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Paper · 41596293

Osteoporosis After Menopause and After Drug Therapy: The Molecular Mechanism of Bone Loss and Its Treatment.

Lee KI and 2 others. Int J Mol Sci, 2026. Cited by 16 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Osteoporosis After Menopause and After Drug Therapy: The Molecular Mechanism of Bone Loss and Its Treatment. Papers, record 41596293. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/41596293

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Osteoporosis After Menopause and After Drug Therapy: The Molecular Mechanism of Bone Loss and Its Treatment.
PubMed
Journal
Int J Mol Sci
PubMed
Year
2026
PubMed
Publication types
Journal Article, Review
PubMed
Citations, by iCite
16
iCite
Relative citation ratio, by iCite
11.14, provisional
iCite
Revised in PubMed
2026-07-01
PubMed

Authors3

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Lee KIKelly I-Rong
2Chen JHJie-Hong
3Chen KHKuo-Huhttps://orcid.org/0000-0002-4758-0351

Source PubMed

Topics10

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Bone Density Conservation AgentsMajor topic
Osteoporosis, PostmenopausalMajor topic
OsteoporosisMajor topic
Humans
Female
Denosumab
Animals
Bone Remodeling
Diphosphonates
RANK Ligand

Source PubMed

Grants1

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated by
TCRD-TPE-114-12Taipei Tzu Chi HospitalPubMed

Source PubMed

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References169

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
135,478,046The clinician's guide to prevention and treatment of osteoporosis.Osteoporos Int2022https://conductscience.org/library/papers/35478046PubMed
221,450,337Osteoporosis: now and the future.Lancet2011https://conductscience.org/library/papers/21450337PubMed
329,955,628Bisphosphonate-related osteonecrosis of the jaw: a mechanobiology perspective.Bone Rep2018https://conductscience.org/library/papers/29955628PubMed
416,936,272B and T lymphocytes are the primary sources of RANKL in the bone resorptive lesion of periodontal disease.Am J Pathol2006https://conductscience.org/library/papers/16936272PubMed
519,209,265The use of calcium and vitamin D in the management of osteoporosis.Ther Clin Risk Manag2008https://conductscience.org/library/papers/19209265PubMed
638,655,459Identification of an novel genetic variant associated with osteoporosis: insights from the Taiwan Biobank Study.JBMR Plus2024https://conductscience.org/library/papers/38655459PubMed
732,757,960Associations between polymorphisms in VDR gene and the risk of osteoporosis: a meta-analysis.Arch Physiol Biochem2022https://conductscience.org/library/papers/32757960PubMed
822,595,550Estrogen and the skeleton.Trends Endocrinol Metab2012https://conductscience.org/library/papers/22595550PubMed
927,053,737Physiological Bone Remodeling: Systemic Regulation and Growth Factor Involvement.Physiology (Bethesda)2016https://conductscience.org/library/papers/27053737PubMed
1035,933,897
Shilajit extract reduces oxidative stress, inflammation, and bone loss to dose-dependently preserve bone mineral density in postmenopausal women with osteopenia: A randomized, double-blind, placebo-controlled trial.
Phytomedicine2022https://conductscience.org/library/papers/35933897PubMed

Cited by17

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 16 citations.

PMIDTitleJournalYearIn PapersSource
42,942,894Whey Protein-Polysaccharide Nanocomplexes: Structure-Function Characterization and Bone-Related Outcomes in Ovariectomized Rats.Nutrients2026https://conductscience.org/library/papers/42942894PubMed
42,793,202Nuciferine Ameliorates Ovariectomy-Induced Bone Loss via TFEB-Mediated Autophagy-Lysosomal Pathway.Biomolecules2026https://conductscience.org/library/papers/42793202PubMed
42,761,519Targeting subchondral osteoporosis in osteoarthritis: biomechanical crosstalk and the therapeutic rationale for inflammatory microenvironment remodeling.Front Immunol2026https://conductscience.org/library/papers/42761519PubMed
42,739,052Bioactive Phytochemicals from Artocarpus integer Leaves Improve Bone-Related Outcomes in Ovariectomized Rats: An Integrated LC-HRMS, Network Pharmacology, and Experimental Study.Nutrients2026https://conductscience.org/library/papers/42739052PubMed
42,713,413Comparison of Naringenin and Alendronate in the Attenuation of Ovariectomy-Induced Osteoporosis by Modulating Autophagy, Apoptosis, and Oxidative Stress in Rats.Iran J Pharm Res2026https://conductscience.org/library/papers/42713413PubMed
42,706,713Prevalence and Associated Risk Factors of Osteoporosis in Community-Dwelling Older Adults in China: A Cross-Sectional Study of 2533 Participants.Med Sci Monit2026https://conductscience.org/library/papers/42706713PubMed
42,639,398The multisystem impact of perimenopausal hormonal fluctuations on chronic disease risk.Front Endocrinol (Lausanne)2026https://conductscience.org/library/papers/42639398PubMed
42,597,306Circadian regulation of osteoclast lysosomal-resorption machinery: implications for osteoporosis therapy.Front Cell Dev Biol2026https://conductscience.org/library/papers/42597306PubMed
42,382,177The recent progression of extracellular vesicles application in osteoporosis.Front Pharmacol2026https://conductscience.org/library/papers/42382177PubMed
42,351,672Humic Acid Therapy Mitigates Estrogen Deficiency-Induced Alveolar Bone Loss and Modulates the RANKL/OPG Balance.Biomedicines2026https://conductscience.org/library/papers/42351672PubMed

1 to 10 of 17

See all 17 cited by

Genes3

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
CTNNB11,499PubTator's text mininghttps://conductscience.org/library/genes/1499NCBI Gene
SOST50,964PubTator's text mininghttps://conductscience.org/library/genes/50964NCBI Gene
TNFSF118,600PubTator's text mininghttps://conductscience.org/library/genes/8600NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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