Paper · 42417469

Impact of vitamin D on the colon cancer immune microenvironment: results of a randomized clinical trial of preoperative vitamin D supplementation in patients with stage I-III colon cancer.

Dias Costa A and 28 others. Cancer Discov, 2026. Cited by 2 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Impact of vitamin D on the colon cancer immune microenvironment: results of a randomized clinical trial of preoperative vitamin D supplementation in patients with stage I-III colon cancer. Papers, record 42417469. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42417469

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title: Impact of vitamin D on the colon cancer immune microenvironment: results of a randomized clinical trial of preoperative vitamin D supplementation in patients with stage I-III colon cancer.; PubMed
Journal: Cancer Discov; PubMed
Year: 2026; PubMed
Publication types: Journal Article; PubMed
PubMed: https://pubmed.ncbi.nlm.nih.gov/42417469/; PubMed
DOI: https://doi.org/10.1158/2159-8290.cd-25-1574; PubMed
PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC13403174/; PubMed
The journal: https://conductscience.org/library/journal-index/101561693; PubMed
Citations, by iCite: 2; iCite
Revised in PubMed: 2026-08-23; PubMed

Authors29

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

Order	Author	Forename	ORCID iD
1	Dias Costa A	Andressa	https://orcid.org/0000-0003-1046-4899
2	Kim S	Suryun	https://orcid.org/0000-0002-6079-379X
3	Hong SC	Sung Chul	https://orcid.org/0009-0007-4394-5820
4	Yuan C	Chen	https://orcid.org/0000-0002-0708-9648
5	Qi X	Xinran	https://orcid.org/0000-0002-1348-5444
6	Zhang J	Jinming	https://orcid.org/0000-0003-1621-7549
7	Bleday R	Ronald	https://orcid.org/0000-0001-9861-7911
8	Goldberg J	Joel	https://orcid.org/0000-0002-2209-1631
9	Irani J	Jennifer	https://orcid.org/0000-0003-0174-7571
10	Melnitchouk N	Nelya	https://orcid.org/0000-0002-7223-9526

1 to 10 of 29Source PubMed

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Topics0

NLM's MeSH indexing of the paper, its major topics first.

None in this release.

Grants2

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes it	Agency	Country	NIH project	Stated by	Source
P50 CA127003	NCI NIH HHS	United States	P50CA127003	PubMed	NIH RePORTER
R01 CA205406	NCI NIH HHS	United States	R01CA205406	PubMed	NIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References63

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

Order	PMID	Title	Journal	Year	In Papers	Source
1	36,670,267	Therapeutic landscape and future direction of metastatic colorectal cancer.	Nat Rev Gastroenterol Hepatol	2023	https://conductscience.org/library/papers/36670267	PubMed
2	27,246,684	Plasma 25-Hydroxyvitamin D, Vitamin D Binding Protein, and Risk of Colorectal Cancer in the Nurses' Health Study.	Cancer Prev Res (Phila)	2016	https://conductscience.org/library/papers/27246684	PubMed
3	21,245,434	TNM staging in colorectal cancer: T is for T cell and M is for memory.	J Clin Oncol	2011	https://conductscience.org/library/papers/21245434	PubMed
4	22,503,810	Where is the vitamin D receptor?	Arch Biochem Biophys	2012	https://conductscience.org/library/papers/22503810	PubMed
5	28,327,908	Predicted vitamin D status and colon cancer recurrence and mortality in CALGB 89803 (Alliance).	Ann Oncol	2017	https://conductscience.org/library/papers/28327908	PubMed
6	30,011,816	Association between Blood 25-Hydroxyvitamin D Levels and Survival in Colorectal Cancer Patients: An Updated Systematic Review and Meta-Analysis.	Nutrients	2018	https://conductscience.org/library/papers/30011816	PubMed
7	20,208,539	Vitamin D controls T cell antigen receptor signaling and activation of human T cells.	Nat Immunol	2010	https://conductscience.org/library/papers/20208539	PubMed
8	28,947,884	Expression of vitamin D receptor and vitamin D status in patients with oral neoplasms and effect of vitamin D supplementation on quality of life in advanced cancer treatment.	Contemp Oncol (Pozn)	2017	https://conductscience.org/library/papers/28947884	PubMed
9	32,763,154	Coordinated Cellular Neighborhoods Orchestrate Antitumoral Immunity at the Colorectal Cancer Invasive Front.	Cell	2020	https://conductscience.org/library/papers/32763154	PubMed
10	19,946,335	Immune infiltration in human tumors: a prognostic factor that should not be ignored.	Oncogene	2010	https://conductscience.org/library/papers/19946335	PubMed

1 to 10 of 63

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Cited by3

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 2 citations.

PMID	Title	Journal	Year	In Papers	Source
41,831,062	Photodynamic priming with Vitamin D and ALA-based PDT induces intratumoral immune cell recruitment and signaling pathway activation in cutaneous squamous cell carcinoma.	Cancer Immunol Immunother	2026	https://conductscience.org/library/papers/41831062	PubMed
41,676,633	Photodynamic priming with Vitamin D and ALA-based PDT induces intratumoral immune cell recruitment and signaling pathway activation in murine cutaneous squamous cell carcinoma.	bioRxiv	2026	https://conductscience.org/library/papers/41676633	PubMed
38,927,564	Vitamin D3 (Calcitriol) Monotherapy Decreases Tumor Growth, Increases Survival, and Correlates with Low Neutrophil-to-Lymphocyte Ratio in a Murine HPV-16-Related Cancer Model.	Biomedicines	2024	https://conductscience.org/library/papers/38927564	PubMed

Genes5

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

Gene	NCBI Gene ID	Linked by	In Genes	Source
CD4	920	PubTator's text mining	https://conductscience.org/library/genes/920	NCBI Gene
CD8A	925	PubTator's text mining	https://conductscience.org/library/genes/925	NCBI Gene
CYP27B1	1,594	PubTator's text mining	https://conductscience.org/library/genes/1594	NCBI Gene
FOXP3	50,943	PubTator's text mining	https://conductscience.org/library/genes/50943	NCBI Gene
VDR	7,421	PubTator's text mining	https://conductscience.org/library/genes/7421	NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed: 2026-11-06; PubMed
iCite: 2026-11-05; iCite
PMC's ID file: 2026-11-05; PMC's ID file
NIH RePORTER's grant and paper links: 2026-11-01; NIH RePORTER's grant and paper links
Trials: 2026-11-12
Gene search: 2026-11-11
Pipelines: 2026-09-18

Sources 11

ChEMBL, through Open TargetsCC BY-SA 3.0
ClinicalTrials.govNo license stated
HGNCCC0
iCiteCC BY 4.0
NCBI GenePublic domain (US government)
NIH RePORTER's grant and paper linksPublic domain
Open TargetsCC0 1.0
PMC's ID filePublic domain (US government)
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0

Each source's terms

ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
ClinicalTrials.govnone stated
HGNCCC0: https://www.genenames.org/about/license/
iCiteCC BY 4.0
NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
PubMedNLM's terms
PubTator 3Public domain
UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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