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Paper · 17525745

Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes.

Pollock PM and 10 others. Oncogene, 2007. Cited by 248 papers, by iCite.

11 sourcespapers-2026-11-12-0.1.0

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ConductScience Library. Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes. Papers, record 17525745. Release papers-2026-11-12-0.1.0, 12 Nov 2026. https://conductscience.org/library/papers/17525745

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Paper

PubMed's record of the paper, with iCite's citation figures. No abstract is shown.

Title
Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes.
PubMed
Journal
Oncogene
PubMed
Year
2007
PubMed
Publication types
Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't
PubMed
Citations, by iCite
248
iCite
Relative citation ratio, by iCite
4.89
iCite
Revised in PubMed
2026-11-02
PubMed

Authors11

The authors in the order PubMed's record lists them, with the ORCID iDs it states.

OrderAuthorForenameKindORCID iD
1Pollock PMP M
2Gartside MGM G
3Dejeza LCL C
4Powell MAM A
5Mallon MAM A
6Davies HH
7Mohammadi MM
8Futreal PAP A
9Stratton MRM R
10Trent JMJ M

1 to 10 of 11Source PubMed

See all 11 authors

Topics12

NLM's MeSH indexing of the paper, its major topics first.

MeSH termMajor
Bone Diseases, DevelopmentalMajor topic
Carcinoma, EndometrioidMajor topic
CarcinosarcomaMajor topic
CraniosynostosesMajor topic
Endometrial NeoplasmsMajor topic
Germ-Line MutationMajor topic
Receptor, Fibroblast Growth Factor, Type 2Major topic
Aged
Amino Acid Substitution
Cell Line, Tumor
Female
Humans

Source PubMed

Grants4

Each grant PubMed's record writes, matched to the NIH project NIH's grant and paper links name for this paper, and each of those links the record does not write.

Grant, as the record writes itAgencyCountryNIH projectStated bySource
077012Wellcome TrustUnited KingdomPubMedPubMed
R01 CA71754NCI NIH HHSUnited StatesR01CA071754PubMed and NIHNIH RePORTER
CA091842NCI NIH HHSUnited StatesP30CA091842PubMed and NIHNIH RePORTER
R01CA109544NIHNIH RePORTER

Trials0

The trials whose ClinicalTrials.gov record lists the paper, and the trial numbers the paper's PubMed record names.

None in this release.

Comments and corrections0

PubMed's comments and corrections, NLM's own indexing: retractions first, then expressions of concern, errata and updates, and comments last.

None in this release.

References22

The papers the reference list in PubMed's record names, those in our copy of PubMed, in the list's order.

OrderPMIDTitleJournalYearIn PapersSource
111,245,416The fibroblast growth factor receptor 3 (FGFR3) mutation is a strong indicator of superficial bladder cancer with low recurrence rate.Cancer Res2001https://conductscience.org/library/papers/11245416PubMed
211,121,055Loss of fibroblast growth factor receptor 2 ligand-binding specificity in Apert syndrome.Proc Natl Acad Sci U S A2000https://conductscience.org/library/papers/11121055PubMed
311,058,137Analysis of canonical and non-canonical splice sites in mammalian genomes.Nucleic Acids Res2000https://conductscience.org/library/papers/11058137PubMed
410,611,230The transmembrane mutation G380R in fibroblast growth factor receptor 3 uncouples ligand-mediated receptor activation from down-regulation.Mol Cell Biol2000https://conductscience.org/library/papers/10611230PubMed
517,344,846Patterns of somatic mutation in human cancer genomes.Nature2007https://conductscience.org/library/papers/17344846PubMed
616,981,669Chemotherapy in endometrial cancer.Clin Adv Hematol Oncol2006https://conductscience.org/library/papers/16981669PubMed
716,597,617Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.J Biol Chem2006https://conductscience.org/library/papers/16597617PubMed
816,514,137Cancer statistics, 2006.CA Cancer J Clin2006https://conductscience.org/library/papers/16514137PubMed
915,863,034Bad bones, absent smell, selfish testes: the pleiotropic consequences of human FGF receptor mutations.Cytokine Growth Factor Rev2005https://conductscience.org/library/papers/15863034PubMed
1015,863,029Structural basis for fibroblast growth factor receptor activation.Cytokine Growth Factor Rev2005https://conductscience.org/library/papers/15863029PubMed

1 to 10 of 22

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Cited by138

The papers in our copy of PubMed whose reference list names this one, newest first. iCite, which reads more sources, counts 248 citations.

