 Participates in the Invasion and Metastasis of Nasopharyngeal Carcinoma via SMAD7/SMAD2/SNAIL1 Axis-Mediated Epithelial-Mesenchymal Transition. | Onco Targets Ther | 2020 | https://conductscience.org/library/papers/32184631 | PubMed |
| 3 | 24,195,506 | Prognostic implication of TIM-3 in clear cell renal cell carcinoma. | Neoplasma | 2014 | https://conductscience.org/library/papers/24195506 | PubMed |
| 4 | 16,286,920 | The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity. | Nat Immunol | 2005 | https://conductscience.org/library/papers/16286920 | PubMed |
| 5 | 33,692,857 | Expression of immune check point gene TIM-3 in patients newly diagnosed with acute myeloid leukemia: Significance and impact on outcome. | Oncol Lett | 2021 | https://conductscience.org/library/papers/33692857 | PubMed |
| 6 | 29,254,227 | High Tim-3 expression on AML blasts could enhance chemotherapy sensitivity. | Oncotarget | 2017 | https://conductscience.org/library/papers/29254227 | PubMed |
| 7 | 31,612,039 | TIM-3 expression and its association with overall survival in primary osteosarcoma. | Oncol Lett | 2019 | https://conductscience.org/library/papers/31612039 | PubMed |
| 8 | 11,357,141 | Proliferation, cell cycle and apoptosis in cancer. | Nature | 2001 | https://conductscience.org/library/papers/11357141 | PubMed |
| 9 | 1,312,467 | Cyclin A is required at two points in the human cell cycle. | EMBO J | 1992 | https://conductscience.org/library/papers/1312467 | PubMed |
| 10 | 28,035,413 | Tim-3 is upregulated in human colorectal carcinoma and associated with tumor progression. | Mol Med Rep | 2017 | https://conductscience.org/library/papers/28035413 | PubMed |
1 to 10 of 31
See all 31 referencesCited by2
The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 2 citations.
| PMID | Title | Journal | Year | In Papers | Source |
|---|---|---|---|---|---|
| 42,214,672 | Dysregulated HELLS expression alters cellular processes and serves as a potential prognostic marker in acute myeloid leukemia. | J Biol Chem | 2026 | https://conductscience.org/library/papers/42214672 | PubMed |
| 42,157,277 | TIM-3 in AML: a janus-faced orchestrator of immune exhaustion and leukemic self-renewal. | Cancer Cell Int | 2026 | https://conductscience.org/library/papers/42157277 | PubMed |
Genes11
The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.
| Gene | NCBI Gene ID | Linked by | In Genes | Source |
|---|---|---|---|---|
| AURKB | 9,212 | PubTator's text mining | https://conductscience.org/library/genes/9212 | NCBI Gene |
| CCNA2 | 890 | PubTator's text mining | https://conductscience.org/library/genes/890 | NCBI Gene |
| CD34 | 947 | PubTator's text mining | https://conductscience.org/library/genes/947 | NCBI Gene |
| CDCA5 | 113,130 | PubTator's text mining | https://conductscience.org/library/genes/113130 | NCBI Gene |
| CDK1 | 983 | PubTator's text mining | https://conductscience.org/library/genes/983 | NCBI Gene |
| CEBPZ | 10,153 | PubTator's text mining | https://conductscience.org/library/genes/10153 | NCBI Gene |
| HAVCR2 | 84,868 | PubTator's text mining | https://conductscience.org/library/genes/84868 | NCBI Gene |
| NDC80 | 10,403 | PubTator's text mining | https://conductscience.org/library/genes/10403 | NCBI Gene |
| SGO1 | 151,648 | PubTator's text mining | https://conductscience.org/library/genes/151648 | NCBI Gene |
| TICRR | 90,381 | PubTator's text mining | https://conductscience.org/library/genes/90381 | NCBI Gene |
1 to 10 of 11
See all 11 genesDrugs0
The drugs whose trials, in the Pipelines release, list the paper.
None in this release.
Data0
The data bank entries PubMed's record names. Trial numbers are under Trials.
None in this release.
Data dates
The date of each source this release read.
- Trials
- 2026-11-12
- Gene search
- 2026-11-11
- Pipelines
- 2026-09-18
Sources 11
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- HGNCCC0
- iCiteCC BY 4.0
- NCBI GenePublic domain (US government)
- NIH RePORTER's grant and paper linksPublic domain
- Open TargetsCC0 1.0
- PMC's ID filePublic domain (US government)
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- HGNCCC0: https://www.genenames.org/about/license/
- iCiteCC BY 4.0
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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