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Paper · 42809705

Auranofin Potentiates Cisplatin Response in the Setting of Context-Dependent NOTCH-Associated Signaling States in Endometrial Cancer.

Lake RJ and 8 others. Cancer Res Commun, 2026.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Auranofin Potentiates Cisplatin Response in the Setting of Context-Dependent NOTCH-Associated Signaling States in Endometrial Cancer. Papers, record 42809705. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/42809705

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Auranofin Potentiates Cisplatin Response in the Setting of Context-Dependent NOTCH-Associated Signaling States in Endometrial Cancer.
Journal
Cancer Res Commun
Year
2026
Publication types
Journal Article
Revised in PubMed
2026-11-06

Source PubMed

Authors9

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Lake RJRobert Jhttps://orcid.org/0009-0001-7196-5710
2Tshibangu CCynthiahttps://orcid.org/0009-0003-2063-5177
3Candia NJNiko Jhttps://orcid.org/0009-0009-9102-7439
4Abfalterer QUQuinn Uhttps://orcid.org/0000-0001-8456-5663
5Lagutina IVIrina Vhttps://orcid.org/0000-0001-9538-4008
6Pauken CChristinehttps://orcid.org/0009-0007-0748-1272
7Leslie KKKimberly Khttps://orcid.org/0000-0002-2704-8990
8Steinkamp MPMara Phttps://orcid.org/0000-0003-1226-9325
9Fan HYHua-Yinghttps://orcid.org/0000-0003-1790-4041

Source PubMed

Topics16

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Endometrial NeoplasmsMajor topic
AuranofinMajor topic
CisplatinMajor topic
Receptors, NotchMajor topic
Receptor, Notch3Major topic
Antineoplastic Combined Chemotherapy ProtocolsMajor topic
Female
Humans
Animals
Signal Transduction
Mice
Cell Line, Tumor
Drug Synergism
Xenograft Model Antitumor Assays
Drug Resistance, Neoplasm
Gene Expression Regulation, Neoplastic

Source PubMed

Grants7

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
21CA286210National Cancer Institute (NCI)PubMedPubMed
P30CA118100Center for Cancer Research (CCR)P30CA118100PubMedNIH RePORTER
R21 CA286210NCI NIH HHSUnited StatesR21CA286210PubMedNIH RePORTER
CA210610U.S. Department of War (DOW)PubMedPubMed
OC230061U.S. Department of War (DOW)PubMedPubMed
P50CA265793National Cancer Institute (NCI)P50CA265793PubMedNIH RePORTER
P30 CA118100NCI NIH HHSUnited StatesP30CA118100PubMedNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References44

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
140,985,842Auranofin Synergizes with Cisplatin in Reducing Tumor Burden of NOTCH-Dependent Ovarian Cancer.Cancer Res Commun2025https://conductscience.org/library/papers/40985842PubMed
238,269,508Auranofin sensitizes breast cancer cells to paclitaxel mediated cell death via regulating FOXO3/Nrf2/Keap1 signaling pathway.Cell Biochem Funct2024https://conductscience.org/library/papers/38269508PubMed
337,712,875A Phase I Study of the Pan-Notch Inhibitor CB-103 for Patients with Advanced Adenoid Cystic Carcinoma and Other Tumors.Cancer Res Commun2023https://conductscience.org/library/papers/37712875PubMed
424,298,019Notch-Nrf2 axis: regulation of Nrf2 gene expression and cytoprotection by notch signaling.Mol Cell Biol2014https://conductscience.org/library/papers/24298019PubMed
517,525,745Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes.Oncogene2007https://conductscience.org/library/papers/17525745PubMed
637,165,578FGFR2 mutations promote endometrial cancer progression through dual engagement of EGFR and Notch signalling pathways.Clin Transl Med2023https://conductscience.org/library/papers/37165578PubMed
733,284,507Gamma Secretase Inhibitors in Cancer: A Current Perspective on Clinical Performance.Oncologist2021https://conductscience.org/library/papers/33284507PubMed
841,154,495The Redox Paradox: Cancer's Double-Edged Sword for Malignancy and Therapy.Antioxidants (Basel)2025https://conductscience.org/library/papers/41154495PubMed
940,052,152Notch signaling in cancers: mechanism and potential therapy.Front Cell Dev Biol2025https://conductscience.org/library/papers/40052152PubMed
1023,019,585Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy.Proc Natl Acad Sci U S A2012https://conductscience.org/library/papers/23019585PubMed

1 to 10 of 44

See all 44 references

Cited by0

The papers in our copy of PubMed whose reference list names this one, newest first.

None in this release.

Genes5

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
HES13,280PubTator's text mininghttps://conductscience.org/library/genes/3280NCBI Gene
HES457,801PubTator's text mininghttps://conductscience.org/library/genes/57801NCBI Gene
NOTCH34,854PubTator's text mininghttps://conductscience.org/library/genes/4854NCBI Gene
PRDX525,824PubTator's text mininghttps://conductscience.org/library/genes/25824NCBI Gene
RBPJ3,516PubTator's text mininghttps://conductscience.org/library/genes/3516NCBI Gene

Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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