PMIDTitleJournalYearIn PapersSource
42,809,705Auranofin Potentiates Cisplatin Response in the Setting of Context-Dependent NOTCH-Associated Signaling States in Endometrial Cancer.Cancer Res Commun2026https://conductscience.org/library/papers/42809705PubMed
42,793,688Molecular Classification of Endometrial Cancer in the Era of Precision Oncology: Prognostic Significance, Emerging Biomarkers, and Personalized Therapeutic Strategies-A Systematic Review.Diagnostics (Basel)2026https://conductscience.org/library/papers/42793688PubMed
42,082,645Long-term survival without high cancer risk in a cohort of 24 patients with Apert syndrome.Eur J Hum Genet2026https://conductscience.org/library/papers/42082645PubMed
41,491,970Application of nanoparticles in the therapeutic management of endometrial cancer.Eur J Med Res2026https://conductscience.org/library/papers/41491970PubMed
41,226,813FGFR2 Might Be a Promising Therapeutic Target for Some Solid Tumors: Analysis of 1312 Cancers with FGFR2 Abnormalities.Int J Mol Sci2025https://conductscience.org/library/papers/41226813PubMed
40,843,798Pilomatricoma in Syndromic Contexts: A Literature Review and a Report of a Case in Apert Syndrome.Dermatopathology (Basel)2025https://conductscience.org/library/papers/40843798PubMed
40,338,217Efficacy of 2 different fibroblast growth factor receptor-inhibitors in a patient with extrahepatic cholangiocarcinoma harboring an FGFR2 mutation: a case report.Oncologist2025https://conductscience.org/library/papers/40338217PubMed
40,111,447Pelvic spindle cell sarcomas harboring MEIS1::NCOA2 fusion and novel gene amplifications in 10q23-26 region: a potential predictor for tumor progression.Virchows Arch2025https://conductscience.org/library/papers/40111447PubMed
38,525,398The Application of Artificial Intelligence and Drug Repositioning for the Identification of Fibroblast Growth Factor Receptor Inhibitors: A Review.Adv Biomed Res2024https://conductscience.org/library/papers/38525398PubMed
38,424,198FGFR-targeted therapeutics: clinical activity, mechanisms of resistance and new directions.Nat Rev Clin Oncol2024https://conductscience.org/library/papers/38424198PubMed

1 to 10 of 138

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Genes12

The genes the Gene search release ties to the paper: Swiss-Prot's references first, then PubTator's text mining.

GeneNCBI Gene IDLinked byIn GenesSource
FGF12,246PubTator's text mininghttps://conductscience.org/library/genes/2246NCBI Gene
FGF102,255PubTator's text mininghttps://conductscience.org/library/genes/2255NCBI Gene
FGF168,823PubTator's text mininghttps://conductscience.org/library/genes/8823NCBI Gene
FGF22,247PubTator's text mininghttps://conductscience.org/library/genes/2247NCBI Gene
FGF238,074PubTator's text mininghttps://conductscience.org/library/genes/8074NCBI Gene
FGF92,254PubTator's text mininghttps://conductscience.org/library/genes/2254NCBI Gene
FGFR12,260PubTator's text mininghttps://conductscience.org/library/genes/2260NCBI Gene
FGFR22,263PubTator's text mininghttps://conductscience.org/library/genes/2263NCBI Gene
FGFR32,261PubTator's text mininghttps://conductscience.org/library/genes/2261NCBI Gene
FGFR42,264PubTator's text mininghttps://conductscience.org/library/genes/2264NCBI Gene

1 to 10 of 12

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Drugs0

The drugs whose trials, in the Pipelines release, list the paper.

None in this release.

Data0

The data bank entries PubMed's record names. Trial numbers are under Trials.

None in this release.

Data dates

The date of each source this release read.

PubMed
2026-11-06
PubMed
iCite
2026-11-05
iCite
PMC's ID file
2026-11-05
PMC's ID file
NIH RePORTER's grant and paper links
2026-11-01
NIH RePORTER's grant and paper links
Trials
2026-11-12
Gene search
2026-11-11
Pipelines
2026-09-18

Sources 11

  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • HGNCCC0
  • iCiteCC BY 4.0
  • NCBI GenePublic domain (US government)
  • NIH RePORTER's grant and paper linksPublic domain
  • Open TargetsCC0 1.0
  • PMC's ID filePublic domain (US government)
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • HGNCCC0: https://www.genenames.org/about/license/
  • iCiteCC BY 4.0
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH RePORTER's grant and paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PMC's ID fileNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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